Dias, T. R.Bernardino, RaquelAlves, Marco GSilva, JoaquinaBarros, AlbertoSousa, MárioCasal, SusanaSilva, Branca M.Oliveira, P.F.2020-02-142020-02-142019http://hdl.handle.net/10400.6/9276L-Theanine is the major free amino acid present in tea (Camellia sinensis L.). The effects of several tea constituents on male reproduction have been investigated, but L-theanine has been overlooked. Sertoli cells (SCs) are essential for the physical and nutritional support of germ cells. In this study, we aimed to investigate the ability of L-theanine to modulate important mechanisms of human SCs (hSCs) metabolism, mitochondrial function and oxidative profile, which are essential to prevent or counteract spermatogenesis disruption in several health conditions.engCell metabolismGlutamatel-TheanineMitochondriaAntioxidantSertoli cellL-Theanine promotes cultured human Sertoli cells proliferation and modulates glucose metabolismjournal article10.1007/s00394-019-01999-2