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- ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practicePublication . Bousquet, Jean; Anto, Josep M.; Bachert, Claus; Haahtela, Tari; Zuberbier, Torsten; Czarlewski, Wienczyslawa; Bedbrook, Anna; Bosnic-Anticevich, Sinthia; Canonica, Giorgio Walter; Cardona, Victoria; Costa, Elísio; Farrell, John; Wroczynski, Piotr; Bjermer, Leif; Mair, Alpana; Lieberman, Philip; Odemyr, Mikaëla; Agache, Ioana; Larenas Linnemann, Désirée; Ventura, Maria Teresa; Makris, Michael; Samolinski, Boleslaw; Sofiev, Mikhail; Kvedarienė, Violeta; Carreiro-Martins, Pedro; Rolland, Christine; Usmani, Omar; Popov, Todor A; Williams, Dennis M; Sova, Milan; Manning, Patrick; Sheikh, Aziz; Pépin, Jean-Louis; Wagenmann, Martin; Mahboub, Bassam; Milenkovic, Branislava; Louis, Renaud; Laune, Daniel; Zidarn, Mihaela; Okamoto, Yoshitaka; Bonniaud, Philippe; Sisul, Juan; Ansotegui, Ignacio J; Stelmach, Rafael; Bennoor, Kazi Saifuddin; La Grutta, Stefania; O'Hehir, Robyn; De Manuel Keenoy, Esteban; Kleine-Tebbe, Joerg; Nyembue, Dieudonné; Passalacqua, Giovanni; Mitsias, Dimitirios I; Cecchi, Lorenzo; Novellino, Ettore; Buhl, Roland; Pinnock, Hilary; Klimek, Ludger; Ljungberg, Henrik; Akdis, Cezmi A; Gaga, Mina; Custovic, Adnan; Nordlund, Björn; Camargos, Paulo; Billo, Nils E.; Costa, David J; Briedis, Vitalis; Mogica-Martinez, Maria-Dolores; Panzner, Peter; Bourret, Rodolphe; Pham-Thi, Nhân; Schünemann, Holger J; Yorgancioglu, Arzu; Orlando, Valentina; Braido, Fulvio; Okubo, Kimihiro; To, Teresa; Ohta, Ken; Bindslev-Jensen, Carsten; D Bateman, Eric; Durham, Stephen R; Erhola, Marina; Yiallouros, Panayiotis; Cepeda Sarabia, Alfonso M; Lourenço, Olga; Cvetkosvki, Biljana; Napoli, Luigi; Roche, Nicolas; Salimäki, Johanna; Plavec, Davor; Morais-Almeida, Mario; Roberts, Graham; Scheire, Sophie; Camuzat, Thierry; Kull, Inger; Joos, Guy; Rivero-Yeverino, Daniela; Gomez, R Maximiliano; Somekh, David; Iinuma, Tomohisa; Portejoie, Fabienne; Neffen, Hugo; Cartier, Christine; Khaltaev, Nikolai; Rolland, Christine; Reitsma, Sietze; Dykewicz, Mark; Guldemond, Nick A; De Vries, Govert; Gevaert, Philippe; Rosario, Nelson; Fiocchi, Alessandro; De Feo, Giulia; Sastre, Joaquin; Emuzyte, Regina; Bosse, Isabelle; Zhang, Luo; Carriazo, Ana-Maria; Bewick, Michael; Rottem, Menachem; Fauquert, Jean-Luc; Calderon, Moises A; Roller-Wirnsberger, Regina E; Mullol, Joaquim; Rodriguez-Zagal, Erendira; Devillier, Philippe; Sousa, Jaime Correia de; Ebisawa, Motohiro; Kowalski, Marek L; Bedolla-Barajas, Martin; Huerta Villalobos, Yunuen R; Jung, Ki-Suck; Raciborski, Filip; Vezzani, Giorgio; Schmid-Grendelmeier, Peter; Psarros, Fotis; Carneiro, Antonio Vaz; Wong, Gary; Sooronbaev, Talant; Makela, Mika; Vasankari, Tuula; Zeng, Stéphane; Dokic, Dejan; Regateiro, Frederico S; Guzman, Maria Antonieta; Naclerio, Robert; Micheli, Yann; Vandenplas, Olivier; Malva, João; Illario, Maddalena; Menditto, Enrica; Spertini, François; Wickman, Magnus; Leonardini, Lisa; Heffler, Enrico; Basagaña, Xavier; Gotua, Maia; Wallace, Dana; Ivancevich, Juan-Carlos; Viart, Frédéric; Bonini, Matteo; Khaitov, Musa; Ierodiakonou, Despo; Münter, Lars; Courbis, Anne-Lise; Casale, Thomas; Mathieu-Dupas, Eve; Di