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Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia

2020Journal article Open access
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dc.contributor.authorGuedes, Renata R.
dc.contributor.authorKieling, Carlos
dc.contributor.authorSantos, Jorge Luiz dos
dc.contributor.authorRocha, Carolina da
dc.contributor.authorSchwengber, Fernando
dc.contributor.authorAdami, Marina R.
dc.contributor.authorChedid, Marcio F.
dc.contributor.authorVieira, Sandra M. G.
dc.date.accessioned2020-02-05T11:47:16Z
dc.date.available2020-02-05T11:47:16Z
dc.date.issued2020
dc.descriptionVery few prior studies have investigated the presence of ascites as a prognostic factor in children with cirrhosis. To the best of our knowledge, there are no prior studies evaluating the relationship between severity of ascites and patient survival in children with biliary atresia and cirrhosis.Clinically detectable ascites is associated with decreased 1-year survival of children with biliary atresia. These patients should be treated with caution and prioritized for liver transplantation.pt_PT
dc.description.abstractBackground Very few prior studies have investigated the presence of ascites as a prognostic factor in children with cirrhosis. To the best of our knowledge, there are no prior studies evaluating the relationship between severity of ascites and patient survival in children with biliary atresia and cirrhosis. Aims To evaluate the association between severity of ascites and survival of children with cirrhosis and biliary atresia. Methods All children with cirrhosis secondary to biliary atresia evaluated at our institution from 2000 to 2014 were included in this study. Patients were classified into four groups: NA = no ascites; A1 = grade 1 ascites; A2 = grade 2 ascites; and A3 = grade 3 ascites. The primary endpoint of the study was mortality within the first year after patient inclusion. Ninetyday mortality was also evaluated. Prognostic factors related to both endpoints also were studied. [...]pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1007/s10620-019-06029-zpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/9023
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectAscitespt_PT
dc.subjectChronic liver diseasept_PT
dc.subjectLiver transplantpt_PT
dc.subjectPediatric patientspt_PT
dc.subjectPortal hypertensionpt_PT
dc.subjectSurvivalpt_PT
dc.titleSeverity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresiapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleDigestive Diseases and Sciencespt_PT
person.familyNameRostirola Guedes
person.familyNameKieling
person.familyNamedos Santos
person.givenNameRenata
person.givenNameCarlos
person.givenNameJorge Luiz
person.identifier.orcid0000-0001-6634-1391
person.identifier.orcid0000-0002-6564-3950
person.identifier.orcid0000-0002-3839-0222
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationdf76fd62-d8e7-4fa0-b091-2be853004a43
relation.isAuthorOfPublication0169bad7-fe6d-4f78-9417-5692b7fb6161
relation.isAuthorOfPublicatione2e81f33-a7b7-448c-a479-81afd7ca3378
relation.isAuthorOfPublication.latestForDiscoverydf76fd62-d8e7-4fa0-b091-2be853004a43

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