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Percorrer por autor "Bewick, Michael"

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  • ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice
    Publication . Bousquet, Jean; Anto, Josep M.; Bachert, Claus; Haahtela, Tari; Zuberbier, Torsten; Czarlewski, Wienczyslawa; Bedbrook, Anna; Bosnic-Anticevich, Sinthia; Canonica, Giorgio Walter; Cardona, Victoria; Costa, Elísio; Farrell, John; Wroczynski, Piotr; Bjermer, Leif; Mair, Alpana; Lieberman, Philip; Odemyr, Mikaëla; Agache, Ioana; Larenas Linnemann, Désirée; Ventura, Maria Teresa; Makris, Michael; Samolinski, Boleslaw; Sofiev, Mikhail; Kvedarienė, Violeta; Carreiro-Martins, Pedro; Rolland, Christine; Usmani, Omar; Popov, Todor A; Williams, Dennis M; Sova, Milan; Manning, Patrick; Sheikh, Aziz; Pépin, Jean-Louis; Wagenmann, Martin; Mahboub, Bassam; Milenkovic, Branislava; Louis, Renaud; Laune, Daniel; Zidarn, Mihaela; Okamoto, Yoshitaka; Bonniaud, Philippe; Sisul, Juan; Ansotegui, Ignacio J; Stelmach, Rafael; Bennoor, Kazi Saifuddin; La Grutta, Stefania; O'Hehir, Robyn; De Manuel Keenoy, Esteban; Kleine-Tebbe, Joerg; Nyembue, Dieudonné; Passalacqua, Giovanni; Mitsias, Dimitirios I; Cecchi, Lorenzo; Novellino, Ettore; Buhl, Roland; Pinnock, Hilary; Klimek, Ludger; Ljungberg, Henrik; Akdis, Cezmi A; Gaga, Mina; Custovic, Adnan; Nordlund, Björn; Camargos, Paulo; Billo, Nils E.; Costa, David J; Briedis, Vitalis; Mogica-Martinez, Maria-Dolores; Panzner, Peter; Bourret, Rodolphe; Pham-Thi, Nhân; Schünemann, Holger J; Yorgancioglu, Arzu; Orlando, Valentina; Braido, Fulvio; Okubo, Kimihiro; To, Teresa; Ohta, Ken; Bindslev-Jensen, Carsten; D Bateman, Eric; Durham, Stephen R; Erhola, Marina; Yiallouros, Panayiotis; Cepeda Sarabia, Alfonso M; Lourenço, Olga; Cvetkosvki, Biljana; Napoli, Luigi; Roche, Nicolas; Salimäki, Johanna; Plavec, Davor; Morais-Almeida, Mario; Roberts, Graham; Scheire, Sophie; Camuzat, Thierry; Kull, Inger; Joos, Guy; Rivero-Yeverino, Daniela; Gomez, R Maximiliano; Somekh, David; Iinuma, Tomohisa; Portejoie, Fabienne; Neffen, Hugo; Cartier, Christine; Khaltaev, Nikolai; Rolland, Christine; Reitsma, Sietze; Dykewicz, Mark; Guldemond, Nick A; De Vries, Govert; Gevaert, Philippe; Rosario, Nelson; Fiocchi, Alessandro; De Feo, Giulia; Sastre, Joaquin; Emuzyte, Regina; Bosse, Isabelle; Zhang, Luo; Carriazo, Ana-Maria; Bewick, Michael; Rottem, Menachem; Fauquert, Jean-Luc; Calderon, Moises A; Roller-Wirnsberger, Regina E; Mullol, Joaquim; Rodriguez-Zagal, Erendira; Devillier, Philippe; Sousa, Jaime Correia de; Ebisawa, Motohiro; Kowalski, Marek L; Bedolla-Barajas, Martin; Huerta Villalobos, Yunuen R; Jung, Ki-Suck; Raciborski, Filip; Vezzani, Giorgio; Schmid-Grendelmeier, Peter; Psarros, Fotis; Carneiro, Antonio Vaz; Wong, Gary; Sooronbaev, Talant; Makela, Mika; Vasankari, Tuula; Zeng, Stéphane; Dokic, Dejan; Regateiro, Frederico S; Guzman, Maria