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- Characterization of the Mechanical and Biological Properties of a New Alumina ScaffoldPublication . Batista, Patrícia Sofia Pinhanços; Rodrigues, Miguel; Silva, Daniela; Morgado, Patrícia I.; Henriques, J.; Almeida, Maria; Silva, Abílio P.; Correia, Ilídio Joaquim SobreiraPurpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: the results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. the in vivo studies revealed no systemic reaction. Conclusions: the alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.