Publication
Poly(2-ethyl-2-oxazoline)–IR780 conjugate nanoparticles for breast cancer phototherapy
dc.contributor.author | Alves, Cátia | |
dc.contributor.author | Lima-Sousa, Rita | |
dc.contributor.author | Melo, Bruna L. | |
dc.contributor.author | Ferreira, Paula | |
dc.contributor.author | Moreira, André | |
dc.contributor.author | Correia, I.J. | |
dc.contributor.author | de Melo-Diogo, Duarte | |
dc.date.accessioned | 2023-06-12T09:51:09Z | |
dc.date.embargo | 2025-06-09 | |
dc.date.issued | 2023-02-21 | |
dc.description.abstract | Conventional anticancer approaches are often associated with severe side effects. Herein, the authors assembled a novel nanoparticle whose therapeutic effect is triggered by laser light. In in vitro assays, the produced nanomaterial was able to, after interacting with laser light, reduce the viability of classic and advanced cancer models. In these conditions, but in the absence of laser light, no cytotoxicity was observed. In this way, the on-demand effect (triggered by laser light) may contribute to reduced side effects. Moreover, the produced nanoparticle revealed good stability, which is important for its future translation. | pt_PT |
dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
dc.identifier.doi | 10.2217/nnm-2022-0218 | pt_PT |
dc.identifier.issn | 1743-5889 | |
dc.identifier.uri | http://hdl.handle.net/10400.6/13354 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.publisher | Future medicine | pt_PT |
dc.relation | Health Sciences Research Centre | |
dc.relation | Health Sciences Research Centre | |
dc.relation | Silk Sericin as an industrial wastewater with valuable biomedical potential | |
dc.relation | Shear-thinning and self-healing hydrogels: tuning the polymer-related features for the tumor confined delivery of therapeutics aimed for metastatic breast cancer immuno-photothermal therapy | |
dc.relation | Development of a responsive multi-layer microneedle patch for the sequential PTT/PDT and immunotherapy of invasive breast cancer | |
dc.relation | Injectable in situ forming graphene-based hydrogels for double immune checkpoint inhibitor photothermal therapy | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
dc.subject | Cancer | pt_PT |
dc.subject | Photothermal therapy | pt_PT |
dc.subject | Poly(2-ethyl-2-oxazoline) | pt_PT |
dc.subject | Polymer–IR780 conjugate | pt_PT |
dc.subject | Spheroids | pt_PT |
dc.title | Poly(2-ethyl-2-oxazoline)–IR780 conjugate nanoparticles for breast cancer phototherapy | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.awardTitle | Health Sciences Research Centre | |
oaire.awardTitle | Health Sciences Research Centre | |
oaire.awardTitle | Silk Sericin as an industrial wastewater with valuable biomedical potential | |
oaire.awardTitle | Shear-thinning and self-healing hydrogels: tuning the polymer-related features for the tumor confined delivery of therapeutics aimed for metastatic breast cancer immuno-photothermal therapy | |
oaire.awardTitle | Development of a responsive multi-layer microneedle patch for the sequential PTT/PDT and immunotherapy of invasive breast cancer | |
oaire.awardTitle | Injectable in situ forming graphene-based hydrogels for double immune checkpoint inhibitor photothermal therapy | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00709%2F2020/PT | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00709%2F2020/PT | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FBTA-BTA%2F0696%2F2020/PT | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/CEEC IND4ed/2021.00590.CEECIND%2FCP1661%2FCT0001/PT | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F145386%2F2019/PT | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F144922%2F2019/PT | |
oaire.awardURI | info:eu-repo/grantAgreement/FCT/POR_CENTRO/2021.06044.BD/PT | |
oaire.citation.conferencePlace | UK | pt_PT |
oaire.citation.endPage | 2072 | pt_PT |
oaire.citation.issue | 27 | pt_PT |
oaire.citation.startPage | 2057 | pt_PT |
oaire.citation.title | Nanomedicine | pt_PT |
oaire.citation.volume | 17 | pt_PT |
oaire.fundingStream | 6817 - DCRRNI ID | |
oaire.fundingStream | 6817 - DCRRNI ID | |
oaire.fundingStream | 3599-PPCDT | |
oaire.fundingStream | CEEC IND4ed | |
oaire.fundingStream | POR_CENTRO | |
oaire.fundingStream | POR_CENTRO | |
oaire.fundingStream | POR_CENTRO | |
person.familyName | Alves | |
person.familyName | Sousa | |
person.familyName | Lopes Melo | |
person.familyName | Cristina Nunes Ferreira Calvinho | |
person.familyName | Moreira | |
person.familyName | Joaquim Sobreira Correia | |
person.familyName | Miguel de Melo Diogo | |
person.givenName | Cátia Gomes | |
person.givenName | Ana Rita Lima | |
person.givenName | Bruna Daniela | |
person.givenName | Paula | |
person.givenName | André Ferreira | |
person.givenName | Ilídio | |
person.givenName | Duarte | |
person.identifier | 1161643 | |
person.identifier | UMbJ1KMAAAAJ | |
person.identifier | C2z5x04AAAAJ | |
person.identifier.ciencia-id | 8317-7EF2-24C8 | |
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person.identifier.ciencia-id | 9C10-9BD8-634E | |
person.identifier.orcid | 0000-0001-7066-3051 | |
person.identifier.orcid | 0000-0003-4764-1967 | |
person.identifier.orcid | 0000-0002-0078-1877 | |
person.identifier.orcid | 0000-0003-3393-4427 | |
person.identifier.orcid | 0000-0002-0604-2506 | |
person.identifier.orcid | 0000-0003-1613-9675 | |
person.identifier.orcid | 0000-0001-9984-3603 | |
person.identifier.rid | B-1125-2019 | |
person.identifier.scopus-author-id | 57201213407 | |
person.identifier.scopus-author-id | 57201215315 | |
person.identifier.scopus-author-id | 55321888200 | |
person.identifier.scopus-author-id | 56401521300 | |
person.identifier.scopus-author-id | 7003557499 | |
person.identifier.scopus-author-id | 56266511300 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.identifier | http://doi.org/10.13039/501100001871 | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
project.funder.name | Fundação para a Ciência e a Tecnologia | |
rcaap.embargofct | Os direitos da publicação foram cedidos à editora | pt_PT |
rcaap.rights | embargoedAccess | pt_PT |
rcaap.type | article | pt_PT |
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