Antonieta; Naclerio, Robert; Micheli, Yann; Vandenplas, Olivier; Malva, João; Illario, Maddalena; Menditto, Enrica; Spertini, François; Wickman, Magnus; Leonardini, Lisa; Heffler, Enrico; Basagaña, Xavier; Gotua, Maia; Wallace, Dana; Ivancevich, Juan-Carlos; Viart, Frédéric; Bonini, Matteo; Khaitov, Musa; Ierodiakonou, Despo; Münter, Lars; Courbis, Anne-Lise; Casale, Thomas; Mathieu-Dupas, Eve; Di Capua, Stefania; Miculinic, Neven; Valenta, Rudolf; Toppila-Salmi, Sanna Katriina; Zernotti, Mario E; Thibaudon, Michel; Tomazic, Peter Valentin; Annesi-Maesano, Isabella; Jutel, Marek; Quinones-Delgado, Pablo; Phillips, Jim; Todo-Bom, Ana; Onorato, Gabrielle L.; Benveniste, Samuel; Shan Zhong, Nan; Pereira, Marilyn Urrutia; Maspero, Jorge F; Prokopakis, Emmanuel P; Valiulis, Arunas; Suppli Ulrik, Charlotte; Muraro, Antonella; Palamarchuk, Julia; Mohammad, Yousser; Le Thi Tuyet, Lan; Neou, Angelo; Kuna, Piotr; Almeida, Rute; Namazova-Baranova, Leyla; Kritikos, Vicky; Chu, Derek K; Marshall, Gailen D; Kardas, Przemyslaw; Williams, Sian; Nekam, Kristof; Valovirta, Erkka; Dubakiene, Ruta; Tsiligianni, Ioanna; Montefort, Steve; Meltzer, Eli O; Murray, Ruth; Pugin, Benoit; Jassem, Ewa; Park, Hae-Sim; Picard, Robert; Brusselle, Guy; Arnavielhe, Sylvie; Patella, Vincenzo; Brozek, Jan; Carr, Warner; Bergmann, Karl-Christian; Melén, Erik; Brightling, Christopher E; H Chavannes, Niels; Moda, Giuliana; Pali-Schöll, Isabella; Valero, Antonio; Sofiev, Mikhail; Briggs, Andrew; Romano, Antonino; D'Amato, Gennaro; Shamji, Mohamed; Bialek, Slawomir; Caraballo, Luis; Rajabian-Söderlund, Rojin; Iaccarino, Guido; Ouedraogo, Solange; Buonaiuto, Roland; Silva, J da; Brussino, Luisa; Kouznetsov, Rostislav; Price, David; Paulino, Ema; Toumi, Mondher; Mercier, Jacques; Scadding, Glenis K; Monti, Ricardo; Solé, Dirceu; Boulet, Louis-Philippe; Gemicioglu, Bilun; Chkhartishvili, Ekaterine; Blain, Hubert; Fuentes Perez, José M; Humbert, Marc; Dantas, Carina; Yusuf, Osman; Fontaine, Jean-François; Viegi, Giovanni; Kaidashev, Igor; Cingi, Cemal; Boussery, Koen; Sanchez-Borges, Mario; Papadopoulos, Nikos G; Fokkens, Wytske J; Fink-Wagner, Antje; Wang, De Yun; Spranger, Otto; Cruz, Alvaro; Van Eerd, Michiel; Dauvilliers, Yves; Hajjam, Jawad; Valentin Rostan, Marylin; Puggioni, Francesca; Melo-Gomes, Elisabete; Ryan, Dermot; González Diaz, Sandra; Van Der Kleij, Rianne; Garcia-Aymerich, Judith; Mösges, Ralph; Gamkrelidze, Amiran; Stellato, Cristiana; Sarquis Serpa, Faradiba; Niedoszytko, Marek; Pfaar, Oliver; Pawankar, Ruby; Zar, Heather J; Loureiro, Claudia C; Fonseca, Joao A; El-Gamal, Yehia; Lopes-Pereira, Catarina; Masjedi, Mohamed R; Kalayci, Omer; Dray, Gerard; Carlsen, Karin C. Lodrup; Maurer, Marcus; Waserman, Susan; Bouchard, Jacques; Becker, Sven; Lipworth, Brian; Walker, Samantha; Mihaltan, Florin; Bédard, Annabelle; Keil, Thomas
    Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.
