Batista, Patrícia Sofia PinhançosRodrigues, MiguelSilva, DanielaMorgado, Patrícia I.Henriques, J.Almeida, MariaSilva, Abílio P.Correia, Ilídio Joaquim Sobreira2018-03-192018-03-192013-01-01Batista, P., Rodrigues, M., Silva, D., Morgado, P.I., Henriques, J.P., Almeida, M.O., Silva, A.P. e Correia, I.J. (2013) "Characterization of the mechanical and biological properties of a new alumina scaffold", Journal of Applied Biomaterials and Functional Materials, Vol. 11(1), pp. e18-25http://hdl.handle.net/10400.6/4635Purpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: the results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. the in vivo studies revealed no systemic reaction. Conclusions: the alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.engAlumina scaffoldsBiomedical applicationsBone regenerationCeramic biomaterialsPorositySinteringjournal article10.5301/JABFM.2012.9264