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- Prevalence and clinical features of adverse food reactions in Portuguese childrenPublication . Jorge, Arminda; Gravito-Soares, Elisa; Sarinho, Emanuel; Lorente, Felix; Gama, Jorge; Barata, Luis TabordaThe prevalence of adverse food reactions (AFR) has been increasing in the western world. Clinical manifestations are diversified and it may not be possible to clinically discriminate between IgE and non-IgE mediated AFR. In Portugal, the prevalence of AFR and food allergies in children is not known. Thus, the objectives of this study were to determine the prevalence of AFR in central Portugal.