    2021Artigo científico Acesso aberto Ver mais
  • Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: The ARIA‐MASK‐air® approach
    Publication . Bousquet, Jean; Anto, Josep M.; Sousa-Pinto, Bernardo; Czarlewski, Wienczyslawa; Bedbrook, Anna; Haahtela, Tari; Klimek, Ludger; Pfaar, Oliver; Kuna, Piotr; Kupczyk, Maciej; Regateiro, Frederico S.; Palamarchuk, Yuliia; Pépin, Jean‐Louis; Pétré, Benoit; Picard, Robert; Pitsios, Constantinos; Puggioni, Francesca; Quirce, Santiago; Raciborski, Filip; Reitsma, Sietze; Roche, Nicolas; Samolinski, Boleslaw; Rodriguez‐Gonzalez, Monica; Romantowski, Jan; Sousa, Ana Sá; Serpa, Faradiba S.; Savouré, Marine; Shamji, Mohamed H.; Sova, Milan; Sperl, Annette; Stellato, Cristiana; Todo‐Bom, Ana; Valiulis, Arunas; Tomazic, Peter Valentin; Vandenplas, Olivier; Van Eerd, Michiel; Vasankari, Tuula; Viart, Frédéric; Waserman, Susan; Fonseca, Joao A; Zuberbier, Torsten; Yorgancioglu, Arzu; Arnavielhe, Sylvie; Basagaña, Xavier; Bergmann, Karl C.; Bosnic‐Anticevich, Sinthia; Brussino, Luisa; Canonica, Giorgio Walter; Cardona, Victoria; Cecchi, Lorenzo; Loureiro, Cláudia Chaves; Costa, Elísio; Cruz, Alvaro A.; Gemicioglu, Bilun; Fokkens, Wytske; Ivancevich, Juan Carlos; Kraxner, Helga; Kvedariene, Violeta; Linnemann, Désirée E. Larenas; Laune, Daniel; Louis, Renaud; Makris, Michael; Maurer, Marcus; Melén, Erik; Micheli, Yann; Almeida, Mário Morais; Mullol, Joaquim; Niedoszytko, Marek; Okamoto, Yoshitaka; Papadopoulos, Nikolaos G.; Patella, Vincenzo; Pham‐Thi, Nhân; Rouadi, Philip W.; Sastre, Joaquin; Scichilone, Nicola; Sheikh, Aziz; Sofiev, Mikhail; Barata, Luís Taborda; Salmi, Sanna Toppila; Tsiligianni, Ioanna; Valovirta, Erkka; Ventura, Maria Teresa; Vieira, Rafael José; Zidarn, Mihaela; Amaral, Rita; Ansotegui, Ignacio J.; Bédard, Annabelle; Benveniste, Samuel; Bewick, Michael; Jensen, Carsten Bindslev; Blain, Hubert; Bonini, Matteo; Bourret, Rodolphe; Braido, Fulvio; Martins, Pedro Carreiro; Charpin, Denis; Cherrez‐Ojeda, Ivan; Chivato, Tomas; Chu, Derek K.; Cingi, Cemal; Del Giacco, Stefano; de Blay, Frédéric; Devillier, Philippe; De Vries, Govert; Doulaptsi, Maria; Doyen, Virginie; Dray, Gérard; Fontaine, Jean‐François; Gomez, R. Maximiliano; Hagemann, Jan; Heffler, Enrico; Hofmann, Maja; Jassem, Ewa; Jutel, Marek; Keil, Thomas; Kritikos, Vicky; Kull, Inger; Kulus, Marek; Lourenço, Olga; Mathieu‐Dupas, Eve; Menditto, Enrica; Mösges, Ralph; Murray, Ruth; Nadif, Rachel; Neffen, Hugo; Nicola, Stefania; O’Hehir, Robyn; Olze, Heidi
    MASK‐air®, a validated mHealth app (Medical Device regulationClass IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK‐air® is a Good Practice of DG Santé on digitally‐enabled, patient‐centred care. Itis also a candidate Good Practice ofOECD (Organisation for EconomicCo‐operation and Development). MASK‐air® data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK‐air® data show that most rhinitis patients (i) are not adherent and do notfollow guidelines, (ii) use as‐needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recom mended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom‐medication score (ARIA‐EAACI‐CSMS) has been validated for clinical practice and trials. The implications of the novel MASK‐air® results should lead to change management in rhinitis and asthma.
