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Asymmetric membranes as ideal wound dressings: An overview on production methods, structure, properties and performance relationship

dc.contributor.authorMorgado, Patrícia I.
dc.contributor.authorRicardo, Ana Aguiar
dc.contributor.authorCorreia, I.J.
dc.date.accessioned2018-03-21T09:11:35Z
dc.date.available2018-03-21T09:11:35Z
dc.date.issued2015-04-25
dc.description.abstractHealing a wound is a process that comprises sequential steps aimed to restore the structure and function of damaged cells and tissues. Since the antiquity, to promote an effective wound healing, different materials have been used to cover the wound. Nowadays, dressings that are able to mimic the structure and composition of skin are specifically designed to exhibit several required functions. To cope with this demand, different wound dressings have been produced using conventional techniques, during the last two decades. Among them, asymmetric ones present a dense top layer to protect the wound from physical damage and pathogen penetration and an inner porous layer that allows the exudates absorption, keeping the moisturized environment needed for effective skin regeneration. However, the production methods used so far, wet- and dry/wet-phase inversion techniques, present some limitations such as the use of toxic organic solvents, the lack of polymers variety and are very time-consuming. In addition, taking into account the worldwide economic status, sustainable procedures, like supercritical carbon dioxide (scCO2) – assisted phase inversion and electrospinning techniques can be adopted to produce suitable dressings for wound-management. Herein, a critical review of the methods used to produce asymmetric membranes is presented, highlighting the different properties that can be enhanced for wound healing purposes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMorgado, P.I., Aguiar-Ricardo A. e Correia, I.J. (2015) "Asymmetric membranes as ideal wound dressings: An overview on production methods, structure, properties and performance relationship", Journal of Membrane Science, Vol. 490, pp. 139-151pt_PT
dc.identifier.doi10.1016/j.memsci.2015.04.064pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/4671
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
dc.relationDEVELOPMENT OF HYDROGELS LOADED WITH MICROPARTICLES CONTAINING CELLS AND BIOMOLECULES FOR SKIN REGENERATION
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0376738815003956pt_PT
dc.subjectAsymmetrical membranespt_PT
dc.subjectWet and dry/wet techniquespt_PT
dc.subjectSupercritical CO2pt_PT
dc.subjectElectrospinningpt_PT
dc.subjectWound dressingspt_PT
dc.titleAsymmetric membranes as ideal wound dressings: An overview on production methods, structure, properties and performance relationshippt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
oaire.awardTitleDEVELOPMENT OF HYDROGELS LOADED WITH MICROPARTICLES CONTAINING CELLS AND BIOMOLECULES FOR SKIN REGENERATION
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FQUI%2F50006%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F80648%2F2011/PT
oaire.citation.endPage151pt_PT
oaire.citation.startPage139pt_PT
oaire.citation.titleJournal of Membrane Sciencept_PT
oaire.citation.volume490pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameDa Cruz Morgado Ferreira
person.familyNameAguiar-Ricardo
person.familyNameJoaquim Sobreira Correia
person.givenNamePatrícia Isabel
person.givenNameAna
person.givenNameIlídio
person.identifier239073
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-idE71C-3D0E-821B
person.identifier.ciencia-id2C1A-9947-19BA
person.identifier.ciencia-idF610-7373-DC81
person.identifier.orcid0000-0002-1005-9853
person.identifier.orcid0000-0002-2193-1440
person.identifier.orcid0000-0003-1613-9675
person.identifier.ridC-3286-2011
person.identifier.scopus-author-id6602194100
person.identifier.scopus-author-id7003557499
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
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