Capua, Stefania; Miculinic, Neven; Valenta, Rudolf; Toppila-Salmi, Sanna Katriina; Zernotti, Mario E; Thibaudon, Michel; Tomazic, Peter Valentin; Annesi-Maesano, Isabella; Jutel, Marek; Quinones-Delgado, Pablo; Phillips, Jim; Todo-Bom, Ana; Onorato, Gabrielle L.; Benveniste, Samuel; Shan Zhong, Nan; Pereira, Marilyn Urrutia; Maspero, Jorge F; Prokopakis, Emmanuel P; Valiulis, Arunas; Suppli Ulrik, Charlotte; Muraro, Antonella; Palamarchuk, Julia; Mohammad, Yousser; Le Thi Tuyet, Lan; Neou, Angelo; Kuna, Piotr; Almeida, Rute; Namazova-Baranova, Leyla; Kritikos, Vicky; Chu, Derek K; Marshall, Gailen D; Kardas, Przemyslaw; Williams, Sian; Nekam, Kristof; Valovirta, Erkka; Dubakiene, Ruta; Tsiligianni, Ioanna; Montefort, Steve; Meltzer, Eli O; Murray, Ruth; Pugin, Benoit; Jassem, Ewa; Park, Hae-Sim; Picard, Robert; Brusselle, Guy; Arnavielhe, Sylvie; Patella, Vincenzo; Brozek, Jan; Carr, Warner; Bergmann, Karl-Christian; Melén, Erik; Brightling, Christopher E; H Chavannes, Niels; Moda, Giuliana; Pali-Schöll, Isabella; Valero, Antonio; Sofiev, Mikhail; Briggs, Andrew; Romano, Antonino; D'Amato, Gennaro; Shamji, Mohamed; Bialek, Slawomir; Caraballo, Luis; Rajabian-Söderlund, Rojin; Iaccarino, Guido; Ouedraogo, Solange; Buonaiuto, Roland; Silva, J da; Brussino, Luisa; Kouznetsov, Rostislav; Price, David; Paulino, Ema; Toumi, Mondher; Mercier, Jacques; Scadding, Glenis K; Monti, Ricardo; Solé, Dirceu; Boulet, Louis-Philippe; Gemicioglu, Bilun; Chkhartishvili, Ekaterine; Blain, Hubert; Fuentes Perez, José M; Humbert, Marc; Dantas, Carina; Yusuf, Osman; Fontaine, Jean-François; Viegi, Giovanni; Kaidashev, Igor; Cingi, Cemal; Boussery, Koen; Sanchez-Borges, Mario; Papadopoulos, Nikos G; Fokkens, Wytske J; Fink-Wagner, Antje; Wang, De Yun; Spranger, Otto; Cruz, Alvaro; Van Eerd, Michiel; Dauvilliers, Yves; Hajjam, Jawad; Valentin Rostan, Marylin; Puggioni, Francesca; Melo-Gomes, Elisabete; Ryan, Dermot; González Diaz, Sandra; Van Der Kleij, Rianne; Garcia-Aymerich, Judith; Mösges, Ralph; Gamkrelidze, Amiran; Stellato, Cristiana; Sarquis Serpa, Faradiba; Niedoszytko, Marek; Pfaar, Oliver; Pawankar, Ruby; Zar, Heather J; Loureiro, Claudia C; Fonseca, Joao A; El-Gamal, Yehia; Lopes-Pereira, Catarina; Masjedi, Mohamed R; Kalayci, Omer; Dray, Gerard; Carlsen, Karin C. Lodrup; Maurer, Marcus; Waserman, Susan; Bouchard, Jacques; Becker, Sven; Lipworth, Brian; Walker, Samantha; Mihaltan, Florin; Bédard, Annabelle; Keil, ThomasDigital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.
- Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthmaPublication . Bousquet, Jean; Bedbrook, Anna; Czarlewski, W; Onorato, G L; Arnavielhe, S; Laune, Daniel; Mathieu-Dupas, Eve; Fonseca, J; Costa, E; Lourenço, Olga; Almeida, M Morais; Pham-Thi, N; Portejoie, F; Picard, Robert; Roche, N; Rolland, C; Schmidt-Grendelmeier, P; Kuna, P; Samolinski, Boleslaw; Anto, Josep M.; Cardona, V; Mullol, J; Pinnock, H; Ryan, D; Sheikh, A; Walker, S; Williams, S; Becker, S; Klimek, L; Pfaar, Oliver; Bergmann, Karl-Christian; Mösges, R; Zuberbier, T; Roller-Wirnsberger, R E; Tomazic, Peter Valentin; Haahtela, Tari; Salimäki, Johanna; Toppila-Salmi, S; Valovirta, Erkka; Vasankari, Tuula; Gemicioğlu, Bilun; Yorgancioglu, A; Papadopoulos, N; Prokopakis, E P; Tsiligianni, I G; Bosnic-Anticevich, S; O'Hehir, Robyn; Ivancevich, J C; Neffen, Hugo; Zernotti, M E; Kull, Inger; Melén, Erik; Wickman, M; Bachert, Claus; Hellings, Peter; Brusselle, G; Palkonen, S; Bindslev-Jensen, C; Eller, E; Waserman, S; Boulet, L P; Bouchard, J; Chu, D K; Schünemann, H J; Sova, M; De Vries, G; Van Eerd, Michiel; Agache, Ioana; Ansotegui, I J; Bewick, M; Casale, Thomas; Dykewick, M; Ebisawa, M; Murray, R; Naclerio, Robert; Okamoto, Yoshitaka; Wallace, D V; Todo-Bom, Ana; Illario, Maddalena; Menditto, E; Canonica, G W; Cecchi, Lorenzo; Monti, R; Napoli, Luigi; Ventura, Maria Teresa; De Feo, G; Fokkens, W J; Chavannes, N H; Reitsma, S; Cruz, A A; Silva, J da; Serpa, F S; Larenas Linnemann, Désirée; Fuentes Perez, J M; Huerta-Villalobos, Y R; Rivero-Yeverino, D; Rodriguez-Zagal, E; Valiulis, Arunas; Dubakiene, R; Emuzyte, R; Kvedarienė, Violeta; Annesi-Maesano, I; Blain, H; Bonniaud, P; Bosse, I; Dauvilliers, Y; Devillier, P; Fontaine, J F; Pépin, J LAims: Mobile Airways Sentinel NetworK (MASK) belongs to the Fondation Partenariale MACVIA-LR of Montpellier, France and aims to provide an active and healthy life to rhinitis sufferers and to those with asthma multimorbidity across the life cycle, whatever their gender or socio-economic status, in order to reduce health and social inequities incurred by the disease and to improve the digital transformation of health and care. The ultimate goal is to change the management strategy in chronic diseases. Methods: MASK implements ICT technologies for individualized and predictive medicine to develop novel care pathways by a multi-disciplinary group centred around the patients. Stakeholders: Include patients, health care professionals (pharmacists and physicians), authorities, patient’s associations, private and public sectors. Results: MASK is deployed in 23 countries and 17 languages. 26,000 users have registered.
- MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidencePublication . Bousquet, Jean; Arnavielhe, S; Bedbrook, Anna; Bewick, M; Laune, Daniel; Mathieu-Dupas, Eve; Murray, R; Onorato, G L; Pépin, J L; Picard, Robert; Portejoie, F; Costa, E; Fonseca, J; Lourenço, Olga; Almeida, M Morais; Todo-Bom, Ana; Cruz, A A; Silva, J da; Serpa, F S; Illario, Maddalena; Menditto, E; Cecchi, Lorenzo; Monti, R; Napoli, Luigi; Ventura, Maria Teresa; De Feo, G; Linnemann, Désirée Larenas; Fuentes Perez, M; Huerta Villabolos, Y R; Rivero-Yeverino, D; Rodriguez-Zagal, E; Amat, F; Annesi-Maesano, I; Bosse, I; Demoly, P; Devillier, P; Fontaine, J F; Just, Jocelyne; Kuna, T