Browsing by Author "Pacheco, Rodrigo Gabriel Rodrigues"
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- Functionalization and characterization of carbohydrates for organotriethoxysilane precursors’ synthesisPublication . Pacheco, Rodrigo Gabriel Rodrigues; Ismael, Maria Isabel Guerreiro da Costa; Nunes, Sílvia Cristina CláudioCarbohydrates are ubiquitous in all living beings, from the most complex – the humans – to the unicellular organisms. Fundamental in all kinds of biological processes, carbohydrates represent expedient candidates for biomedical applications. Through their use, countless barriers could be overcome, especially the lack of selectivity on cancer’s treatment. Although their advantages, carbohydrate synthesis is still far from completely unearthed and understood. However, the growing necessities thrust the field to more complex subjects, leading to the discovery of new potent devices capable of overwhelming the field of medicine. The same driving force pushed the field of nanotechnology to the development of new materials, with applicabilities in uncountable fields. One of these materials was the mesoporous materials, which were recently discovered, and gain major focus of research in past years. This research flows towards the creation of materials progressively more complex and organized, ultimately leading to periodic mesoporous materials. These materials can be packed with organic moieties, leading to a synergetic combination between the organic and the inorganic features. This combination conducted to the objective of this work, which can be divided in two phases. The first is synthesis of glycoside derivatives, through their functionalization, for posterior linkage to a siliceous material - in phase two - resulting in mono/di-organosilane precursors, which can be used to prepared mesoporous materials – ordered or periodic. The use of carbohydrate derivatives in combination with these materials is an innovative field, with scarce research carried, and since the synergetic combination of the organic/inorganic features, is a promising field for the development of more efficient biomedical devices, for example, drug delivery systems.