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New neo-Clerodanes fromTinnea antiscorbutica Welv

2013-10-04Journal article Restricted access
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dc.contributor.authorBorges, Cristina M. P.
dc.contributor.authorMendonça, Dina
dc.contributor.authorPinheiro, Sandra C. S.
dc.contributor.authorVieira, Liliana
dc.contributor.authorMendonça, António
dc.contributor.authorGaspar, Jorge F.
dc.contributor.authorMartins, Célia
dc.contributor.authorDiakanamwa, Carlos
dc.contributor.authorRueff, José
dc.date.accessioned2022-08-23T10:13:22Z
dc.date.available2022-08-23T10:13:22Z
dc.date.issued2013-10-04
dc.description.abstractThree new neo-clerodanes, antiscorbuticane A, antiscorbuticane B and antiscorbuticane C, and known compounds glutinol, friedelin, 5,7-dihydroxyflavanone (pinocembrin), 5-hydroxy-3,6,7,4'-tetramethoxyflavone, 5-hydroxy-3,6,7,3',4'-pentamethoxyflavone (artemetin), 5,4'-dihydroxy-3,6,7,3'-tetramethoxyflavone (penduletin) and 5,3',4'-trihydroxy-3,6,7-trimethoxyflavone (chrysosplenol D), were isolated from the methanol extract of Tinnea antiscorbutica. Antiscorbuticane B exhibited no mutagenic activity at doses of up to 250 µg per plate (Ames test) and did not induce micronucleus formation in the V79 cell line at doses of up to 100 µg /mL.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBorges, C. M. P., De Mendonça, D. I. M. D., Pinheiro, S. C. S., Vieira, L., Mendonça, A. J. G., Gaspar, J. F., . . . Rueff, J. (2013). New neo-clerodanes from tinnea antiscorbutica welv. Journal of the Brazilian Chemical Society, 24(12), 1950-1956. doi:10.5935/0103-5053.20130244pt_PT
dc.identifier.doi10.5935/0103-5053.20130244pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/12306
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBrazilian Chemical Societypt_PT
dc.relationChemical composition of medicinal plants from Angola
dc.relation.publisherversionhttps://www.scielo.br/j/jbchs/a/sdcKSQfvp9FSzqMC9VcYvny/?lang=en&format=htmlpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectTinnea antiscorbuticapt_PT
dc.subjectNeo-clerodanespt_PT
dc.subjectMutagenic activitypt_PT
dc.subjectCytotoxic activitypt_PT
dc.subjectGenotoxicitypt_PT
dc.titleNew neo-Clerodanes fromTinnea antiscorbutica Welvpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleChemical composition of medicinal plants from Angola
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POCI/POCTI%2FQUI%2F39380%2F2001/PT
oaire.citation.endPage1956pt_PT
oaire.citation.startPage1950pt_PT
oaire.citation.titleJournal of the Brazilian Chemical Societypt_PT
oaire.citation.volume24pt_PT
oaire.fundingStreamPOCI
person.familyNameMendonca
person.familyNamede Oliveira Vieira
person.familyNameMendonça
person.familyNameRueff
person.givenNameDina
person.givenNameLiliana Isabel
person.givenNameAntónio
person.givenNameJosé
person.identifier.ciencia-idB112-0768-4411
person.identifier.ciencia-idDF12-2022-CEC7
person.identifier.ciencia-id2419-6E20-F958
person.identifier.ciencia-id0E15-908D-EA21
person.identifier.orcid0000-0001-9511-2942
person.identifier.orcid0000-0002-2759-5935
person.identifier.orcid0000-0001-8069-0440
person.identifier.orcid0000-0002-8456-7295
person.identifier.ridAFO-4571-2022
person.identifier.ridI-3093-2012
person.identifier.scopus-author-id6506834578
person.identifier.scopus-author-id56890866600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctcopyright cedido à editora - ©2013 Sociedade Brasileira de Químicapt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationc5ae631b-1ee7-4d88-af70-eda0a565f4b7
relation.isAuthorOfPublication1204d132-ac19-4292-a836-7fb568e58ef5
relation.isAuthorOfPublicationfbccceb8-2850-4fe1-ae4f-4aeded7bf32a
relation.isAuthorOfPublicationc1ec817d-b074-4fda-a72d-fca9c1d72617
relation.isAuthorOfPublication.latestForDiscovery1204d132-ac19-4292-a836-7fb568e58ef5
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