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Advisor(s)
Abstract(s)
This investigation provides a new strategy to impart antimicrobial properties into wool-based materials using Cecropin-B
and [Ala5]-Tritrp7 antimicrobial peptides (AMPs). The process was conducted using exhaustion method at 40 °C for
1–3 h. The presence of the AMPs in the modified-wool samples was confirmed by colorimetric assay of Bradford
reagent and possible changes in the morphology of the fibers and damage to its surface were analyzed by scanning
electron microscopy. Results showed that 1 h were long enough for the functionalization to occur effectively and that the
morphology of the fibers was not influenced by the functionalization process. Furthermore, the antimicrobial activity of
the AMPs applied on wool was assessment by JIS L 1902-2002 against Staphylococcus aureus (ATCC 6538) and
Klebsiella pneumoniae (ATCC 4352). The results showed that both AMPs have a high reduction in bacterial growth
(Cecropin-B resulting in 71.67% reduction against S. aureus and 85.95% against K. pneumoniae. While [Ala5]-Tritrp7
resulting in 66.74% reduction against S. aureus and 88.65% against K. pneumoniae).
Description
Keywords
Wool-based materials Antimicrobial-textiles Antimicrobial-peptides Antimicrobial-agents
Citation
Cláudia Mouro & Isabel C. Gouveia (2016) Antimicrobial functionalization of wool: assessment of the effect of Cecropin-B and [Ala5]-Tritrp7 antimicrobial peptides, The Journal of The Textile Institute, 107:12, 1575-1583, DOI: 10.1080/00405000.2015.1130297