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Abstract(s)
A presente dissertação de final de curso representa o culminar do curso Mestrado Integrado em Ciências Farmacêuticas na Universidade da Beira Interior. No âmbito da unidade curricular Estágio do Mestrado Integrado em Ciências Farmacêuticas, realizei dois estágios referentes às componentes de farmácia comunitária e farmácia hospitalar, assim como, uma revisão bibliográfica no campo da Toxicologia.
O primeiro capítulo da dissertação em análise diz respeito à componente da revisão bibliográfica que se intitula de “Novos Opioides Sintéticos – Análise e Aspetos Toxicológicos”. As novas substâncias psicoativas são desenhadas para mimetizar os efeitos de grupos terapêuticos psicoativos, que geralmente são drogas de abuso. Novos opioides sintéticos são uma nova tendência neste contexto e representam uma ameaça alarmante para a saúde pública. Este trabalho tem como objetivo identificar e descrever os novos opioides sintéticos em termos de farmacologia, metabolismo, formas disponíveis, bem como seus efeitos tóxicos, destacando as técnicas analíticas disponíveis para sua deteção e quantificação em matrizes biológicas.
O segundo capítulo deste documento é referente ao estágio realizado em farmácia hospitalar, o qual decorreu na Unidade Local de Saúde de Castelo Branco, nos Serviços Farmacêuticos do Hospital Amato Lusitano. Nesta secção, apresenta-se uma descrição pormenorizada da área de atuação farmacêutica em contexto hospitalar, de acordo com a minha experiência, bem como os aspetos legais inerentes à prática em questão.
Numa última instância, este relatório aborda a componente de estágio em farmácia comunitária, a qual foi efetuada na farmácia Ferrer, em Castelo Branco. Neste último capítulo, encontra-se uma apresentação detalhada da realidade farmacêutica no referido campo, bem como a atual conjuntura ética, legal e financeira inerente à mesma.
The present dissertation represents the culmination of the Integrated Master's Degree in Pharmaceutical Sciences at the University of Beira Interior. Regarding the curricular unit Internship of the Integrated Masters Program in Pharmaceutical Sciences, two internships were performed on the areas of community pharmacy and hospital pharmacy, as well as a bibliographical review concerning toxicology science. The first chapter of the dissertation under analysis concerns the bibliographic review component entitled "New Synthetic Opioids - Analysis and Toxicological Aspects". The new psychoactive drugs are designed to mimic the psychoactive therapeutic effects, which are often drugs of abuse. New synthetic opioids are a new trend in this context and pose an alarming threat to public health. This paper aims to identify and describe the new synthetic opioids in terms of pharmacology, metabolism, posology, available forms, as well as their toxic effects, highlighting the analytic techniques available for their detection and quantification in biologic matrices. The second chapter of this document refers to the internship in hospital pharmacy, which was held at the Local Health Unit of Castelo Branco, at the Pharmaceutical Services of the Hospital Amato Lusitano. In this section, a detailed description of the area of pharmaceutical activity in hospital context is presented, according to my experience, as well as the legal aspects inherent to the practice in question. The third chapter presents a report addressing the internship in the community pharmacy, which was developed in Ferrer pharmacy, in Castelo Branco. This last chapter is a detailed presentation of the pharmaceutical reality in the field, also regarding the ethical, financial and legal conjecture presented nowadays.
The present dissertation represents the culmination of the Integrated Master's Degree in Pharmaceutical Sciences at the University of Beira Interior. Regarding the curricular unit Internship of the Integrated Masters Program in Pharmaceutical Sciences, two internships were performed on the areas of community pharmacy and hospital pharmacy, as well as a bibliographical review concerning toxicology science. The first chapter of the dissertation under analysis concerns the bibliographic review component entitled "New Synthetic Opioids - Analysis and Toxicological Aspects". The new psychoactive drugs are designed to mimic the psychoactive therapeutic effects, which are often drugs of abuse. New synthetic opioids are a new trend in this context and pose an alarming threat to public health. This paper aims to identify and describe the new synthetic opioids in terms of pharmacology, metabolism, posology, available forms, as well as their toxic effects, highlighting the analytic techniques available for their detection and quantification in biologic matrices. The second chapter of this document refers to the internship in hospital pharmacy, which was held at the Local Health Unit of Castelo Branco, at the Pharmaceutical Services of the Hospital Amato Lusitano. In this section, a detailed description of the area of pharmaceutical activity in hospital context is presented, according to my experience, as well as the legal aspects inherent to the practice in question. The third chapter presents a report addressing the internship in the community pharmacy, which was developed in Ferrer pharmacy, in Castelo Branco. This last chapter is a detailed presentation of the pharmaceutical reality in the field, also regarding the ethical, financial and legal conjecture presented nowadays.
Description
Keywords
Farmácia Comunitária. Farmácia Hospitalar Novos Opioides Sintéticos Técnicas Laboratoriais Toxicidade