    2023Artigo científico Acesso aberto Ver mais
  • Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases
    Publication . Bousquet, Jean; Schünemann, Holger; Togias, Alkis; Erhola, Marina; Hellings, Peter; Zuberbier, Torsten; Agache, Ioana; Ansotegui Zubeldia, Ignacio Javier; Anto, Josep M.; Bachert, Claus; Becker, Sven; Kvedarienė, Violeta; Yusuf, Osman; Ohta, Ken; Moda, Giuliana; Münter, Lars; Chu, Derek K; Lourenço, Olga; Ryan, Dermot; Kuna, Piotr; Devillier, Philippe; Novellino, Enrico; Bergmann, Karl-Christian; Bonini, Mateo; Billo, Nils; Mathieu-Dupas, Eve; Portejoie, Fabienne; Reitsma, Sietze; Farrell, John; Sheikh, Aziz; Haahtela, Tari; Dykewickz, Marc; Morais-Almeida, Mario; Namazova-Baranova, Leyla; Cvetkosvki, Biljana; Fiocchi, Alessandro; Stelmach, Rafael; Samoliński, Bolesław; Brightling, Christofer E; Cardona, Victoria; Buhl, Roland; Miculinic, Neven; Salimäki, Johanna; Ebisawa, Motohiro; Iaccarino, Guido; Bedolla-Barajas, Martin; Roche, Nicolas; Guldemond, Nick A; Dauvilliers, Yves; Palkonen, Susanna; Fonseca, Joao A; Basagaña, Xavier; Cartier, Christine; Chkhartishvili, Ekaterine; Cecchi, Lorenzo; Monti, Ricardo; Suppli Ulrik, Charlotte; Kleine-Tebbe, Jorg; Annesi-Maesano, Isabella; Kardas, Przemyslaw; Garcia-Aymerich, Judith; Pugin, Benoit; Picard, Robert; Fontaine, Jean F; Colgan, Elaine; Custovic, Adnan; Murray, Ruth; van der Kleij, Rianne; Bjermer, Leif; Lodrup Carlsen, Karin C; Jutel, Marek; Solé, Dirceu; Williams, Sian; Illario, Maddalena; Ouedraogo, Solange; Nekam, Kristof; Wang, De Y; Buonaiuto, Roland; Lieberman, Philip; Todo-Bom, Ana; Bindslev-Jensen, Carsten; Kritikos, Vicky; Price, David; Paulino, Ema; Cepeda Sarabia, Alfonso M; De Manuel Keenoy, Esteban; Viart, Frédéric; Okubo, Kimihiro; Sanchez-Borges, Mario; Dubakiene, Ruta; Courbis, Anne Lise; Bourrez, Jean Marc; Gaga, Mina; Thibaudon, Michel; Guzman, Maria Antonieta; Dantas, Carina; Menditto, Enrica; Pinnock, Hilary; Keil, Thomas; De Feo, Giulia; Gotua, Maia; Silva, J da; Laune, Daniel; Williams, Dennis M; Zeng, Stéphane; Montefort, Steve; Hajjam, Jawad; Bedbrook, Anna; González Diaz, Sandra; Neou, Angelo; Marien, Gert; Marshall, Gailen D; Malva, Joao; Vandenplas, Olivier; Valiulis, Arunas; Akdis, Cezmi A; Pali-Schöll, Isabella; Kalayci, Omer; Gamkrelidze, Amiran; Nyembue Tshipukane , Dieudonne; Zidarn, Mihaela; Muraro, Antonella; Costa, Elísio; Bonniaud, Philippe; Kaidashev, Igor; Matricardi, Poalo M; Menditto, Enrica; Melo-Gomes, Elisabete; Waserman, Susan; Bennoor, Kazi