Design and production of sintered β-tricalcium phosphate 3D scaffolds for bone tissue regeneration

Santos, Carlos Filipe Lopes; Silva, Abílio P.; Lopes, Luís; Pires, Inês; Correia, Ilídio Joaquim Sobreira

http://hdl.handle.net/10400.6/4633

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Authors

Santos, Carlos Filipe Lopes

Silva, Abílio P.

Lopes, Luís

Pires, Inês

Correia, Ilídio Joaquim Sobreira

Abstract(s)

The characteristics of sintered β-tricalcium phosphate (β-TCP) scaffolds produced by 3D printing were studied by means of X-ray diffraction, Scanning Electron Microscopy, Fourier transform infrared spectroscopy, uniaxial compression tests and cytotoxicity tests, using human osteoblast cells. The results reported include details of the β-TCP scaffolds' porosity, density, phase stability, mechanical behavior and cytotoxic profile. Collectively, these properties are fundamental for the future application of these scaffolds as bone substitutes for individualized therapy.

Keywords

β-TCP scaffolds Bone regeneration Computer Aided Tissue Engineering Individualized scaffolds Rapid prototyping

URI

http://hdl.handle.net/10400.6/4633

Citation

Santos, C.F.L., Silva, A.P., Lopes. L., Pires, I. e Correia, I.J. (2012) “Design and production of sintered β-tricalcium phosphate 3D scaffolds for bone tissue regeneration”, Materials Science & Engineering C - Materials for Biological Applications, Vol. 32(5), pp. 1293-1298