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Sodium hyaluronate/chitosan polyelectrolyte complex scaffolds for dental pulp regeneration: synthesis and characterization

2011-06-17Journal article Restricted access
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dc.contributor.authorCoimbra, Patrícia
dc.contributor.authorAlves, Patrícia
dc.contributor.authorValente, Tiago António Martins
dc.contributor.authorSantos, Rita
dc.contributor.authorCorreia, Ilídio Joaquim Sobreira
dc.contributor.authorFerreira, Paula
dc.date.accessioned2018-03-16T16:50:33Z
dc.date.available2018-03-16T16:50:33Z
dc.date.issued2011-06-17
dc.description.abstractIn the present study, small-sized porous scaffolds were obtained from the freeze-drying of sodium hyaluronate/chitosan polyelectrolyte complexes. The obtained materials were characterized by a set of techniques including attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, swelling determination and weight loss studies. The morphology of the scaffolds was observed using scanning electron microscopy. Thermal characterization ofthe scaffolds was also performed by dynamic mechanical thermal analysis and thermogravimetric analysis. Finally, the cytotoxic profile of the prepared scaffolds was evaluated in vitro, using mesenchymal stem cells. The results obtained showed that cells adhered to scaffolds and proliferated. This study also confirmed that the degradation by-products of sodium hyaluronate/chitosan scaffold are noncytotoxic, which is fundamental for its application in the biomedical field.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCoimbra, P., Alves, P., Valente, T.A.M., Santos, R., Correia, I.J. e Ferreira, P. (2011) “Sodium hyaluronate/chitosan polyelectrolyte complex scaffolds for dental pulp regeneration: synthesis and characterization”, International Journal of Biological Macromolecules, Vol. 49(4), pp. 573-579pt_PT
dc.identifier.doi10.1016/j.ijbiomac.2011.06.011pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/4626
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0141813011002388#!pt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectPolyelectrolyte complexespt_PT
dc.subjectPolymeric scaffoldspt_PT
dc.subjectCytotoxicitypt_PT
dc.titleSodium hyaluronate/chitosan polyelectrolyte complex scaffolds for dental pulp regeneration: synthesis and characterizationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FEME-TME%2F103375%2F2008/PT
oaire.citation.endPage579pt_PT
oaire.citation.startPage573pt_PT
oaire.citation.titleInternational Journal of Biological Macromoleculespt_PT
oaire.citation.volume49pt_PT
oaire.fundingStream3599-PPCDT
person.familyNameAlmeida Coimbra
person.familyNameAlves
person.familyNameJoaquim Sobreira Correia
person.familyNameCristina Nunes Ferreira Calvinho
person.givenNamePatrícia Manuela
person.givenNamePatrícia
person.givenNameIlídio
person.givenNamePaula
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-id111E-0CE2-0C3E
person.identifier.ciencia-id341B-551C-19FD
person.identifier.ciencia-idF610-7373-DC81
person.identifier.ciencia-idA119-FFB8-0899
person.identifier.orcid0000-0002-8943-8329
person.identifier.orcid0000-0003-1613-9675
person.identifier.orcid0000-0003-3393-4427
person.identifier.ridI-1004-2013
person.identifier.scopus-author-id12762379800
person.identifier.scopus-author-id7003557499
person.identifier.scopus-author-id55321888200
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication95a46930-ac14-449d-8ddd-db23927062b0
relation.isAuthorOfPublication64a3aef7-8d91-4327-8407-294909eed51a
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relation.isAuthorOfPublication.latestForDiscovery95a46930-ac14-449d-8ddd-db23927062b0
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