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Association between berries intake and cardiovascular diseases risk factors: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials

2018-02-21Journal article Restricted access
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dc.contributor.authorLuís, Ângelo
dc.contributor.authorDomingues, F.C.
dc.contributor.authorPereira, L.
dc.date.accessioned2020-01-28T14:09:07Z
dc.date.available2020-01-28T14:09:07Z
dc.date.issued2018-02-21
dc.description.abstractThe main goal of this work was to clarify the effects of the consumption of berries on cardiovascular disease (CVD) risk factors by performing a systematic review according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) statement, followed by a meta-analysis and a trial sequential analysis (TSA) of randomized controlled trials (RCTs). The electronic search was conducted in PubMed, Scopus, SciELO, Web of Science and Cochrane Library between April and June 2016. To be included, RCTs had to report 1 or more of the following outcomes: total cholesterol (TC), HDL-cholesterol (HDL), LDL-cholesterol (LDL), triglycerides (TG), blood pressure (BP), C-reactive protein (CRP), tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6), vascular cell adhesion molecule-1 (VCAM), intercellular adhesion molecule-1 (ICAM), glucose, insulin, apolipoprotein A-I (Apo A-I) or apolipoprotein B (Apo B). It was observed that the intake of berries reduces TC, LDL, TG, and BP while increasing the level of HDL, suggesting a beneficial effect on the control of CVDs' risk factors. Thus, the intake of berries as nutraceuticals or functional foods could be suggested for the prevention and control of CVDs.pt_PT
dc.description.sponsorshipSantander/Totta with the reference BIPD/ICI-FC-BST-UBI 2016.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1039/c7fo01551hpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/8808
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectCardiovascular Diseasespt_PT
dc.subjectFruitpt_PT
dc.subjectHumanspt_PT
dc.subjectRandomized Controlled Trials as Topicpt_PT
dc.subjectRisk Factorspt_PT
dc.titleAssociation between berries intake and cardiovascular diseases risk factors: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trialspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage757pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage740pt_PT
oaire.citation.titleFood and Functionpt_PT
oaire.citation.volume9pt_PT
person.familyNameSantos Luís
person.familyNameDomingues
person.familyNamePereira
person.givenNameÂngelo Filipe
person.givenNameFernanda
person.givenNameLuísa
person.identifier.ciencia-id3D14-798B-65D3
person.identifier.ciencia-id6514-0498-3E8F
person.identifier.ciencia-id4F15-1868-D001
person.identifier.orcid0000-0003-0712-6522
person.identifier.orcid0000-0002-9540-0853
person.identifier.orcid0000-0002-9068-4607
person.identifier.ridN-7295-2013
person.identifier.scopus-author-id10139481400
person.identifier.scopus-author-id10839238300
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa2d7c872-99db-41e1-9bc9-82c2d47b4661
relation.isAuthorOfPublication8d5fe6e2-21af-4557-9c46-84103254a18a
relation.isAuthorOfPublication604e508e-9f4e-4950-b2a4-1b06c7192afe
relation.isAuthorOfPublication.latestForDiscoverya2d7c872-99db-41e1-9bc9-82c2d47b4661

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