ICI - Instituto Coordenador da Investigação
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O ICI integra Unidades de Investigação que exerçam as suas atividades na UBI e que tenham sido classificados com notação igual ou superior a Bom pelos painéis internacionais de avaliação periódica designados pela Fundação para a Ciência e Tecnologia.
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Browsing ICI - Instituto Coordenador da Investigação by Author "Abdullah, Baharudin"
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- Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)Publication . Bousquet, Jean; Schünemann, Holger; Sousa-Pinto, Bernardo; Zuberbier, Torsten; Togias, Alkis; Samoliński, Bolesław; Bedbrook, Anna; Czarlewski, Wienczyslawa; Hofmann-Apitius, Martin; Litynska, Justyna; Vieira, Rafael José; Giuliano, Antonio F.M.; Gotua, Maia; Gradauskiene, Brigita; Guzman, Maria Antonieta; Hossny, Elham; Hrubiško, Martin; Iinuma, Tomohisa; Irani, Carla; Ispayeva, Zhanat; Ivancevich, Juan Carlos; Anto, Josep M.; Jartti, Tuomas; Jesenak, Milos; Julge, Kaja; Jutel, Marek; Kaidashev, Igor; Bennoor, Kazi Saifuddin; Khaltaev, Nicolai; Kirenga, Bruce; Kraxner, Helga; Kull, Inger; Fonseca, Joao A; Kulus, Marek; Kuna, Piotr; Kupczyk, Maciej; Kurchenko, Andriy; La Grutta, Stefania; Lane, Stephen; Miculinic, Neven; Lee, Sang Min; Le Thi Tuyet, Lan; Lkhagvaa, Battur; Brozek, Jan; Louis, Renaud; Mahboub, Bassam; Mäkelä, Mika J.; Makris, Michael; Maurer, Marcus; Melén, Eric; Milenkovic, Branislava; Mohammad, Yousser; Moniuszko, Marcin; Montefort, Stephen; Bognanni, Antonio; Moreira, Andre; Moreno, Pablo; Mullol, Joaquim; Nadif, Rachel; Nakonechna, Alla; Navarro-Locsin, Cecilia Gretchen; Neffen, Hugo; Nekam, Kristof; Niedoszytko, Marek; Nunes, Elizabete; Brussino, Luisa; Nyembue Tshipukane, Dieudonne; O’Hehir, Robyn; Ollert, Markus; Ohta, Ken; Okamoto, Yoshitaka; Okubo, Kimihiro; Olze, Heidi; Padukudru, Mahesh Anand; Palomares, Oscar; Pali-Schöll, Isabella; Canonica, Giorgio Walter; Panzner, Petr; Palosuo, Kati; Park, Hae-Sim; Passalacqua, Giovanni; Patella, Vincenzo; Pawankar, Ruby; Pétré, Benoît; Pitsios, Constantinos; Plavec, Davor; Popov, Todor A.; Cherrez Ojeda, Ivan; Puggioni, Francesca; Quirce, Santiago; Raciborski, Filip; Ramonaité, Agné; Recto, Marysia; Repka- Ramirez, María Susana; Roberts, Graham; Robles-Velasco, Karla; Roche, Nicolas; Rodriguez-Gonzalez, Monica; Cruz, Alvaro; Romualdez, Joel A.; Rottem, Menachem; Rouadi, Philip; Salapatas, Marianella; Sastre, Joaquin; Serpa, Faradiba; Sayah, Zineb; Scichilone, Nicola; Senna, Gianenrico; Sisul, Juan; Vecillas, Leticia De Las; Solé, Dirceu; Soto-Martinez, Manuel E.; Sova, Milan; Sozinova, Olga; Stevanovic, Katarina; Suppli Ulrik, Charlotte; Szylling, Anna; Tan, Frances M.; Tantilipikorn, Pongsakorn; Bom, Ana Todo; Dykewicz, Mark; Tomic Spiric, Vesna; Tsaryk, Vladyslav; Tsiligianni, Ioanna; Urrutia-Pereira, Marilyn; Valentin Rostan, Marylin; Sofiev, Mikhail; Valovirta, Erkka; Van Eerd, Michiel; Van Ganse, Eric; Vasankari, Tuula; Gemicioglu, Bilun; Vichyanond, Pakit; Viegi, Giovanni; Wallace, Dana; Wang, De Yun; Waserman, Susan; Wong, Gary; Worm, Margitta; Yusuf, Osman; Zaitoun, Fares; Zidarn, Mihaela; Giovannini, Mattia; Haahtela, Tari; Jacobs, Marc; Jacomelli, Cristina; Klimek, Ludger; Kvedarienė, Violeta; Linnemann, Désirée Larenas; Louis, Gilles; Lourenço, Olga; Leemann, Lucas; Almeida, Mario Morais; Neves, Ana Luisa; Nadeau, Kari; Nowak, Artur; Palamarchuk, Yuliia; Palkonen, Susanna; Papadopoulos, Nikolaos G.; Parmelli, Elena; Pereira, Ana Margarida; Pfaar, Oliver; Regateiro, Frederico