Repository logo
 
Publication

Synthesis and characterization of a photocrosslinkable chitosan–gelatin hydrogel aimed for tissue regeneration

2015-07-24Journal article Restricted access
Simple item page
dc.contributor.authorSaraiva, Sofia Mendes
dc.contributor.authorMiguel, Sónia P.
dc.contributor.authorRibeiro, MP.
dc.contributor.authorCoutinho, Paula Isabel Teixeira Gonçalves
dc.contributor.authorCorreia, Ilídio Joaquim Sobreira
dc.date.accessioned2018-03-21T09:42:10Z
dc.date.available2018-03-21T09:42:10Z
dc.date.issued2015-07-24
dc.description.abstractIn the area of tissue engineering different approaches have been studied, so far, for promoting regeneration or replacement of damaged tissues. Among the different materials developed, hydrogels, due to their biocompatibility and similarities with the native extracellular matrix, have emerged as suitable candidates for being used for different therapeutic purposes. Herein, photocrosslinkable hydrogels, composed by chitosan methacrylamide (ChMA) and gelatin methacrylamide (GelMA) were crosslinked by ultraviolet (UV) light, using Irgacue 2959 as photoinitiator. The morphological, physicochemical and biological properties of the hydrogels were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy and nuclear magnetic resonance. The obtained results demonstrated that the developed hydrogels possess suitable properties for being used as 3D constructs on several areas of tissue engineering. Furthermore, these properties may allow their future application as space filling agents or as delivery vehicles of bioactive molecules and cells.pt_PT
dc.description.sponsorshipSónia P. Miguel acknowledges a fellowship from CENTRO-07- ST24-FEDER 002012, CENTRO-07-ST24-FEDER 002014 and CENTRO-07-ST24-FEDER 002015 financed by Programa Operacional Regional do Centro 2007–2013 QREN (Programa “Mais Centro”)
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSaraiva, S.M., Miguel, S.P., Ribeiro, M. P., Coutinho, P. e Correia, I.J. (2015) “Synthesis and characterization of a photocrosslinkable chitosan-gelatin hydrogel aimed for tissue regeneration”, RSC Advances, Vol.5, pp. 63478-63488pt_PT
dc.identifier.doi10.1039/C5RA10638Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/4676
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherRoyal Society of Chemistrypt_PT
dc.relation.publisherversionhttp://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra10638a#!divAbstractpt_PT
dc.subjectChitosanpt_PT
dc.subjectGelatinpt_PT
dc.subjectHydrogelpt_PT
dc.titleSynthesis and characterization of a photocrosslinkable chitosan–gelatin hydrogel aimed for tissue regenerationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage63488pt_PT
oaire.citation.startPage63478pt_PT
oaire.citation.titleRSC Advancespt_PT
oaire.citation.volume5pt_PT
person.familyNameMENDES SARAIVA
person.familyNamePereira Miguel
person.familyNameRibeiro
person.familyNameJoaquim Sobreira Correia
person.givenNameSOFIA
person.givenNameSónia Alexandra
person.givenNameMaximiano
person.givenNameIlídio
person.identifierAAY-1488-2021
person.identifierGX0L2QAAAAJ
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-id3511-F6AC-06F0
person.identifier.ciencia-id1A13-ABC0-C32C
person.identifier.ciencia-idBD11-6497-FD37
person.identifier.ciencia-idF610-7373-DC81
person.identifier.orcid0000-0001-8849-804X
person.identifier.orcid0000-0001-7274-0399
person.identifier.orcid0000-0001-6357-8115
person.identifier.orcid0000-0003-1613-9675
person.identifier.scopus-author-id57193545165
person.identifier.scopus-author-id55638166400
person.identifier.scopus-author-id26658759200
person.identifier.scopus-author-id7003557499
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationb32823c3-1177-4a06-99b8-392339ab6477
relation.isAuthorOfPublication3956033a-4abf-439b-a4fd-25c5bd9d8e7a
relation.isAuthorOfPublication3fe7a59f-e867-4bed-bb6e-7d7631330af5
relation.isAuthorOfPublicationf2c3e779-34a2-4309-950a-80687664c6ad
relation.isAuthorOfPublication.latestForDiscovery3fe7a59f-e867-4bed-bb6e-7d7631330af5

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
2015 Saraiva RSC Advances.pdf
Size:
1.7 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

FCS - DCM | Documentos por Auto-Depósito