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The anti-obesity potential of Ilex paraguariensis: results from a meta-analysis

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dc.contributor.authorLuís, Ângelo
dc.contributor.authorDomingues, F.C.
dc.contributor.authorAmaral, Luísa Maria Jota Pereira
dc.date.accessioned2020-02-04T10:54:07Z
dc.date.available2020-02-04T10:54:07Z
dc.date.issued2019
dc.description.abstractThe dried leaves of Ilex paraguariensis, also known as yerba mate or chimarrão, are used to produce infusions consumed by over 1 million people worldwide, being a traditional drink in several South American countries, particularly, Argentina, Brazil, Uruguay, and Paraguay. The positive effects of I. paraguariensis in obesity have been described and observed in some clinical trials both in animals and in humans. The main goal of this work was to perform a systematic review, complying with the PRISMA (Preferred Reported Items for Systematic Reviews and Meta-Analysis) recommendations, followed by a meta-analysis and Trial Sequential Analysis (TSA), to summarize the results of the recent clinical trials, clarifying the anti-obesity potential of I. paraguariensis. The search for this systematic review was performed on several electronic databases (Pubmed, Web of Science, Scopus, SciELO and Cochrane Library) in July 2017. A total of 22 clinical trials were considered for the quantitative synthesis of the data, totalizing 726 patients enrolled. In conclusion, this systematic review demonstrated the positive effects of I. paraguariensis consumption on the reduction of body weight, body mass index (BMI), and waist circumference of patients, showing its anti-obesity potential.pt_PT
dc.description.sponsorshipBank Santander-Totta with the reference BIPD/ICI-FC-BST-UBI 2016.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1590/s2175-97902019000217615pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/8984
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectIlex paraguariensispt_PT
dc.subjectSystematic reviewpt_PT
dc.subjectMeta-analysispt_PT
dc.subjectClinical trialspt_PT
dc.subjectAnti-obesitypt_PT
dc.titleThe anti-obesity potential of Ilex paraguariensis: results from a meta-analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBrazilian Journal of Pharmaceutical Sciencespt_PT
oaire.citation.volume55pt_PT
person.familyNameLuís
person.familyNameDomingues
person.familyNamePereira
person.givenNameÂngelo Filipe Santos
person.givenNameFernanda
person.givenNameLuísa
person.identifier.ciencia-id3D14-798B-65D3
person.identifier.ciencia-id6514-0498-3E8F
person.identifier.ciencia-id4F15-1868-D001
person.identifier.orcid0000-0003-0712-6522
person.identifier.orcid0000-0002-9540-0853
person.identifier.orcid0000-0002-9068-4607
person.identifier.ridN-7295-2013
person.identifier.scopus-author-id10139481400
person.identifier.scopus-author-id10839238300
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa2d7c872-99db-41e1-9bc9-82c2d47b4661
relation.isAuthorOfPublication8d5fe6e2-21af-4557-9c46-84103254a18a
relation.isAuthorOfPublication604e508e-9f4e-4950-b2a4-1b06c7192afe
relation.isAuthorOfPublication.latestForDiscoverya2d7c872-99db-41e1-9bc9-82c2d47b4661

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