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Julbernardia paniculata and Pterocarpus angolensis: From Ethnobotanical Surveys to Phytochemical Characterization and Bioactivities Evaluation

2020Journal article Open access
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dc.contributor.authorSantos, Eugénia Solange
dc.contributor.authorLuís, Ângelo
dc.contributor.authorGonçalves, Joana
dc.contributor.authorRosado, Tiago
dc.contributor.authorPereira, L.
dc.contributor.authorGallardo, Eugenia
dc.contributor.authorDuarte, A. P.
dc.date.accessioned2020-04-23T09:14:26Z
dc.date.available2020-04-23T09:14:26Z
dc.date.issued2020
dc.description.abstractJulbernardia paniculata and Pterocarpus angolensis are two plant species with important application in African traditional medicine, particularly in Angola, in the treatment of several diseases. However, scientific studies concerning these species are scarce. The goal of this work was to know better which medicinal approaches are used by the Huíla population in Angola by means of ethnobotanical surveys. Furthermore, extracts of both plants were phytochemically characterized. Antioxidant, anti-inflammatory, wound-healing activities, and potential cytotoxicity were also studied. With this study it was possible to verify that 67% of the individuals that use medicinal plants are women, and their main therapeutic uses are the treatment of problems of the digestive system and skin disorders. Barks of J. paniculata and leaves of P. angolensis are the most often used plant parts. Through high-performance liquid chromatography coupled to diode-array detector (HPLC-DAD) and GC-MS it was possible to characterize the chemical composition of the two species, which are rich in phenolic compounds, terpenes, terpenoids, sesquiterpenoids and fatty acids. Both plants showed to possess antioxidant, anti-inflammatory proprieties, and wound-healing activity. To the best of our knowledge, this is the most comprehensive study of these two species and the first ethnobotanical and ethnopharmacological study of medicinal plants from this region of Angola.pt_PT
dc.description.sponsorshipInstituto Nacional de Gestão de Bolsas de Estudo (INAGBE) from República de Angola (Presentation Guide Number: 459/2016)pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/molecules25081828pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/10263
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationHealth Sciences Research Centre
dc.subjectJulbernardia paniculatapt_PT
dc.subjectPterocarpus angolensispt_PT
dc.subjectEthnobotanical surveyspt_PT
dc.subjectHPLC-DADpt_PT
dc.subjectGC-MSpt_PT
dc.subjectPhytochemicalspt_PT
dc.subjectWound-healing activitypt_PT
dc.titleJulbernardia paniculata and Pterocarpus angolensis: From Ethnobotanical Surveys to Phytochemical Characterization and Bioactivities Evaluationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleHealth Sciences Research Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00709%2F2020/PT
oaire.citation.issue8pt_PT
oaire.citation.startPage1828pt_PT
oaire.citation.titleMoleculespt_PT
oaire.citation.volume25pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameSantos Luís
person.familyNameGonçalves
person.familyNameRosado
person.familyNamePereira
person.familyNameGallardo
person.familyNameDuarte
person.givenNameÂngelo Filipe
person.givenNameJoana
person.givenNameTiago
person.givenNameLuísa
person.givenNameEugenia
person.givenNameAna Paula
person.identifier2664004
person.identifier908303
person.identifier1255684
person.identifier.ciencia-id3D14-798B-65D3
person.identifier.ciencia-idC21B-DCC7-1C44
person.identifier.ciencia-id4F15-1868-D001
person.identifier.ciencia-idF617-5CA5-EF61
person.identifier.ciencia-idBC15-D376-80FE
person.identifier.orcid0000-0003-0712-6522
person.identifier.orcid0000-0001-8702-415X
person.identifier.orcid0000-0003-0469-2895
person.identifier.orcid0000-0002-9068-4607
person.identifier.orcid0000-0002-1802-8998
person.identifier.orcid0000-0003-3333-5977
person.identifier.ridM-7410-2017
person.identifier.ridB-5904-2009
person.identifier.scopus-author-id57191891820
person.identifier.scopus-author-id10839238300
person.identifier.scopus-author-id24721485300
person.identifier.scopus-author-id7102602131
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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