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Predictors of uncontrolled hypertension and antihypertensive medication nonadherence

2010Journal article Open access
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dc.contributor.authorMorgado, Manuel
dc.contributor.authorRolo, Sandra
dc.contributor.authorMacedo, Ana Filipa
dc.contributor.authorPereira, Luísa
dc.contributor.authorCastelo-Branco, Miguel
dc.date.accessioned2011-01-05T01:11:57Z
dc.date.available2011-01-05T01:11:57Z
dc.date.issued2010
dc.descriptionhttp://www.jcdronline.com/text.asp?2010/1/4/196/74263por
dc.description.abstractBackground: Although hypertension is, in most cases, a controllable major risk factor in the development of cardiovascular disease, studies have demonstrated that hypertension remains poorly controlled in Portugal. Our aim was to evaluate the covariates associated with poor blood pressure (BP) control in a Portuguese hypertensive population. Patients and Results: We conducted a cross-sectional survey in a hospital hypertension outpatient clinic, located in the Eastern Central Region of Portugal. Patients attending the clinic from July to September 2009 were asked to participate in a structured interview including medication adherence and knowledge about hypertension. Eligible participants were all adults aged 18 or over with an established diagnosis of arterial hypertension and had been on antihypertensive drug treatment for at least 6 months. Exclusion criteria were dementia, pregnancy, and breastfeeding. Detailed clinical information was prospectively obtained from medical records. A total of 197 patients meeting the inclusion criteria and consenting to participate completed the interview. Of these, only 33.0% had their BP controlled according to the JNC 7 guidelines. Logistic regression analysis revealed three independent predictors of poor BP control: living alone (OR = 5.3, P = 0.004), medication nonadherence (OR = 4.8, P < 0.001), and diabetes (OR = 4.4, P = 0.011). Predictors of medication nonadherence were: unawareness of target BP values (OR = 3.7, P < 0.001), a report of drug side effects (OR = 3.7, P = 0.002), lack of BP monitoring (OR = 2.5, P = 0.015) and unawareness of medication indications (OR = 2.4, P = 0.021), and of hypertension risks (OR = 2.1, P = 0.026). Conclusions: Poor medication adherence, lack of information about hypertension, and side effects should be considered as possible underlying causes of uncontrolled BP and must be addressed in any intervention aimed to improve BP control.por
dc.identifier.doi10.4103/0975-3583.74263
dc.identifier.issn0975-3583
dc.identifier.urihttp://hdl.handle.net/10400.6/656
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherPeng Zhoupor
dc.relation.ispartofseriesVol 1;Issue 4
dc.relation.publisherversionhttp://www.jcdronline.com/text.asp?2010/1/4/196/74263por
dc.subjectAntihypertensivespor
dc.subjectBlood pressure controlpor
dc.subjectHypertensionpor
dc.subjectMedication adherencepor
dc.titlePredictors of uncontrolled hypertension and antihypertensive medication nonadherencepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage202por
oaire.citation.startPage196por
oaire.citation.titleJournal of Cardiovascular Disease Researchpor
person.familyNameNunes Vicente Passos Morgado
person.familyNamePereira
person.familyNameCASTELO-BRANCO CRAVEIRO SOUSA
person.givenNameManuel Augusto
person.givenNameLuísa
person.givenNameMIGUEL
person.identifierAAG-4910-2021
person.identifierF-7869-2010
person.identifier.ciencia-id7617-9FDC-2D9D
person.identifier.ciencia-id4F15-1868-D001
person.identifier.ciencia-idE91D-05E2-A2C1
person.identifier.orcid0000-0003-2112-2835
person.identifier.orcid0000-0002-9068-4607
person.identifier.orcid0000-0002-6191-5912
person.identifier.scopus-author-id55955252600
person.identifier.scopus-author-id10839238300
person.identifier.scopus-author-id36730721300
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication7c614887-225f-44d4-b467-3cc34e44a98b
relation.isAuthorOfPublication604e508e-9f4e-4950-b2a4-1b06c7192afe
relation.isAuthorOfPublication67c51098-b7e8-4164-bcfe-528b50e11bfd
relation.isAuthorOfPublication.latestForDiscovery604e508e-9f4e-4950-b2a4-1b06c7192afe

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