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Oral and Gastric Helicobacter Pylori: Effects and Associations

dc.contributor.authorVeiga, Nélio Jorge
dc.contributor.authorPereira, Carlos
dc.contributor.authorResende, Carlos
dc.contributor.authorAmaral, Odete
dc.contributor.authorFerreira, Manuela
dc.contributor.authorNelas, Paula
dc.contributor.authorChaves, Claudia
dc.contributor.authorDuarte, João
dc.contributor.authorCirnes, Luís
dc.contributor.authorMachado, José Carlos
dc.contributor.authorFerreira, Paula
dc.contributor.authorCorreia, Ilídio Joaquim Sobreira
dc.date.accessioned2018-03-20T16:47:18Z
dc.date.available2018-03-20T16:47:18Z
dc.date.issued2015-05-26
dc.description.abstractIntroduction This study consisted in the comparison of the prevalence of Helicobacter pylori (H. pylori) present in the stomach and in saliva of a sample of Portuguese adolescents and the assessment of the association between H. pylori infection with socio-demographic variables and prevalence of dental caries. Materials and Methods A cross-sectional study was designed including a sample of 447 adolescents aged 12 to 19 years old, attending a public school in Sátão, Portugal. A questionnaire about socio-demographic variables and oral health behaviors was applied. Gastric H. pylori infection was determined using the urease breath test (UBT). Saliva collection was obtained and DNA was extracted by Polymerase Chain Reaction (PCR) in order to detect the presence of oral H. pylori. Results The prevalence of gastric H. pylori detected by UBT was 35.9%. Within the adolescents with a gastric UBT positive, only 1.9% were positive for oral H. pylori. The presence of gastric H. pylori was found to be associated with age (>15years, Odds ratio (OR)=1.64,95%CI=1.08-2.52), residence area (urban,OR=1.48,95%CI=1.03-2.29) and parents´ professional situation (unemployed,OR=1.22,95%CI=1.02-1.23). Among those with detected dental caries during the intra-oral observation, 37.4% were positive for gastric H. pylori and 40.2% negative for the same bacterial strain (p=0.3). Conclusions The oral cavity cannot be considered a reservoir for infection of H. pylori. Gastric H. pylori infection was found to be associated with socio-demographic variables such as age, residence area and socioeconomic status.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationVeiga, N., Pereira, C., Resende, C, Amaral, O., Ferreira, M., Nelas, P., Chaves, C., Duarte, J., Cirnes, L., Machado, J.L., Ferreira, P. e Correia, I.J. (2015) "Oral and gastric Helicobacter pylori: effects and associations". Plos one, 10(5): e0126923pt_PT
dc.identifier.doi10.1371/journal.pone.0126923pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/4669
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherPLOSpt_PT
dc.relation.publisherversionhttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126923pt_PT
dc.subjectHelicobacter Pyloript_PT
dc.subjectDental cariespt_PT
dc.titleOral and Gastric Helicobacter Pylori: Effects and Associationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPagee0126923pt_PT
oaire.citation.titlePLOS ONEpt_PT
oaire.citation.volume10pt_PT
person.familyNameVeiga
person.familyNameResende
person.familyNameAmaral
person.familyNameAndrade Batista Nelas
person.familyNameCorreia Balula Chaves
person.familyNameDuarte
person.familyNameCirnes
person.familyNameLemos Machado
person.familyNameCristina Nunes Ferreira Calvinho
person.familyNameJoaquim Sobreira Correia
person.givenNameNélio
person.givenNameCarlos
person.givenNameOdete
person.givenNamePaula Alexandra
person.givenNameCláudia Margarida
person.givenNameJoão
person.givenNameLuís
person.givenNameJosé Carlos
person.givenNamePaula
person.givenNameIlídio
person.identifierE-9556-2018
person.identifierC-5907-2009
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person.identifier.ciencia-id421A-03F3-B261
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person.identifier.ciencia-idF610-7373-DC81
person.identifier.orcid0000-0001-6288-0435
person.identifier.orcid0000-0001-7143-7099
person.identifier.orcid0000-0002-3382-6074
person.identifier.orcid0000-0003-0043-3597
person.identifier.orcid0000-0002-8103-7221
person.identifier.orcid0000-0002-2348-5878
person.identifier.orcid0000-0003-4741-8415
person.identifier.orcid0000-0003-3393-4427
person.identifier.orcid0000-0003-1613-9675
person.identifier.scopus-author-id54794730000
person.identifier.scopus-author-id7102792651
person.identifier.scopus-author-id55321888200
person.identifier.scopus-author-id7003557499
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
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