Can Hormonal (De)regulation of Ion Transporters in Human Sertoli Cells be Responsible for Infertility?

Financiador

Organização

Publicações

Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways

Publication . Vaz, C V; Baptista, Cláudio; Marques, Ricardo; Gomes, Inês; Correia, Sara; Alves, Marco G; Cavaco, JE; Oliveira, Pedro F.; Socorro, Sílvia

Regucalcin (RGN) is a calcium (Ca(2+) )-binding protein underexpressed in prostate adenocarcinoma comparatively to non-neoplastic prostate or benign prostate hyperplasia cases. Moreover, RGN expression is negatively associated with the cellular differentiation of prostate adenocarcinoma, suggesting that loss of RGN may be associated with tumor onset and progression. However, the RGN actions over the control of prostate cell growth have not been investigated.

2014-09Artigo científico

Acesso restrito

Ver mais

Entidade financiadora

Fundação para a Ciência e a Tecnologia

Programa de financiamento

5876-PPCDTI

Número da atribuição

PTDC/QUI-BIQ/121446/2010