| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 263.69 KB | Adobe PDF |
Advisor(s)
Abstract(s)
The affinity of four 3-aminomethyltetralones for 5-HT2 receptors is reported, together with their inhibitory activity against serotonin-induced contractions in rat aorta rings stripped of endothelium. Compound 4, which has a p-fluorobenzoyl-piperidine fragment, exhibited activity similar to that of methysergyde.