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Prevalence Of Potentially Inappropriate Medication In The Older Adult Population Within Primary Care In Portugal: A Nationwide Cross-Sectional Study

2019-09-19Journal article Open access
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dc.contributor.authorSimões, Pedro Augusto Gomes Rodrigues Marques
dc.contributor.authorSantiago, Luiz Miguel de Mendonça Soares
dc.contributor.authorMaurício, Katia
dc.contributor.authorSimões, José Augusto Rodrigues
dc.date.accessioned2019-09-23T08:31:34Z
dc.date.available2019-09-23T08:31:34Z
dc.date.issued2019-09-19
dc.description.abstractBackground: In potentially inappropriate medications harm potentially outweighs benefits. Even appropriately prescribed medications may become inappropriate. They can lead to a high risk of adverse drug reactions, morbidity and mortality. The aim of this study was to determine the prevalence of potentially inappropriate medication in the older adult population attending primary care in Portugal and to identify associated sociodemographic and clinical factors. Methods: We conducted a cross-sectional, analytical study in primary care centres from the five Portuguese healthcare administrative regions and the two autonomous regions. We used a random sample of 757 older patients provided by the information department of the ministry of health (SPMS) and family doctors from the autonomous regions. Data collection occurred March 2018 and we studied sociodemographic characteristics, clinical profile and medication. We used 2015 Beers Criteria to assess potentially inappropriate medications. Logistic regression analyses were performed to determine associations between potentially inappropriate medications’ prescriptions and other variables. Results: Potentially inappropriate medication was present in 68.6% and 46.1% of the sample had two or more. The likelihood of having potentially inappropriate medication increased significantly with being female (OR=1.56 [1.05 to 2.31]), number of chronic health problems (OR=1.06 [1.01 to 1.13]), number of pharmacological subclasses (OR=1.40 [1.30 to 1.51]) and number of prescribers (OR=1.34 [1.09 to 1.65]). Proton-pump inhibitors, nonsteroidal anti-inflammatory drugs and benzodiazepines were the most commonly found ones. Conclusion: Potentially inappropriate medication in older adults was found to be a common occurrence in Portugal. It is important that doctors are aware of this problem, namely in the primary care setting due to the longitudinal care.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPrevalence Of Potentially Inappropriate Medication In The Older Adult Population Within Primary Care In Portugal: A Nationwide Cross-Sectional Study. Patient Preference and Adherence. 2019; 13: 1569-76.pt_PT
dc.identifier.doi10.2147/PPA.S219346pt_PT
dc.identifier.issn1177-889X
dc.identifier.urihttp://hdl.handle.net/10400.6/7216
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherDovepresspt_PT
dc.relation.publisherversionhttps://www.dovepress.com/articles.php?article_id=48693pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectPotentially inappropriate medicationpt_PT
dc.subjectAgedpt_PT
dc.subjectPolypharmacypt_PT
dc.subjectMultimorbiditypt_PT
dc.titlePrevalence Of Potentially Inappropriate Medication In The Older Adult Population Within Primary Care In Portugal: A Nationwide Cross-Sectional Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1576pt_PT
oaire.citation.startPage1569pt_PT
oaire.citation.titlePatient Preference and Adherencept_PT
oaire.citation.volume13pt_PT
person.familyNameSimões
person.familyNameSantiago
person.familyNameRodrigues Simões
person.givenNamePedro Augusto
person.givenNameLuiz Miguel
person.givenNameJosé Augusto
person.identifierL-4695-2016
person.identifier.ciencia-id5111-BB0F-F1F2
person.identifier.ciencia-idAB13-2946-9E61
person.identifier.ciencia-idE419-CED2-38BA
person.identifier.orcid0000-0003-4692-2003
person.identifier.orcid0000-0002-9343-2827
person.identifier.orcid0000-0003-2264-7086
person.identifier.ridO-3955-2017
person.identifier.ridP-9545-2018
person.identifier.scopus-author-id36896116500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication10fb5c22-b65f-4890-ae07-234f5a8b0a18
relation.isAuthorOfPublicationd369cbf1-cade-4706-8910-63a567b6e838
relation.isAuthorOfPublication919b504d-aaa9-40ee-a1a5-40e1e0a57f6f
relation.isAuthorOfPublication.latestForDiscovery10fb5c22-b65f-4890-ae07-234f5a8b0a18

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