Saifuddin; Prokopakis, Emmanuel P; Di Capua, Stefania; Jung, Ki-Suck; Plavec, Davor; Neffen, Hugo; Papadopoulos, Nikos; Gemicioglu, Bilun; Lipworth, Brian; Mihaltan, Florin; Mohammad, Yousser; Yorgancıoglu, Arzu; Bouchard, Jacques; Sisul, Juan-Carlos; Leonardini, Lisa; Rottem, Menahenm; Pfaar, Oliver; Ventura, Maria Teresa; Ivancevich, Juan C; Panzner, Peter; Brusselle, Guy; Zhang, Luo; Carriazo, Ana M; Manning, Patrick; Stellato, Cristina; Romano, Antonino; Bialek, Slawomir; Kull, Inger; Raciborski, Filip; Mullol, Joaquin; Klimek, Ludger; Meltzer, Eli O; Spranger, Otto; Brozek, Jan; Boulet, Louis P; Somekh, David; Valovirta, Erkka; Rolland, Christine; Mogica Martinez, Maria Dolores; Valenta, Rudolf; Casale, Thomas; Benveniste, Samuel; O'Hehir, Robyn; Mösges, Ralf; Eller, Esben; Schmid-Grendelmeir, Peter; Briedis, Vitalis; Popov, Ted A; Napoli, Luigi; O'B Hourihane, John; Joos, Guy; Chavannes, Niels; Picard, Robert; Naclerio, Robert; Bewick, Michael; Sousa, Jaime Correia de; Dokic, Dejan; Yiallouros, Panayiotis; Cruz, Alvaro; Loureiro, Claudia C; Phillips, Jim; To, Teresa; Valentin Rostan, Marylin; Tomazic, Peter Valentin; Carr, Warner; Khaitov, Mussa; Bosse, Isabelle; Okamoto, Yoshitaka; Czarlewski, Wienczyslawa; Pereira, Ana-Maria; Le Thi Tuyet, Lan; Zernotti, Mario; Fink-Wagner, Antjie; Masjedi, Mohamed R; Rosario, Nelson; Vezzani, Giorgio; Wagenmann, Martin; Viegi, Giovanni; Cingi, Cemal; Louis, Renaud; Vasankari, Tuula; Rodo, Xavier; Toppila-Salmi, Sanna; Illario, Maddalena; Ierodiakonou, Despo; Park, Hae-Sim; Fokkens, Wytske J; Wickman, Magnus; Wroczynski, Piotr; D'Amato, Gennaro; Maspero, Jorge F; Sova, Milan; Bateman, Eric; Roller-Wirnsberger, Regina E; Kowalski, Marek L; Rajabian-Söderlund, Rojin; Pham-Thi, Nhân; Emuzyte, Regina; Dedeu, Antoni; Mercier, Jacques; Valero, Antonio; Arnavielhe, Sylvie; Mahboub, Bassam; Sooronbaev, Talant; Walker, Samantha; Humbert, Marc; Gomez, Maximiliano; Wallace, Dana; Blain, Hubert; Melén, Erik; El-Gamal, Yaya; Khaltaev, Nikolai; Bosnic-Anticevich, Sinthia; Wong, Gary; Canonica, Giorgo W; Milenkovic, Branislava; Mair, Alpana; Linnemann, Désirée Larenas; Zar, Heather J; Onorato, Gabrielle; Pépin, Jean-Louis; Tsiligianni, Ioanna; Zhong, Nan S
    Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted “patient activation”, (ii) Implementation of care pathways by pharmacists and (iii) Nextgeneration guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.
