Publication
In Vitro Antioxidant Activity and Total Phenolic Content of Root Extracts from Phragmanthera glaucocarpa (Peyr.) Balle
| dc.contributor.author | Fernandes, Nélson | |
| dc.contributor.author | Canelo, Laura Isabel Nave | |
| dc.contributor.author | Mata, Rosalina da Conceição dos Santos | |
| dc.contributor.author | Mendonca, Dina | |
| dc.contributor.author | Mendonça, António | |
| dc.date.accessioned | 2019-01-30T09:24:29Z | |
| dc.date.available | 2019-01-30T09:24:29Z | |
| dc.date.issued | 2018-12-01 | |
| dc.description.abstract | Background: Africa has a rich diversity of plant species, which can be considered important sources of new chemical compounds that can be used in the development of novel therapeutic drugs. Objectives: The present study aimed at investigating the antioxidant activity and total phenolic content of extracts obtained from the roots of Phragmanthera glaucocarpa (Peyr.) Balle, a plant used in Angola folk medicine. Methods: The prepared extracts were tested for their antioxidant activity using ABTS (2,2’-azinobis-(3-ethyl-benzothiazoline-6-sulfonic acid), DPPH (1’,1’-diphenyl-2-picrylhydrazyl), and peroxide value methods. Total phenolics were evaluated by the FolinCiocalteu method. Results: For ABTS, the best EC50 result was obtained with the ethyl acetate fraction (1.06 ± 0.30 mg/mL). For the DPPH method, the methanol extract and aqueous fraction presented the best EC50 results, 0.10 ± 0.01 mg/mL and 0.10 ± 0.00 mg/mL, respectively. The ethyl acetate fraction had the highest phenolic content (280.42 ± 0.15 mg G.A.E. /g of dry extract). The best result for the peroxide reduction value on the eighth day of sunflower oil oxidation was obtained for the aqueous fraction, with 131.40 ± 1.05 meq O2 /g of lipid sample. Conclusions: The results of the present study demonstrate that the roots of the medicinal plant Phragmanthera glaucocarpa (Peyr.) Balle represent a promising source of natural phenolic compounds with antioxidant activity. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.5812/jjnpp.62238 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.6/6860 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.relation.ispartofseries | 4; | |
| dc.relation.publisherversion | http://jjnpp.com/en/articles/62238.html | pt_PT |
| dc.subject | Phenolic Compounds | pt_PT |
| dc.subject | DPPH | pt_PT |
| dc.subject | ABTS | pt_PT |
| dc.subject | Peroxide Value | pt_PT |
| dc.subject | Folin-Ciocalteu | pt_PT |
| dc.subject | Phragmanthera glaucocarpa | pt_PT |
| dc.title | In Vitro Antioxidant Activity and Total Phenolic Content of Root Extracts from Phragmanthera glaucocarpa (Peyr.) Balle | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F00709%2F2013/PT | |
| oaire.citation.conferencePlace | Irão | pt_PT |
| oaire.citation.startPage | e62238 | pt_PT |
| oaire.citation.title | Jundishapur journal of natural pharmaceutical products | pt_PT |
| oaire.citation.volume | 13 | pt_PT |
| oaire.fundingStream | 5876 | |
| person.familyName | Mendonca | |
| person.familyName | Mendonça | |
| person.givenName | Dina | |
| person.givenName | António | |
| person.identifier.ciencia-id | 5D12-6978-D7B5 | |
| person.identifier.ciencia-id | B112-0768-4411 | |
| person.identifier.ciencia-id | 2419-6E20-F958 | |
| person.identifier.orcid | 0000-0001-8747-7642 | |
| person.identifier.orcid | 0000-0001-9511-2942 | |
| person.identifier.orcid | 0000-0001-8069-0440 | |
| person.identifier.rid | AFO-4571-2022 | |
| person.identifier.rid | I-3093-2012 | |
| person.identifier.scopus-author-id | 6506834578 | |
| person.identifier.scopus-author-id | 56890866600 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.embargofct | Copyright cedido à editora no momento da publicação | pt_PT |
| rcaap.rights | closedAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 380b78e8-b5b2-4685-8e6f-0226966564b6 | |
| relation.isAuthorOfPublication | c5ae631b-1ee7-4d88-af70-eda0a565f4b7 | |
| relation.isAuthorOfPublication | fbccceb8-2850-4fe1-ae4f-4aeded7bf32a | |
| relation.isAuthorOfPublication.latestForDiscovery | fbccceb8-2850-4fe1-ae4f-4aeded7bf32a | |
| relation.isProjectOfPublication | cb4688cf-40da-4197-9eb0-c55bad699ad3 | |
| relation.isProjectOfPublication.latestForDiscovery | cb4688cf-40da-4197-9eb0-c55bad699ad3 |