P; Samolinski, Boleslaw; Valiulis, Arunas; Emuzyte, R; Kvedarienė, Violeta; Ryan, D; Sheikh, A; Schmidt-Grendelmeier, P; Klimek, L; Pfaar, Oliver; Bergmann, Karl-Christian; Mösges, R; Zuberbier, T; Roller-Wirnsberger, R E; Tomazic, Peter Valentin; Fokkens, W J; Chavannes, N H; Reitsma, S; Anto, Josep M.; Cardona, V; Dedeu, T; Mullol, J; Haahtela, Tari; Salimäki, Johanna; Toppila-Salmi, S; Valovirta, Erkka; Gemicioglu, Bilun; Yorgancioglu, A; Papadopoulos, N; Prokopakis, E P; Bosnic-Anticevich, S; O'Hehir, Robyn; Ivancevich, J C; Neffen, Hugo; Zernotti, E; Kull, Inger; Melén, Erik; Wickman, M; Bachert, Claus; Hellings, Peter; Palkonen, S; Bindslev-Jensen, C; Eller, E; Waserman, S; Sova, M; De Vries, G; Van Eerd, Michiel; Agache, Ioana; Casale, Thomas; Dykewickz, M; Naclerio, Robert; Okamoto, Yoshitaka; Wallace, D VmHealth, such as apps running on consumer smart devices is becoming increasingly popular and has the potential to profoundly affect healthcare and health outcomes. However, it may be disruptive and results achieved are not always reaching the goals. Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline using the best evidence-based approach to care pathways suited to real-life using mobile technology in allergic rhinitis (AR) and asthma multimorbidity. Patients largely use over-the-counter medications dispensed in pharmacies. Shared decision making centered around the patient and based on self-management should be the norm. Mobile Airways Sentinel networK (MASK), the Phase 3 ARIA initiative, is based on the freely available MASK app (the Allergy Diary, Android and iOS platforms). MASK is available in 16 languages and deployed in 23 countries. The present paper provides an overview of the methods used in MASK and the key results obtained to date. These include a novel phenotypic characterization of the patients, confirmation of the impact of allergic rhinitis on work productivity and treatment patterns in real life. Most patients appear to self-medicate, are often non-adherent and do not follow guidelines. Moreover, the Allergy Diary is able to distinguish between AR medications. The potential usefulness of MASK will be further explored by POLLAR (Impact of Air Pollution on Asthma and Rhinitis), a new Horizon 2020 project using the Allergy Diary.
- Mobile Technology in Allergic Rhinitis: Evolution in Management or Revolution in Health and Care?Publication . Bousquet, Jean; Ansotegui, Ignacio J; Anto, Josep M.; Arnavielhe, Sylvie; Bachert, Claus; Basagaña, Xavier; Bédard, Annabelle; Bedbrook, Anna; Bonini, Matteo; Bosnic-Anticevich, Sinthia; Braido, Fulvio; Cardona, Vicky; Czarlewski, Wienczyslawa; Cruz, Alvaro A; Demoly, Pascal; De Vries, Govert; Dramburg, Stephanie; Mathieu-Dupas, Eve; Erhola, Marina; Fokkens, Wytske J; Fonseca, Joao A; Haahtela, Tari; Hellings, Peter; Illario, Maddalena; Ivancevich, Juan Carlos; Jormanainen, Vesa; Klimek, Ludger; Kuna, Piotr; Kvedarienė, Violeta; Laune, Daniel; Linnemann, Désirée Larenas; Lourenço, Olga; Onorato, Gabrielle L; Matricardi, Paolo