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Functionalization of graphene family nanomaterials for application in cancer therapy

2018-07-17Journal article Restricted access
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dc.contributor.authorDiogo, Duarte Miguel de Melo
dc.contributor.authorSousa, Ana Rita Lima
dc.contributor.authorAlves, Cátia
dc.contributor.authorCosta, Elisabete C.
dc.contributor.authorLouro, Ricardo
dc.contributor.authorCorreia, Ilídio Joaquim Sobreira
dc.date.accessioned2018-08-23T09:03:37Z
dc.date.available2018-08-23T09:03:37Z
dc.date.issued2018-07-17
dc.description.abstractGraphene family nanomaterials’ (GFN) ability to interact with near-infrared light has propelled their application in cancer photothermal therapy. Furthermore, the graphitic lattice of GFN can adsorb different types of molecules, which has motivated their use in cancer drug delivery. However, the direct application of GFN in cancer therapy is severely hindered by their poor colloidal stability, sub-optimal safety, inefficient tumor uptake and non-selectivity towards cancer cells. To overcome these limitations, GFN have been functionalized with different types of materials. This review is focused on the different functionalizations used in the design of GFN aimed for application in cancer therapy, disclosing their role on surpassing the critical issues related to GFN-based therapies.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationde Melo-Diogo, D., Lima-Sousa, R., Alves, C.G., Costa, E.C., Louro, R.O., e Correia, I.J. (2018) "Functionalization of Graphene Family Nanomaterials for Application in Cancer Therapy", Colloids and Surfaces B: Biointerfaces, Vol. 171, pp. 260-275.pt_PT
dc.identifier.doi10.1016/j.colsurfb.2018.07.030pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/5683
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationHealth Sciences Research Centre
dc.relationMULTIFUNCTIONAL GRAPHENE-OXIDE NANOCARRIERS FOR DRUG DELIVERY AND PHOTOTHERMAL THERAPY OF LUNG CANCER
dc.relation3D multicellular spheroids as high throughput platforms to screen novel combinatory therapies for treatment of pancreatic cancer
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0927776518304776pt_PT
dc.subjectCancer Therapypt_PT
dc.subjectTumorspt_PT
dc.subjectGraphene oxidept_PT
dc.subjectPhotothermal therapypt_PT
dc.subjectNanostructurespt_PT
dc.titleFunctionalization of graphene family nanomaterials for application in cancer therapypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleHealth Sciences Research Centre
oaire.awardTitleMULTIFUNCTIONAL GRAPHENE-OXIDE NANOCARRIERS FOR DRUG DELIVERY AND PHOTOTHERMAL THERAPY OF LUNG CANCER
oaire.awardTitle3D multicellular spheroids as high throughput platforms to screen novel combinatory therapies for treatment of pancreatic cancer
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F00709%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F103506%2F2014/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F103507%2F2014/PT
oaire.citation.endPage275pt_PT
oaire.citation.startPage260pt_PT
oaire.citation.titleColloids and Surfaces B: Biointerfacespt_PT
oaire.citation.volume171pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMiguel de Melo Diogo
person.familyNameSousa
person.familyNameAlves
person.familyNameda Rocha Costa
person.familyNameLouro
person.familyNameJoaquim Sobreira Correia
person.givenNameDuarte
person.givenNameAna Rita Lima
person.givenNameCátia Gomes
person.givenNameElisabete Cristina
person.givenNameRicardo
person.givenNameIlídio
person.identifierC2z5x04AAAAJ
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-id9C10-9BD8-634E
person.identifier.ciencia-idBD19-68AA-7099
person.identifier.ciencia-id8317-7EF2-24C8
person.identifier.ciencia-idB314-4CF0-6633
person.identifier.ciencia-idF610-7373-DC81
person.identifier.orcid0000-0001-9984-3603
person.identifier.orcid0000-0003-4764-1967
person.identifier.orcid0000-0001-7066-3051
person.identifier.orcid0000-0002-0490-0095
person.identifier.orcid0000-0002-2392-6450
person.identifier.orcid0000-0003-1613-9675
person.identifier.ridB-1125-2019
person.identifier.scopus-author-id56266511300
person.identifier.scopus-author-id57201215315
person.identifier.scopus-author-id57201213407
person.identifier.scopus-author-id55805850100
person.identifier.scopus-author-id6603724134
person.identifier.scopus-author-id7003557499
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
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