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Abstract(s)
A Epilepsia Benigna Infantil com pontas centro-temporais ou Epilepsia Rolândica é uma das formas mais comuns de epilepsia em crianças e possui uma predominância masculina. Caracteriza-se por crises epilépticas parciais que afectam os órgãos da boca, rosto e voz, e ocorrem principalmente durante o sono. Esta síndrome epiléptica tem o seu início entre os 3 e 13 anos (atingindo o pico aos 9-10 anos) e a remissão surge cerca dos 14-15 anos. É geralmente de fácil controlo com drogas anti-epilépticas.
O Electroencefalograma é a pedra fundamental para o diagnóstico da epilepsia benigna infantil com pontas centro-temporais. Este é representado por uma actividade de base normal, com presença de pontas centro-temporais bifásicas de alta amplitude seguidas por ondas lentas.
Este estudo teve como principal objectivo quantificar a banda gama antes e após as pontas centro-temporais que caracterizam esta síndrome epiléptica. Para tal, foram recolhidos exames electroencefalográficos de alta densidade de 8 crianças com epilepsia benigna infantil com pontas centro-temporais provenientes da consulta de Neurologia Infantil do Centro Hospitalar da Cova da Beira. Destas 8 crianças, 5 (62,5%) eram do sexo masculino e 3 (37,5%) do sexo feminino. A idade média situou-se em 9,63 ± 2,07 anos. Desta amostra populacional 6 (75%) pacientes possuíam actividade epileptiforme unilateral e 2 (25%) actividade epileptiforme bilateral.
Os dados obtidos, demonstraram uma diminuição da potência da banda gama após as pontas centro-temporais nos pacientes com actividade epileptiforme unilateral e um aumento da mesma nos pacientes com actividade epileptiforme bilateral. Observou-se ainda um aumento da banda gama em torno das áreas médias temporais e centrais. Espera-se assim que este estudo venha contribuir para a compreensão da fisiopatologia da epilepsia benigna infantil com pontas centro-temporais.
Benign epilepsy of childhood with centrotemporal spikes or Rolandic Epilepsy is one of the most common forms of epilepsy in children and owns a male predominance. It is characterized by partial epileptic seizures affecting the organs of the mouth, face and voice, and mainly occurs during sleep. This epileptic syndrome got his start between 3 and 13 years (reaching a peak at 9-10 years) and the remission arises about 14-15 years. It is usually easy to control with anti-epileptic drugs. The Electroencephalogram is the cornerstone for the diagnosis of benign epilepsy of childhood with centrotemporal spikes. This is represented by a normal background activity, with the presence of biphasic centrotemporal spikes with high amplitude followed by slow waves. This study had as its main aim to quantify the gamma band before and after the centrotemporal spikes that characterize this epileptic syndrome. For such purpose were collected dense array electroencephalograms of 8 children with benign epilepsy of childhood with centrotemporal spikes from Child Neurology consultation of the Centro Hospitalar da Cova da Beira. These 8 children, 5 (62.5%) were males and 3 female (37.5%). The middle ages stood at 9.63 ± 2.07 years. This population sample 6 (75%) patients had unilateral epileptiform activity and epileptiform activity 2 (25%) bilaterally. The data obtained showed a decrease of power of gamma band after the centrotemporal spikes in patients with unilateral epileptiform activity and an increase of the same in patients with bilateral epileptiform activity. There was also an increase of gamma band around the mid temporal and central areas. It is hoped that this study will contribute for a deeper understanding of the pathophysiology of benign epilepsy of childhood with centrotemporal spikes.
Benign epilepsy of childhood with centrotemporal spikes or Rolandic Epilepsy is one of the most common forms of epilepsy in children and owns a male predominance. It is characterized by partial epileptic seizures affecting the organs of the mouth, face and voice, and mainly occurs during sleep. This epileptic syndrome got his start between 3 and 13 years (reaching a peak at 9-10 years) and the remission arises about 14-15 years. It is usually easy to control with anti-epileptic drugs. The Electroencephalogram is the cornerstone for the diagnosis of benign epilepsy of childhood with centrotemporal spikes. This is represented by a normal background activity, with the presence of biphasic centrotemporal spikes with high amplitude followed by slow waves. This study had as its main aim to quantify the gamma band before and after the centrotemporal spikes that characterize this epileptic syndrome. For such purpose were collected dense array electroencephalograms of 8 children with benign epilepsy of childhood with centrotemporal spikes from Child Neurology consultation of the Centro Hospitalar da Cova da Beira. These 8 children, 5 (62.5%) were males and 3 female (37.5%). The middle ages stood at 9.63 ± 2.07 years. This population sample 6 (75%) patients had unilateral epileptiform activity and epileptiform activity 2 (25%) bilaterally. The data obtained showed a decrease of power of gamma band after the centrotemporal spikes in patients with unilateral epileptiform activity and an increase of the same in patients with bilateral epileptiform activity. There was also an increase of gamma band around the mid temporal and central areas. It is hoped that this study will contribute for a deeper understanding of the pathophysiology of benign epilepsy of childhood with centrotemporal spikes.
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Keywords
Epilepsia benigna - Crianças Epilepsia rolândica Epilepsia - Electroencefalografia - Banda Gama
Pedagogical Context
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Universidade da Beira Interior