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Prevalence of polypharmacy in the older adult population within primary care in Portugal: a nationwide cross-sectional study

dc.contributor.authorSimões, Pedro Augusto Gomes Rodrigues Marques
dc.contributor.authorSantiago, Luiz Miguel de Mendonça Soares
dc.contributor.authorSimões, José Augusto Rodrigues
dc.date.accessioned2020-03-11T09:27:03Z
dc.date.available2020-03-11T09:27:03Z
dc.date.issued2020-03-09
dc.description.abstractIntroduction Polypharmacy is commonly defined as the simultaneous use of five or more medications; however, there is a lack of consensus regarding the most appropriate definition. It is a significant predictor of morbidity and mortality. The aim of this study was to determine the prevalence of polypharmacy in the population of older adults attending primary care in Portugal and to identify associated sociodemographic and clinical factors. Material and methods We conducted a cross-sectional, analytical study in primary care centres from the five Portuguese healthcare administrative regions and the two autonomous regions. We used a random sample of 757 older adult patients provided by the information department of the ministry of health (SPMS) and family doctors from the autonomous regions. Data collection occurred in March 2018. The variables utilised were sociodemographic characteristics, clinical profile and medication. For each patient, polypharmacy was measured either by the concurrent use of ≥ 5 drugs or by the median number of drugs at the time of data collection. Logistic regression analyses were performed to determine associations between polypharmacy and other variables. Results Polypharmacy (≥ 5 drugs) was present in 77% of the sample. A cut-off of over the median number of drugs was present in 55%. The likelihood of having polypharmacy increased significantly with age (OR = 1.05 (1.02–1.08)), number of chronic health problems (OR = 1.24 (1.07–1.45)) and number of prescribers (OR = 4.71 (3.42–6.48)). Cardiovascular, metabolic and musculoskeletal medications were the most commonly involved in polypharmacy. Conclusions Polypharmacy was a very common occurrence in Portugal. Future primary healthcare policies should address polypharmacy.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationSimões PA, Santiago L, Simões JA. Prevalence of polypharmacy in the older adult population within primary care in Portugal: a nationwide cross-sectional study. Archives of Medical Science. 2020. doi:10.5114/aoms.2020.93537.pt_PT
dc.identifier.doi10.5114/aoms.2020.93537pt_PT
dc.identifier.issn1734-1922
dc.identifier.urihttp://hdl.handle.net/10400.6/9948
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTermediapt_PT
dc.relation.publisherversionhttps://www.termedia.pl/Prevalence-of-polypharmacy-in-the-older-adult-population-within-primary-care-in-Portugal-a-nationwide-cross-sectional-study,19,40068,0,1.html?fbclid=IwAR291I7iJYrJINjSapL9CsUrdjkcclBG2YNvcAahNwAGfjURPekl6PYkOYopt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectPolypharmacypt_PT
dc.subjectAgedpt_PT
dc.subjectMultimorbiditypt_PT
dc.titlePrevalence of polypharmacy in the older adult population within primary care in Portugal: a nationwide cross-sectional studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceWrocław, Polandpt_PT
oaire.citation.titleArchives of Medicial Sciencept_PT
oaire.citation.volume2020pt_PT
person.familyNameSimões
person.familyNameSantiago
person.familyNameRodrigues Simões
person.givenNamePedro Augusto
person.givenNameLuiz Miguel
person.givenNameJosé Augusto
person.identifierL-4695-2016
person.identifier.ciencia-id5111-BB0F-F1F2
person.identifier.ciencia-idAB13-2946-9E61
person.identifier.ciencia-idE419-CED2-38BA
person.identifier.orcid0000-0003-4692-2003
person.identifier.orcid0000-0002-9343-2827
person.identifier.orcid0000-0003-2264-7086
person.identifier.ridO-3955-2017
person.identifier.ridP-9545-2018
person.identifier.scopus-author-id36896116500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication10fb5c22-b65f-4890-ae07-234f5a8b0a18
relation.isAuthorOfPublicationd369cbf1-cade-4706-8910-63a567b6e838
relation.isAuthorOfPublication919b504d-aaa9-40ee-a1a5-40e1e0a57f6f
relation.isAuthorOfPublication.latestForDiscovery919b504d-aaa9-40ee-a1a5-40e1e0a57f6f

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