S.; Savouré, Marine; Barata, Luís Taborda; Toppila-Salmi, Sanna Katriina; Torres, María Jose; Valiulis, Arunas; Ventura, Maria Teresa; Williams, Siân; Yepes-Nuñez, Juan J.; Yorgancıoglu, Arzu; Zhang, Luo; Zuberbier, Jaron; Abdul Latiff, Amir; Abdullah, Baharudin; Agache, Ioana; Al-Ahmad, Mona; Al-Nesf, Maryam A Y; Al Shaikh, A.; Amaral, Rita; Ansotegui Zubeldia, Ignacio Javier; Asllani, Julijana; Balotro-Torres, Maria Cristina; Bergmann, Karl-Christian; Bernstein, Jonathan; Bindslev-Jensen, Carsten; Blaiss, Michael S.; Bonaglia, Cristina; Bonini, Matteo; Bossé, Isabelle; Braido, Fulvio; Caballero-Fonseca, Fernan; Camargos, Paulo; Martins, Pedro Carreiro; Casale, Thomas; Castillo-Vizuete, José-Antonio; Cecchi, Lorenzo; Teixeira, Maria Do Céu; Chang, Yoon-Seok; Loureiro, Cláudia Chaves; Christoff, George; Ciprandi, Giorgio; Cirule, Ieva; Sousa, Jaime Correia De; Costa, Elísio; Cvetkovski, Biljana; De Vries, Govert; Del Giacco, Stefano; Devillier, Philippe; Dokic, Dejan; Douagui, Habib; Durham, Stephen; Enecilla, Maria Lourdes; Fiocchi, Alessandro; Fokkens, Wytske; Fontaine, Jean-François; Gawlik, Radoslaw; Gereda, Jose E.; Mata, Sara GilAbstract The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure that people's values and preferences guide clinical decisions. This paper reviews current knowledge to develop (1) digital care pathways for rhinitis and asthma multimorbidity and (2) digitally enabled, person-centered care.1 It combines all relevant research evidence, including the so-called real-world evidence, with the ultimate goal to develop digitally enabled, patient-centered care. The paper includes (1) Allergic Rhinitis and its Impact on Asthma (ARIA), a 2-decade journey, (2) Grading of Recommendations, Assessment, Development and Evaluation (GRADE), the evidence-based model of guidelines in airway diseases, (3) mHealth impact on airway diseases, (4) From guidelines to digital care pathways, (5) Embedding Planetary Health, (6) Novel classification of rhinitis and asthma, (7) Embedding real-life data with population-based studies, (8) The ARIA-EAACI (European Academy of Allergy and Clinical Immunology) strategy for the management of airway diseases using digital biomarkers, (9) Artificial intelligence, (10) The development of digitally enabled, ARIA person-centered care, and (11) The political agenda. The ultimate goal is to propose ARIA 2024 guidelines centered around the patient to make them more applicable and sustainable.
- Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL hypothesisPublication . Bousquet, Jean; Melén, Erik; Haahtela, Tari; Koppelman, Gerard; Togias, Alkis; Valenta, Rudolf; Akdis, Cezmi; Czarlewski, Wienczyslawa; Rothenberg, Marc; Valiulis, Arunas; Wickman, Magnus; Aberer, Werner; Heinrich, Joachim; Sisul, Juan; Nunes, Elizabete; Plavec, Davor; Agache, Ioana; Al-Ahmad, Mona; Serpa, Faradiba; Alobid, Isam; Kalayci, Omer; Vichyanond, Pakit; Giacco, S. Del; Fiocchi, Alessandro; Ansotegui Zubeldia, Ignacio Javier; Custovic, Adnan; Martins, Pedro Carreiro; Rouadi, Philip; Arshad, Syed Hasan; Asayag, Estrella; Bárbara, Cristina; Abdullah, Baharudin; Moniuszko, Marcin; Tomazic, Peter Valentin; Popov, T. A.; Sayah, Zineb; Lkhagvaa, Battur; Nyembue Tshipukane , Dieudonne; Thomas, Mike; Bennoor, Kazi Saifuddin; Fyhrquist, Nanna Theresia; Irani, Carla; Berghea, Elena Camelia; Ėmužytė, Regina; De Blay, Frédéric; Toppila-Salmi, Sanna Katriina; Bergmann, Karl-Christian; Bernstein, D.; Bewick, M.; Casale, Thomas; Scheire, Sophie; Bumbacea, Roxana Silvia; Cepeda