M; Melén, Erik; Mullol, Joaquim; Papadopoulos, Nikos G; Pfaar, Oliver; Pham-Thi, Nhân; Sheikh, Aziz; Tan, Rachel; To, Teresa; Tomazic, Peter Valentin; Toppila-Salmi, Sanna; Tripodi, Salvadore; Wallace, Dana; Valiulis, Arunas; Van Eerd, Michiel; Ventura, Maria Teresa; Yorgancioglu, Arzu; Zuberbier, TorstenSmart devices and Internet-based applications (apps) are largely used in allergic rhinitis and may help to address some unmet needs. However, these new tools need to first of all be tested for privacy rules, acceptability, usability, and cost-effectiveness. Second, they should be evaluated in the frame of the digital transformation of health, their impact on health care delivery, and health outcomes. This review (1) summarizes some existing mobile health apps for allergic rhinitis and reviews those in which testing has been published, (2) discusses apps that include risk factors of allergic rhinitis, (3) examines the impact of mobile health apps in phenotype discovery, (4) provides real-world evidence for care pathways, and finally (5) discusses mobile health tools enabling the digital transformation of health and care, empowering citizens, and building a healthier society.
- Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseasesPublication . Bousquet, Jean; Schünemann, Holger; Togias, Alkis; Erhola, Marina; Hellings, Peter; Zuberbier, Torsten; Agache, Ioana; Ansotegui Zubeldia, Ignacio Javier; Anto, Josep M.; Bachert, Claus; Becker, Sven; Kvedarienė, Violeta; Yusuf, Osman; Ohta, Ken; Moda, Giuliana; Münter, Lars; Chu, Derek K; Lourenço, Olga; Ryan, Dermot; Kuna, Piotr; Devillier, Philippe; Novellino, Enrico; Bergmann, Karl-Christian; Bonini, Mateo; Billo, Nils; Mathieu-Dupas, Eve; Portejoie, Fabienne; Reitsma, Sietze; Farrell, John; Sheikh, Aziz; Haahtela, Tari; Dykewickz, Marc; Morais-Almeida, Mario; Namazova-Baranova, Leyla; Cvetkosvki, Biljana; Fiocchi, Alessandro; Stelmach, Rafael; Samoliński, Bolesław; Brightling, Christofer E; Cardona, Victoria; Buhl, Roland; Miculinic, Neven; Salimäki, Johanna; Ebisawa, Motohiro; Iaccarino, Guido; Bedolla-Barajas, Martin; Roche, Nicolas; Guldemond, Nick A; Dauvilliers, Yves; Palkonen, Susanna; Fonseca, Joao A; Basagaña, Xavier; Cartier, Christine; Chkhartishvili, Ekaterine; Cecchi, Lorenzo; Monti, Ricardo; Suppli Ulrik, Charlotte; Kleine-Tebbe, Jorg; Annesi-Maesano, Isabella; Kardas, Przemyslaw; Garcia-Aymerich, Judith; Pugin, Benoit; Picard, Robert; Fontaine, Jean F; Colgan, Elaine; Custovic, Adnan; Murray, Ruth; van der Kleij, Rianne; Bjermer, Leif; Lodrup Carlsen, Karin C; Jutel, Marek; Solé, Dirceu; Williams, Sian; Illario, Maddalena; Ouedraogo, Solange; Nekam, Kristof; Wang, De Y; Buonaiuto, Roland; Lieberman, Philip; Todo-Bom, Ana; Bindslev-Jensen, Carsten; Kritikos, Vicky; Price, David; Paulino, Ema; Cepeda Sarabia, Alfonso M; De Manuel Keenoy, Esteban; Viart, Frédéric; Okubo, Kimihiro; Sanchez-Borges, Mario; Dubakiene, Ruta; Courbis, Anne Lise; Bourrez, Jean Marc; Gaga, Mina; Thibaudon, Michel; Guzman, Maria Antonieta; Dantas, Carina; Menditto, Enrica; Pinnock, Hilary; Keil, Thomas; De