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Chitin- and chitosan-based strategies in wound healing

2022-07-01Book part Open access
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dc.contributor.authorCabral, Cátia S. D.
dc.contributor.authorGraça, Mariana F. P.
dc.contributor.authorMoreira, André F.
dc.contributor.authorDiogo, Duarte de Melo
dc.contributor.authorCorreia, I.J.
dc.date.accessioned2023-01-05T15:37:20Z
dc.date.available2025-01-05T01:30:22Z
dc.date.issued2022-07-01
dc.description.abstractNowadays, chronic wounds are still a huge health problem with a high impact on the patients’ quality of life. In this way, the development of an ideal wound dressing is of utmost importance. To accomplish that, researchers have been using natural polymers to produce new types of dressings, that can activate/direct specific cellular responses, leading to an improved healing process. Among the natural polymers, chitin presents notable antibacterial and antiinflammatory properties that are crucial for enhancing the wound healing process. Moreover, chitosan, a deacetylated form of chitin, has been one of the most used biopolymers due to its straightforward processability into different forms, antimicrobial activity, and capacity to promote/accelerate the healing process. This chapter provides an overview of the properties exhibited by chitin and chitosan as well as examples of their application in the development of dressings aimed to improve the healing process.pt_PT
dc.description.sponsorshipThis work was financed by the Foundation for Science and Technology (FCT)/MCTES, through funds from the State Budget, and by the European Regional Development Fund (ERDF), under the Portugal 2020 Program, through the Regional Operational Program of the Center (Centro2020), through the Projects with the reference UIDB/00709/2020 and UIDP/00709/2020. The funding from CENTRO-01-0145-FEDER-028989 and POCI-01-0145-FEDER-031462 is also acknowledged. Duarte de Melo-Diogo acknowledges CENTRO-01- 0145-FEDER-028989 for the funding given on the form of a research contract. Catia S.D. Cabral acknowl- ´ edges his PhD fellowship from FCT (UI/BD/151024/2021). Mariana F.P. Grac¸a acknowledges funding from the grant UBI-Santander/Totta.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/B978-0-323-90514-5.00011-0pt_PT
dc.identifier.isbn978-0-323-90514-5
dc.identifier.urihttp://hdl.handle.net/10400.6/12585
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationHealth Sciences Research Centre
dc.relationHealth Sciences Research Centre
dc.relationBiomimetic 3D scaffolds coated with a thermo-responsive hydrogel containing smart pharmaceuticals nanocarriers aimed for bone tissue regeneration
dc.subjectBiopolymerspt_PT
dc.subjectChitinpt_PT
dc.subjectChitosanpt_PT
dc.subjectSkinpt_PT
dc.subjectWound dressingpt_PT
dc.subjectWound healingpt_PT
dc.titleChitin- and chitosan-based strategies in wound healingpt_PT
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleHealth Sciences Research Centre
oaire.awardTitleHealth Sciences Research Centre
oaire.awardTitleBiomimetic 3D scaffolds coated with a thermo-responsive hydrogel containing smart pharmaceuticals nanocarriers aimed for bone tissue regeneration
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00709%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00709%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//UI%2FBD%2F151024%2F2021/PT
oaire.citation.endPage380pt_PT
oaire.citation.startPage333pt_PT
oaire.citation.titleNatural Polymers in Wound Healing and Repair: From Basic Concepts to Emerging Trendspt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameCabral
person.familyNamePais Graça
person.familyNameMoreira
person.familyNameMiguel de Melo Diogo
person.familyNameJoaquim Sobreira Correia
person.givenNameCátia Solange Duarte
person.givenNameMariana Filipa
person.givenNameAndré Ferreira
person.givenNameDuarte
person.givenNameIlídio
person.identifier1161643
person.identifierC2z5x04AAAAJ
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-id8D18-367B-2572
person.identifier.ciencia-id611F-B0F7-2C15
person.identifier.ciencia-id4C1E-012B-83CE
person.identifier.ciencia-id9C10-9BD8-634E
person.identifier.ciencia-idF610-7373-DC81
person.identifier.orcid0000-0002-4247-4816
person.identifier.orcid0000-0001-7891-6041
person.identifier.orcid0000-0002-0604-2506
person.identifier.orcid0000-0001-9984-3603
person.identifier.orcid0000-0003-1613-9675
person.identifier.scopus-author-id57207108629
person.identifier.scopus-author-id56401521300
person.identifier.scopus-author-id56266511300
person.identifier.scopus-author-id7003557499
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctOs direitos da obra foram cedidos à editorapt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typebookPartpt_PT
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