Gomes, InêsArinto, PatríciaLopes, CarlosSantos, CeciliaBaptista, Cláudio2019-11-282019-11-282014-01http://hdl.handle.net/10400.6/7643We also would like to thank to Professor Carmen Jerónimo for her insightful comments and suggestionsSix transmembrane epithelial antigen of the prostate 1 (STEAP1) is a transmembrane protein of epithelial cells, mostly located at cell-cell junctions, and is overexpressed in several types of tumors, particularly prostate cancer. Several studies have pointed STEAP1 as a biomarker, but the clinical significance of its overexpression is not fully understood. Therefore, we aimed to establish the association of STEAP1 immunoreactivity with histologic diagnosis and clinical data of patients.engBPHBiomarkerGleason scorePINProstate cancerSTEAP1STEAP1 is overexpressed in prostate cancer and prostatic intraepithelial neoplasia lesions, and it is positively associated with Gleason scorejournal article10.1016/j.urolonc.2013.08.028