Sarabia, Alfonso; Puggioni, Francesca; Bush, Andrew; Chandrasekharan, Ramanathan; Ohta, Ken; Okubo, Kimihiro; Charpin, Denis; Gomez, R Maximiliano; Chen, Y. Z.; O'Hehir, Robyn; Cherrez Ojeda, Ivan; Bedbrook, Anna; To, Teresa; Chu, Derek K; Devillier, Philippe; Schmid-Grendelmeier, Peter; Didier, Alain; Repka-Ramirez, María Susana; Teixeira, Maria Do Céu; Ispayeva, Zhanat; Dokic, Dejan; Quirce, Santiago; Douagui , Habib; Ivancevich, Juan Carlos; Viegi, Giovanni; Gotua, Maia; Todo-Bom, Ana; Blain, Hubert; Guzman, Maria Antonieta; Kalyoncu, Ali Fuat; Hagemann, Jan; Buhl, Roland; Hamamah, Samir; Caraballo, Luis; Jares, Edgardo; Wallace, Dana; Chivato, Tomás; Jartti, Tuomas; Jassem, Ewa; Christoff, George; Julge, Kalev; Ogulur, Ismail; Kardas, Przemyslaw; Doulaptsi, Maria; Kirenga, Bruce; Helga, Kraxner; Durham, Stephen; Kull, Inger; Kulus, Marek; Daniel, Aguilar; Shamji, Mohamed; Kuna, Piotr; Nadif, Rachel; La Grutta, Stefania; Brightling, Chris; Samoliński, Bolesław; Lau, Susanne; Wang, De Yun; Cordeiro, Carlos Manuel Da Silva Robalo; Solé, Dirceu; Le Thi Tuyet, Lan; Recto, Marysia; Ouedraogo, Solange; Halken, Susanne; Levin, Michael; Lipworth, Brian; Lourenço, Olga; Mahboub, Bassam; Vandenplas, O.; Niedoszytko, Marek; Sastre, Joaquin; Martinez‐Infante, E.; Kupczyk, Maciej; Torres, María Jose; Matricardi, Paolo Maria; Cecchi, Lorenzo; Celedón, Juan C; Miculinic, Neven; Roche, Nicolas; Just, Jocelyne; Migueres, Nicolas; Brussino, Luisa; Florin, Mihaltan; Olze, Heidi; Savouré, Marine; Nekam, Kristof; Pali, Isabella; Okamoto, Yoshitaka; Palomares, O.; Lemonnier, Nathanaël; Carlsen, Karin C. Lodrup; Palosuo, Kati; Soto-Martinez, Manuel; Panaitescu, Carmen; Kvedarienė, Violeta; Panzner, P.; Braido, Fulvio; Tsiligianni, Ioanna; Rodriguez-Gonzalez, Monica; Scichilone, Nicola; Canonica, Giogio Walter; Passalacqua, Giovanni; Romantowski, Jan; Urrutia-Pereira, Marilyn; Filho, Nelson Augusto Rosario; Ollert, Markus W.; Rottem, Menachem; Chkhartishvili, Ekaterine; Sova, Milan; Valovirta, Erkka; Mohammad, Yousser; Sperl, Annette; Williams, Siân; Spranger, Otto; Neffen, Hugo; Stelmach, Rafael; Burte, Emilie; Valentin Rostan, Marylin; Park, Hae-Sim; Van Ganse, Eric; Van Hage, Marianne; Pitsios, Constantinos; Vasankari, Tuula; Linnemann, Désirée Larenas; Loureiro, Cláudia Chaves; Sagara, Hironori; Worm, Margitta; Yiallouros, Panayiotis; Yusuf, Osman; Zaitoun, Fares; Bonini, Matteo; Hrubiško, Martin; Cingi, C.; Dykewicz, Mark; Zernotti, Mario; Calderon, Moises; Halpin, David M.G.; Zidarn, Mihaela; Patella, Vincenzo; Sheikh, Aziz; Zuberbier, Jaron; Papadopoulos, Nikolaos; Louis, Renaud; Suppli Ulrik, Charlotte; Fonseca, João P.; Zuberbier, Torsten; Anto, Josep M.; Costa, Elisio; Eiwegger, Thomas; Bosnic-Anticevich, Sinthia; Cruz, Alvaro; Sousa, Jaime Correia de; Louis-Philippe, Boulet; Erhola, Marina; Cardona, Victoria; Carr, Warner; Gemicioglu, Bilun; Pawankar, Ruby; Fokkens, Wytske; Calvo, Mário; Garcia-Aymerich, J.; Mäkelä, Mika J.; Hofmann, Maja Ann; Klimek, Ludger; Makris, Michael; Mohamed Sayed, Zeinab; Maurer, Marcus; D'Amato, G.; Momas, Isabelle; Siroux, Valérie; Almeida, Mário Morais; Corrigan, Chris; Mullol, Joaquim; Montefort, Stephen; Jutel, Marek; Pham Thi, Nhan; Hossny, Elham; Akdis, Mubeccel; Pfaar, Oliver; Ventura, Maria Teresa; Regateiro, Frederico S.; Bindslev-Jensen, Carsten; Ring, Johannes; Bustamante, Mariona; Pinto, Bernardo Sousa; Kaidashev, Igor; Guerra, Stefano; Standl, Marie; Sunyer, J.; Keil, Thomas; Barata, Luís Taborda; Camargos, Paulo; Weiss, Scott; Naclerio, Robert; Yorgancıoglu, Arzu; Zhang, Luo; Nadeau, Kari; Abdul Latiff, AmirAsthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis.