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Advisor(s)
Abstract(s)
Introduction: Polypharmacy is commonly defined as the simultaneous taking of five or more drugs. Deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially inappropriate medications, especially in the elderly. The direct involvement of patients and their caregivers in the choice and administration of drugs has long been known to be very important, but it is not usually applied. The aim of this study is to assess the knowledge of older adults about deprescription, the effect on willingness to have regular medications deprescribed and its quality-of-life outcome.
Methods and analysis: This study protocol comprises three phases. The first two phases will be nationwide
and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of
deprescribing perceived by older adults, as well as their willingness to have regular medications deprescribed and to self-medicate. The third and last phase will be a nonpharmacological randomised clinical study to measure older patients’ acceptance to have regular medications deprescribed and related quality of life.
Ethics and dissemination: The study will be conducted in accordance with the principles expressed in the
Declaration of Helsinki. It has been approved by the Ethics Committee of the University of Beira Interior and
Portuguese National Data Protection Commission. Study results will be published in peer-reviewed journals and presented at national and international conferences. In short, no action will be taken without written consent from patients and doctors.
Trial registration number >NCT03283735.
Description
Artigo inserido no projeto de doutoramento em Ciências da Saúde de Pedro Augusto Gomes Rodrigues Marques Simões, sob a orientação de Luiz Miguel de Mendonça Soares Santiago e de José Augusto Rodrigues Simões
Keywords
Multimorbilidade Polifarmácia