    2019Artigo científico Acesso aberto Ver mais
  • Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA‐EAACI approach – ARIA‐EAACI Task Force Report
    Publication . Bousquet, Jean; Shamji, Mohamed; Anto, Josep M.; Schünemann, Holger; Canonica, Giorgio Walter; Jutel, Marek; Del Giacco, Stafano; Zuberbier, Torsten; Pfaar, Oliver; Fonseca, Joao A; Pinto, Bernardo Sousa; Pétré, Benoit; Pham‐Thi, Nhân; Puggioni, Francesca; Quirce, Santiago; Roche, Nicolas; Rouadi, Philip; Sousa, Ana Sá; Sagara, Hironori; Sastre, Joaquin; Scichilone, Nicola; Sheikh, Aziz; Sova, Milan; Ulrik, Charlotte Suppli; Taborda Barata, Luis; Todo-Bom, Ana; Torres, María Jose; Tsiligianni, Ioanna; Usmani, Omar; Valovirta, Erkka; Vasankari, Tuula; Vieira, Rafael José; Wallace, Dana; Waserman, Susan; Zidarn, Mihaela; Yorgancıoglu, Arzu; Zhang, Luo; Chivato, Tomás; Ollert, Markus; Klimek, Ludger; Czarlewski, Wienczyslawa; Bedbrook, Anna; Amaral, Rita; Ansotegui Zubeldia, Ignacio Javier; Bosnic-Anticevich, Sinthia; Braido, Fulvio; Loureiro, Cláudia Chaves; Gemicioglu, Bilun; Haahtela, Tari; Kulus, Marek; Kuna, Piotr; Kupczyk, Maciej; Matricardi, Paolo Maria; Regateiro, Frederico S.; Samoliński, Bolesław; Sofiev, Mikhail; Toppila-Salmi, Sanna; Valiulis, Arunas; Ventura, Maria Teresa; Bárbara, Cristina; Bergmann, Karl-Christian; Bewick, Michael; Blain, Hubert; Bonini, Matteo; Boulet, Louis-Philippe; Bourret, Rodolphe; Brusselle, Guy; Brussino, Luisa; Buhl, Roland; Cardona, Victoria; Casale, Thomas; Cecchi, Lorenzo; Charpin, Denis; Cherrez Ojeda, Ivan; Chu, Derek K; Cing, Cemal; Costa, Elísio; Cruz, Álvaro A.; Devillier, Philippe; Dramburg, Stephanie; Fokkens, Wytske; Gotua, Maia; Heffler, Enrico; Ispayeva, Zhanat; Ivancevich, Juan Carlos; Joos, Guy; Kaidashev, Igor; Kraxner, Helga; Kvedarienė, Violeta; Larenas Linnemann, Désirée; Laune, Daniel; Lourenço, Olga; Louis, Renaud; Mäkelä, Mika J.; Makris, Michael; Maurer, Marcus; Melén, Erik; Micheli, Yann; Almeida, Mário Morais; Mullol, Joaquim; Niedoszytko, Marek; O'Hehir, Robyn; Okamoto, Yoshitaka; Olze, Heidi; Papadopoulos, Nikolaos G.; Papi, Alberto; Patella, Vincenzo
    Biomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/ or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the center of the health system and is likely to optimize the practice of allergy. Allergic Rhinitis and its Impact on Asthma (ARIA) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient-reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomized controlled trials, observational real-life studies and allergen challenges. Using the MASK-air app as a model, a daily electronic combined symptom-medication score for allergic diseases (CSMS) or for asthma (e-DASTHMA), combined with a monthly control questionnaire, was embedded in a strategy similar to the diabetes approach for disease control. To mimic real-life, it secondly proposed quality-of- life digital biomarkers including daily EQ-5D visual analogue scales and the bi-weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed.
    2023Artigo científico Acesso aberto Ver mais