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Electrospun polymeric nanofibres as wound dressings: A review

2018-09-01Journal article Restricted access
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dc.contributor.authorMiguel, Sónia P.
dc.contributor.authorFigueira, Daniela Sofia Rodrigues
dc.contributor.authorSimões, Déborah
dc.contributor.authorRibeiro, MP.
dc.contributor.authorCoutinho, Paula
dc.contributor.authorFerreira, Paula
dc.contributor.authorCorreia, Ilídio Joaquim Sobreira
dc.date.accessioned2018-08-23T08:58:44Z
dc.date.available2018-08-23T08:58:44Z
dc.date.issued2018-09-01
dc.description.abstractSkin wounds have significant morbidity and mortality rates associated. This is explained by the limited effectiveness of the currently available treatments, which in some cases do not allow the reestablishment of the structure and functions of the damaged skin, leading to wound infection and dehydration. These drawbacks may have an impact on the healing process and ultimately prompt patients’ death. For this reason, researchers are currently developing new wound dressings that enhance skin regeneration. Among them, electrospun polymeric nanofibres have been regarded as promising tools for improving skin regeneration due to their structural similarity with the extracellular matrix of normal skin, capacity to promote cell growth and proliferation and bactericidal activity as well as suitability to deliver bioactive molecules to the wound site. In this review, an overview of the recent studies concerning the production and evaluation of electrospun polymeric nanofibrous membranes for skin regenerative purposes is provided. Moreover, the current challenges and future perspectives of electrospun nanofibrous membranes suitable for this biomedical application are highlighted.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMiguel, S.P., Figueira, D.R., Simões, D., Ribeiro, M.P., Coutinho, P., Ferreira, P., Correia, I.J. (2018) "Electrospun polymeric nanofibers as wound dressings: a review", Colloids and Surfaces B: Biointerfaces, Vol. 169, pp. 60-71pt_PT
dc.identifier.doi10.1016/j.colsurfb.2018.05.011pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/5678
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationHealth Sciences Research Centre
dc.relationDevelopment of a bioactive nanofibrous membrane loaded with bioactive molecules for wound healing
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S092777651830287X?via%3Dihubpt_PT
dc.subjectDrug delivery systemspt_PT
dc.subjectPolymeric nanofibrespt_PT
dc.subjectElectrospinningpt_PT
dc.subjectWound dressingspt_PT
dc.subjectSurface functionalisationpt_PT
dc.titleElectrospun polymeric nanofibres as wound dressings: A reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleHealth Sciences Research Centre
oaire.awardTitleDevelopment of a bioactive nanofibrous membrane loaded with bioactive molecules for wound healing
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F00709%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F109563%2F2015/PT
oaire.citation.endPage71pt_PT
oaire.citation.startPage60pt_PT
oaire.citation.titleColloids and Surfaces B: Biointerfacespt_PT
oaire.citation.volume169pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPOR_CENTRO
person.familyNamePereira Miguel
person.familyNameRibeiro
person.familyNameJoaquim Sobreira Correia
person.givenNameSónia Alexandra
person.givenNameMaximiano
person.givenNameIlídio
person.identifierGX0L2QAAAAJ
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-id1A13-ABC0-C32C
person.identifier.ciencia-idBD11-6497-FD37
person.identifier.ciencia-idF610-7373-DC81
person.identifier.orcid0000-0001-7274-0399
person.identifier.orcid0000-0001-6357-8115
person.identifier.orcid0000-0003-1613-9675
person.identifier.scopus-author-id55638166400
person.identifier.scopus-author-id26658759200
person.identifier.scopus-author-id7003557499
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
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