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Advisor(s)
Abstract(s)
A fibrose pulmonar consiste na degradação compacta da matriz extracelular no
interstício dos pulmões associada à destruição do parênquima pulmonar, resultando
na perda de função pulmonar, podendo ser esta uma das consequências da Síndrome
de Dificuldade Respiratória Aguda (SDRA) em doentes internados numa Unidade de
Cuidados Intensivos (UCI). Tendo por base o exposto, objetiva-se validar evidência
científica sobre a fibrose pulmonar em doentes pós SDRA. Foi realizada uma revisão
literária segundo a metodologia proposta pela Joanna Briggs Institute. Procedeu-se à
pesquisa de estudos datados entre 2014 e 2022, nos idiomas português e inglês,
recorrendo às seguintes bases de dados: Medline/Pubmed, Web of Science e LILACS.
Dois revisores independentes realizam a avaliação crítica, extração e síntese dos dados.
Foram incluídos cinco estudos. Os resultados dos mesmos evidenciaram casos de
fibrose pulmonar em doentes pós SDRA, com maior duração do uso de ventilador e
com tempo na UCI significativamente mais elevado. A mortalidade hospitalar é
também mais elevada no grupo de doentes com fibrose pulmonar.
Pulmonary fibrosis consists of the compact degradation of the extracellular matrix in the interstitium of the lungs associated with the destruction of the lung parenchyma, resulting in loss of lung function, which may be one of the consequences of Acute Respiratory Distress Syndrome (ARDS) in patients admitted to a Care Unit. Intensives (ICU). Based on the above, the objective is to validate scientific evidence on pulmonary fibrosis in post-ARDS patients in ICU. A systematic review was carried out according to the methodology proposed by the Joanna Briggs Institute. A search was carried out on studies dated between 2014 and 2022, in Portuguese and English, using the following databases: Medline/Pubmed, Web of Science and LILACS. Two independent reviewers perform the critical evaluation, extraction and synthesis of the data. Five studies were included. Their results showed cases of pulmonary fibrosis in post-ARDS patients, with longer duration of ventilator use and significantly longer ICU time. Hospital mortality is also higher in the group of patients with pulmonary fibrosis.
Pulmonary fibrosis consists of the compact degradation of the extracellular matrix in the interstitium of the lungs associated with the destruction of the lung parenchyma, resulting in loss of lung function, which may be one of the consequences of Acute Respiratory Distress Syndrome (ARDS) in patients admitted to a Care Unit. Intensives (ICU). Based on the above, the objective is to validate scientific evidence on pulmonary fibrosis in post-ARDS patients in ICU. A systematic review was carried out according to the methodology proposed by the Joanna Briggs Institute. A search was carried out on studies dated between 2014 and 2022, in Portuguese and English, using the following databases: Medline/Pubmed, Web of Science and LILACS. Two independent reviewers perform the critical evaluation, extraction and synthesis of the data. Five studies were included. Their results showed cases of pulmonary fibrosis in post-ARDS patients, with longer duration of ventilator use and significantly longer ICU time. Hospital mortality is also higher in the group of patients with pulmonary fibrosis.
Description
Keywords
Fibrose Pulmonar Síndrome de Dificuldade Respiratória Unidade Cuidados Intensivos