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Authors
Abstract(s)
O presente relatório foi elaborado no âmbito da Unidade Curricular “Estágio” do Mestrado Integrado em Ciências Farmacêuticas na Universidade da Beira Interior e encontra-se dividido em três capítulos.
No primeiro capítulo encontra-se descrita a vertente de farmácia comunitária e as atividades desenvolvidas durante este estágio que teve a duração de doze semanas (480 horas) e reali-zado na Farmácia da Sé, Guarda. Aqui tive a oportunidade de acompanhar todas as etapas do circuito do medicamento, nomeadamente o aprovisionamento, receção de encomendas, armazenamento e dispensa das especialidades farmacêuticas. Neste ambiente pude também participar noutras atividades como a medição de parâmetros bioquímicos e na preparação de medicamentos manipulados.
O segundo capítulo relata as atividades desenvolvidas ao longo de oito semanas (320 horas) de estágio em farmácia hospitalar realizado nos Serviços Farmacêuticos do Centro Hospitalar Cova da Beira, Covilhã. Neste contexto pude testemunhar como os medicamentos são selecio-nados e adquiridos bem como os diversos processos de distribuição a que estão sujeitos em meio hospitalar. Os Serviços Farmacêuticos detêm também responsáveis pela correta condu-ção dos ensaios clínicos que decorrem no Centro Hospitalar Cova da Beira bem como pela preparação de medicamentos manipulados e citotóxicos, acompanhando ainda o estado clíni-co dos doentes onde intervêm ativamente para um prognóstico de sucesso.
O terceiro capítulo é referente ao projeto de investigação intitulado “Estudos de Formulação de Nanoemulsões de Fenitoína” desenvolvido no Centro de Investigação em Ciências da Saúde na Universidade da Beira Interior. Este trabalho teve como objetivo o desenvolvimento de uma nanoemulsão de fenitoína para administração intranasal. Para tal, os excipientes a utili-zar foram selecionados com base em dados bibliográficos e experimentais, sendo a proporção de cada um otimizada experimentalmente. A formulação final foi caracterizada quanto ao tamanho das gotículas, potencial zeta, comportamento reológico e pH.
This report was written as a part of the subject “Estágio” of the Pharmaceutical Sciences’ Masters Degree of University of Beira Interior and it is divided in three chapters. In the first chapter, both the community pharmacy component and the activities developed during this internship, which lasted twelve weeks (480 hours) at Farmácia da Sé, Guarda, are described. I had the opportunity to be a part of all the stages in the medicine circuit: provi-sion, order reception, storage and dispense. I also participated in other activities such as the measurement of biochemical parameters and preparation of compounded medicines. The second chapter reports the activities developed during my eight weeks (320 hours) in-ternship at the Pharmaceutical Services of Centro Hospitalar Cova da Beira, Covilhã. I wit-nessed how medicines are selected and acquired as well as the several distribution processes to which they are subjected to in an hospital environment. The Pharmaceutical Services are also accountable for the correct leading of clinical trials in Centro Hospitalar Cova da Beira and also for the cytotoxic and compound medicine preparation. They also keep up with the patients’ clinical status while actively participating towards a successful prognosis. The third chapter refers to the research project entitled “Phenytoin Nanoemulsion’s Formula-tion Study” conducted at the Health Sciences Research Centre of University of Beira Interior. It aimed to develop a phenytoin nanoemulsion for intranasal administration. To do so, the excipients were selected on the basis of literary and experimental data and their ratio was experimentally optimized. The final formulation was characterized for its droplet’s size, zeta potential, rheological behavior and pH.
This report was written as a part of the subject “Estágio” of the Pharmaceutical Sciences’ Masters Degree of University of Beira Interior and it is divided in three chapters. In the first chapter, both the community pharmacy component and the activities developed during this internship, which lasted twelve weeks (480 hours) at Farmácia da Sé, Guarda, are described. I had the opportunity to be a part of all the stages in the medicine circuit: provi-sion, order reception, storage and dispense. I also participated in other activities such as the measurement of biochemical parameters and preparation of compounded medicines. The second chapter reports the activities developed during my eight weeks (320 hours) in-ternship at the Pharmaceutical Services of Centro Hospitalar Cova da Beira, Covilhã. I wit-nessed how medicines are selected and acquired as well as the several distribution processes to which they are subjected to in an hospital environment. The Pharmaceutical Services are also accountable for the correct leading of clinical trials in Centro Hospitalar Cova da Beira and also for the cytotoxic and compound medicine preparation. They also keep up with the patients’ clinical status while actively participating towards a successful prognosis. The third chapter refers to the research project entitled “Phenytoin Nanoemulsion’s Formula-tion Study” conducted at the Health Sciences Research Centre of University of Beira Interior. It aimed to develop a phenytoin nanoemulsion for intranasal administration. To do so, the excipients were selected on the basis of literary and experimental data and their ratio was experimentally optimized. The final formulation was characterized for its droplet’s size, zeta potential, rheological behavior and pH.
Description
Keywords
Farmácia Comunitária Farmácia Hospitalar Fenitoína Nanoemulsão