Feo, Giulia; Gotua, Maia; Silva, J da; Laune, Daniel; Williams, Dennis M; Zeng, Stéphane; Montefort, Steve; Hajjam, Jawad; Bedbrook, Anna; González Diaz, Sandra; Neou, Angelo; Marien, Gert; Marshall, Gailen D; Malva, Joao; Vandenplas, Olivier; Valiulis, Arunas; Akdis, Cezmi A; Pali-Schöll, Isabella; Kalayci, Omer; Gamkrelidze, Amiran; Nyembue Tshipukane , Dieudonne; Zidarn, Mihaela; Muraro, Antonella; Costa, Elísio; Bonniaud, Philippe; Kaidashev, Igor; Matricardi, Poalo M; Menditto, Enrica; Melo-Gomes, Elisabete; Waserman, Susan; Bennoor, Kazi Saifuddin; Prokopakis, Emmanuel P; Di Capua, Stefania; Jung, Ki-Suck; Plavec, Davor; Neffen, Hugo; Papadopoulos, Nikos; Gemicioglu, Bilun; Lipworth, Brian; Mihaltan, Florin; Mohammad, Yousser; Yorgancıoglu, Arzu; Bouchard, Jacques; Sisul, Juan-Carlos; Leonardini, Lisa; Rottem, Menahenm; Pfaar, Oliver; Ventura, Maria Teresa; Ivancevich, Juan C; Panzner, Peter; Brusselle, Guy; Zhang, Luo; Carriazo, Ana M; Manning, Patrick; Stellato, Cristina; Romano, Antonino; Bialek, Slawomir; Kull, Inger; Raciborski, Filip; Mullol, Joaquin; Klimek, Ludger; Meltzer, Eli O; Spranger, Otto; Brozek, Jan; Boulet, Louis P; Somekh, David; Valovirta, Erkka; Rolland, Christine; Mogica Martinez, Maria Dolores; Valenta, Rudolf; Casale, Thomas; Benveniste, Samuel; O'Hehir, Robyn; Mösges, Ralf; Eller, Esben; Schmid-Grendelmeir, Peter; Briedis, Vitalis; Popov, Ted A; Napoli, Luigi; O'B Hourihane, John; Joos, Guy; Chavannes, Niels; Picard, Robert; Naclerio, Robert; Bewick, Michael; Sousa, Jaime Correia de; Dokic, Dejan; Yiallouros, Panayiotis; Cruz, Alvaro; Loureiro, Claudia C; Phillips, Jim; To, Teresa; Valentin Rostan, Marylin; Tomazic, Peter Valentin; Carr, Warner; Khaitov, Mussa; Bosse, Isabelle; Okamoto, Yoshitaka; Czarlewski, Wienczyslawa; Pereira, Ana-Maria; Le Thi Tuyet, Lan; Zernotti, Mario; Fink-Wagner, Antjie; Masjedi, Mohamed R; Rosario, Nelson; Vezzani, Giorgio; Wagenmann, Martin; Viegi, Giovanni; Cingi, Cemal; Louis, Renaud; Vasankari, Tuula; Rodo, Xavier; Toppila-Salmi, Sanna; Illario, Maddalena; Ierodiakonou, Despo; Park, Hae-Sim; Fokkens, Wytske J; Wickman, Magnus; Wroczynski, Piotr; D'Amato, Gennaro; Maspero, Jorge F; Sova, Milan; Bateman, Eric; Roller-Wirnsberger, Regina E; Kowalski, Marek L; Rajabian-Söderlund, Rojin; Pham-Thi, Nhân; Emuzyte, Regina; Dedeu, Antoni; Mercier, Jacques; Valero, Antonio; Arnavielhe, Sylvie; Mahboub, Bassam; Sooronbaev, Talant; Walker, Samantha; Humbert, Marc; Gomez, Maximiliano; Wallace, Dana; Blain, Hubert; Melén, Erik; El-Gamal, Yaya; Khaltaev, Nikolai; Bosnic-Anticevich, Sinthia; Wong, Gary; Canonica, Giorgo W; Milenkovic, Branislava; Mair, Alpana; Linnemann, Désirée Larenas; Zar, Heather J; Onorato, Gabrielle; Pépin, Jean-Louis; Tsiligianni, Ioanna; Zhong, Nan SBackground: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted “patient activation”, (ii) Implementation of care pathways by pharmacists and (iii) Nextgeneration guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.