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IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies

2018-03-13Journal article Restricted access
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dc.contributor.authorAlves, Cátia
dc.contributor.authorSousa, Ana Rita Lima
dc.contributor.authorDiogo, Duarte Miguel de Melo
dc.contributor.authorCorreia, Ilídio Joaquim Sobreira
dc.date.accessioned2018-03-22T10:26:58Z
dc.date.available2018-03-22T10:26:58Z
dc.date.issued2018-03-13
dc.description.abstractIR780, a molecule with a strong optical absorption and emission in the near infrared (NIR) region, is receiving an increasing attention from researchers working in the area of cancer treatment and imaging. Upon irradiation with NIR light, IR780 can produce reactive oxygen species as well as increase the body temperature, thus being a promising agent for application in cancer photodynamic and photothermal therapy. However, IR780’s poor water solubility, fast clearance, acute toxicity and low tumor uptake may limit its use. To overcome such issues, several types of nanomaterials have been used to encapsulate and deliver IR780 to tumor cells. This mini-review is focused on the application of IR780 based nanostructures for cancer imaging, and photothermal, photodynamic and combinatorial therapies.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAlves, C.G., Lima-Sousa, R., de Melo-Diogo, D., Louro, R.O., Correia I.J. (2018) “IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies” International Journal of Pharmaceutics, Vol. 542, pp.164-175pt_PT
dc.identifier.doi10.1016/j.ijpharm.2018.03.020pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/4708
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationHealth Sciences Research Centre
dc.relationMULTIFUNCTIONAL GRAPHENE-OXIDE NANOCARRIERS FOR DRUG DELIVERY AND PHOTOTHERMAL THERAPY OF LUNG CANCER
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0378517318301674pt_PT
dc.subjectCancerpt_PT
dc.subjectCombinatorial therapypt_PT
dc.subjectImagingpt_PT
dc.subjectR780pt_PT
dc.subjectPhotodynamic therapypt_PT
dc.subjectPhotothermal therapypt_PT
dc.titleIR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapiespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleHealth Sciences Research Centre
oaire.awardTitleMULTIFUNCTIONAL GRAPHENE-OXIDE NANOCARRIERS FOR DRUG DELIVERY AND PHOTOTHERMAL THERAPY OF LUNG CANCER
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F00709%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F103506%2F2014/PT
oaire.citation.endPage164pt_PT
oaire.citation.issue175pt_PT
oaire.citation.titleInternational Journal of Pharmaceuticspt_PT
oaire.citation.volume542pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameAlves
person.familyNameSousa
person.familyNameMiguel de Melo Diogo
person.familyNameJoaquim Sobreira Correia
person.givenNameCátia Gomes
person.givenNameAna Rita Lima
person.givenNameDuarte
person.givenNameIlídio
person.identifierC2z5x04AAAAJ
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-id8317-7EF2-24C8
person.identifier.ciencia-idBD19-68AA-7099
person.identifier.ciencia-id9C10-9BD8-634E
person.identifier.ciencia-idF610-7373-DC81
person.identifier.orcid0000-0001-7066-3051
person.identifier.orcid0000-0003-4764-1967
person.identifier.orcid0000-0001-9984-3603
person.identifier.orcid0000-0003-1613-9675
person.identifier.ridB-1125-2019
person.identifier.scopus-author-id57201213407
person.identifier.scopus-author-id57201215315
person.identifier.scopus-author-id56266511300
person.identifier.scopus-author-id7003557499
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
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