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2019 ARIA Care pathways for allergen immunotherapy

2019-11Journal article Open access
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dc.contributor.authorBousquet, Jean
dc.contributor.authorPfaar, Oliver
dc.contributor.authorTogias, Alkis
dc.contributor.authorSchünemann, Holger J
dc.contributor.authorAnsotegui, Ignacio
dc.contributor.authorPapadopoulos, Nikolaos G
dc.contributor.authorTsiligianni, Ioanna
dc.contributor.authorAgache, Ioana
dc.contributor.authorAnto, Josep M.
dc.contributor.authorBachert, Claus
dc.contributor.authorBedbrook, Anna
dc.contributor.authorBergmann, Karl-Christian
dc.contributor.authorBosnic-Anticevich, Sinthia
dc.contributor.authorBosse, Isabelle
dc.contributor.authorBrozek, Jan
dc.contributor.authorCalderon, Moises A
dc.contributor.authorCanonica, Giorgio W
dc.contributor.authorCaraballo, Luigi
dc.contributor.authorCardona, Victoria
dc.contributor.authorCasale, Thomas
dc.contributor.authorCecchi, Lorenzo
dc.contributor.authorChu, Derek
dc.contributor.authorCosta, Elísio
dc.contributor.authorCruz, Alvaro A
dc.contributor.authorCzarlewski, Wienczyslawa
dc.contributor.authorDurham, Stephen R
dc.contributor.authorDu Toit, George
dc.contributor.authorDykewicz, Mark
dc.contributor.authorEbisawa, Motohiro
dc.contributor.authorFauquert, Jean Luc
dc.contributor.authorFernandez-Rivas, Montserrat
dc.contributor.authorFokkens, Wytske J
dc.contributor.authorFonseca, João
dc.contributor.authorFontaine, Jean-François
dc.contributor.authorGerth van Wijk, Roy
dc.contributor.authorHaahtela, Tari
dc.contributor.authorHalken, Susanne
dc.contributor.authorHellings, Peter
dc.contributor.authorIerodiakonou, Despo
dc.contributor.authorIinuma, Tomohisa
dc.contributor.authorIvancevich, Juan Carlos
dc.contributor.authorJacobsen, Lars
dc.contributor.authorJutel, Marek
dc.contributor.authorKaidashev, Igor
dc.contributor.authorKhaitov, Musa
dc.contributor.authorKalayci, Omer
dc.contributor.authorKleine Tebbe, Jörg
dc.contributor.authorKlimek, Ludger
dc.contributor.authorKowalski, Marek L
dc.contributor.authorKuna, Piotr
dc.contributor.authorKvedarienė, Violeta
dc.contributor.authorLa Grutta, Stefania
dc.contributor.authorLarenas Linnemann, Désirée
dc.contributor.authorLau, Susanne
dc.contributor.authorLaune, Daniel
dc.contributor.authorLe Thi Tuyet, Lan
dc.contributor.authorLodrup Carlsen, Karin
dc.contributor.authorLourenço, Olga
dc.contributor.authorMalling, Hans-Jørgen
dc.contributor.authorMarien, Gert
dc.contributor.authorMenditto, Enrica
dc.contributor.authorMercier, Gregoire
dc.contributor.authorMullol, Joaquim
dc.contributor.authorMuraro, Antonella
dc.contributor.authorO'Hehir, Robyn
dc.contributor.authorOkamoto, Yoshitaka
dc.contributor.authorPajno, Giovanni B
dc.contributor.authorPark, Hae-Sim
dc.contributor.authorPanzner, Petr
dc.contributor.authorPassalacqua, Giovanni
dc.contributor.authorPham-Thi, Nhan
dc.contributor.authorRoberts, Graham
dc.contributor.authorPawankar, Ruby
dc.contributor.authorRolland, Christine
dc.contributor.authorRosario, Nelson
dc.contributor.authorRyan, Dermot
dc.contributor.authorSamolinski, Boleslaw
dc.contributor.authorSanchez-Borges, Mario
dc.contributor.authorScadding, Glenis
dc.contributor.authorShamji, Mohamed H
dc.contributor.authorSheikh, Aziz
dc.contributor.authorSturm, Gunter J
dc.contributor.authorTodo-Bom, Ana
dc.contributor.authorToppila-Salmi, Sanna
dc.contributor.authorValentin Rostan, Marylin
dc.contributor.authorValiulis, Arunas
dc.contributor.authorValovirta, Erkka
dc.contributor.authorVentura, Maria Teresa
dc.contributor.authorWahn, Ulrich
dc.contributor.authorWalker, Samantha
dc.contributor.authorWallace, Dana
dc.contributor.authorWaserman, Susan
dc.contributor.authorYorgancioglu, Arzu
dc.contributor.authorZuberbier, Torsten
dc.date.accessioned2020-02-19T11:37:26Z
dc.date.available2020-02-19T11:37:26Z
dc.date.issued2019-11
dc.description.abstractAllergen immunotherapy (AIT) is a proven therapeutic option for the treatment of allergic rhinitis and/or asthma. Many guidelines or national practice guidelines have been produced but the evidence-based method varies, many are complex and none propose care pathways. This paper reviews care pathways for AIT using strict criteria and provides simple recommendations that can be used by all stakeholders including healthcare professionals. The decision to prescribe AIT for the patient should be individualized and based on the relevance of the allergens, the persistence of symptoms despite appropriate medications according to guidelines as well as the availability of good-quality and efficacious extracts. Allergen extracts cannot be regarded as generics. Immunotherapy is selected by specialists for stratified patients. There are no currently available validated biomarkers that can predict AIT success. In adolescents and adults, AIT should be reserved for patients with moderate/severe rhinitis or for those with moderate asthma who, despite appropriate pharmacotherapy and adherence, continue to exhibit exacerbations that appear to be related to allergen exposure, except in some specific cases. Immunotherapy may be even more advantageous in patients with multimorbidity. In children, AIT may prevent asthma onset in patients with rhinitis. mHealth tools are promising for the stratification and follow-up of patients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1111/all.13805pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/9362
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectAllergen immunotherapypt_PT
dc.subjectAsthmapt_PT
dc.subjectRhinitispt_PT
dc.subjectChildrenpt_PT
dc.subjectStratificationpt_PT
dc.subjectmHealthpt_PT
dc.title2019 ARIA Care pathways for allergen immunotherapypt_PT
dc.title.alternativeMany guidelines or national practice guidelines have been produced but many are complex and none propose care pathwayspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2102pt_PT
oaire.citation.issue11pt_PT
oaire.citation.startPage2087pt_PT
oaire.citation.titleAllergypt_PT
oaire.citation.volume74pt_PT
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