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Abstract(s)
O recurso à imagem de fluorescência por verde de indocianina tem sido cada vez mais
utilizado para orientação terapêutica no intraoperatório da cirurgia colorretal na última
década. A sua aplicação abrange vários campos, nomeadamente na prevenção da
deiscência anastomótica, na marcação do gânglio sentinela e da árvore linfática e na
caracterização da doença metastática colorretal. O objetivo desta tese foi investigar as
indicações atuais e os resultados da imagem de fluorescência por verde de indocianina
na cirurgia colorretal.
Para a elaboração desta revisão de literatura, foi realizada uma pesquisa bibliográfica na
base de dados eletrónica PubMed entre janeiro de 2017 e dezembro de 2022 e foram
selecionados artigos escritos em língua inglesa, espanhola e portuguesa. Foram incluídas
meta-análises e revisões sistemáticas disponíveis sobre a cirurgia colorretal e o uso da
imagem de fluorescência por verde de Indocianina. A análise da literatura revelou que
apesar do ainda baixo nível de evidência, os resultados da utilização da imagem de
fluorescência por verde de indocianina na cirurgia colorretal são interessantes e
encorajadores especialmente na avaliação da perfusão vascular da anastomose, no
sentido de diminuir quer a taxa de deiscência associada quer a alta morbimortalidade,
no mapeamento do gânglio sentinela e na caracterização da metastização do carcinoma
colorretal.
Os estudos sugerem que a imagem de fluorescência por verde de indocianina é uma
modalidade segura e promissora na cirurgia colorretal. Mais estudos serão necessários
para validar a utilização desta técnica na prática habitual da cirurgia colorretal.
The use of indocyanine green fluorescence imaging has been increasingly employed for therapeutic guidance during intraoperative colorectal surgery in the last decade. Its application covers various fields, particularly in the prevention of anastomotic leaks, marking the sentinel lymph node and lymphatic tree, and characterizing colorectal metastatic disease. The aim of this thesis was to investigate the current indications and outcomes of indocyanine green fluorescence imaging in colorectal surgery. For the preparation of this literature review, a bibliographic search was conducted on the PubMed electronic database between January 2017 and December 2022, and articles written in English, Spanish, and Portuguese were selected. Meta-analyses and systematic reviews available on colorectal surgery and the use of indocyanine green fluorescence imaging were included. Literature analysis revealed that despite the still low level of evidence, the results of using indocyanine green fluorescence imaging in colorectal surgery are interesting and encouraging, especially in assessing vascular perfusion of the anastomosis, aiming to reduce both the associated anastomotic leak rate and its high morbidity and mortality, in sentinel lymph node mapping, and in characterizing colorectal carcinoma metastasis. Studies suggest that indocyanine green fluorescence imaging is a safe and promising modality in colorectal surgery. Further studies will be necessary to validate the use of this technique in routine colorectal surgical practice.
The use of indocyanine green fluorescence imaging has been increasingly employed for therapeutic guidance during intraoperative colorectal surgery in the last decade. Its application covers various fields, particularly in the prevention of anastomotic leaks, marking the sentinel lymph node and lymphatic tree, and characterizing colorectal metastatic disease. The aim of this thesis was to investigate the current indications and outcomes of indocyanine green fluorescence imaging in colorectal surgery. For the preparation of this literature review, a bibliographic search was conducted on the PubMed electronic database between January 2017 and December 2022, and articles written in English, Spanish, and Portuguese were selected. Meta-analyses and systematic reviews available on colorectal surgery and the use of indocyanine green fluorescence imaging were included. Literature analysis revealed that despite the still low level of evidence, the results of using indocyanine green fluorescence imaging in colorectal surgery are interesting and encouraging, especially in assessing vascular perfusion of the anastomosis, aiming to reduce both the associated anastomotic leak rate and its high morbidity and mortality, in sentinel lymph node mapping, and in characterizing colorectal carcinoma metastasis. Studies suggest that indocyanine green fluorescence imaging is a safe and promising modality in colorectal surgery. Further studies will be necessary to validate the use of this technique in routine colorectal surgical practice.
Description
Keywords
Deiscência Anastomótica Carcinoma Colorretal Cirurgia Colorretal Gânglio Sentinela Metástases Colorretais Verde de Indocianina