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Advisor(s)
Abstract(s)
Introdução: A Síndrome de Sjögren Primária é uma doença reumática inflamatória crónica, autoimune, que se manifesta clinicamente por xerostomia e xeroftalmia, devido à infiltração linfocitária das glândulas exócrinas, principalmente glândulas salivares e lacrimais. A ecografia tem sido cada vez mais utilizada na avaliação e seguimento destes doentes visto que é uma técnica imagiológica não invasiva, barata, isenta de radiações e bem aceite pelos doentes.
Objetivos: Revisão de literatura no sentido de avaliar a utilidade da ecografia das glândulas salivares major na avaliação e seguimento dos doentes com Síndrome de Sj?gren Primária.
Metodologia: As palavras-chave “Sj?gren’s Syndrome” “Primary Sj?gren’s Syndrome”, “ultrasonography of the major salivary glands”, “color doppler sonography”, “classification criteria”; “major salivary glands” e “ultrasonography” foram utilizadas para a pesquisa de artigos científicos nas bases de dados PubMed e ResearchGate. Foi também realizada a leitura livros de texto onde este tema era abordado.
Resultados e Discussão: Vários estudos em relação à utilidade da ecografia das glândulas salivares major na avaliação dos doentes com Síndrome de Sj?gren Primária foram realizados e vários parâmetros ecográficos foram descritos como importantes, a saber: a ecogenicidade, a homogeneidade do parênquima glandular, o tamanho/volume, a definição dos bordos das glândulas e a vascularização. A homogeneidade do parênquima glandular é o achado ecográfico que reúne mais consenso entre a comunidade científica como sendo o mais característico de Síndrome de Sj?gren Primária. A vascularização das glândulas salivares pode ser inferida pelo uso de Doppler Cor, que reflete de forma indireta o grau de inflamação. Estudos adicionais são necessários para incorporar esta técnica na prática clínica diária, sendo muito promissora no diagnóstico, na avaliação da progressão da atividade da doença e na monitorização clínica e terapêutica.
Introduction: Primary Sjögren's Syndrome is an autoimmune inflammatory chronic rheumatic disease, which is clinically manifested by xerostomia and xerophthalmia due to lymphocytic infiltration of the exocrine glands, mainly salivary and lacrimal glands. Ultrasound has been increasingly used in the evaluation and follow-up of these patients because it is a noninvasive imaging technique, inexpensive, free of radioation and well accepted by patients. Objetives: Literature review to assess the usefulness of ultrasound of the major salivary glands in the evaluation and follow up of patients with Sj?gren Syndrome Primary. Methodology: The keywords "Sj?gren's Syndrome" "Primary Sj?gren's Syndrome", "ultrasonography of the major salivary glands", "color Doppler sonography," "classification criteria"; "major salivary glands" and "ultrasonography" were used for the research of scientific articles in PubMed and ResearchGate databases. Reading of text books where this topic was discussed. Results and Discussion: Several studies about the use of ultrasound in the assessment of the salivary glands of patients with Primary Sj?gren syndrome were performed and several ultrasound parameters were described as important, namely: echogenicity, homogeneity parenchyma, size / volume, definition of the edges of the salivary glands and vascularization. The homogeneity of the glandular parenchyma is the ultrasound finding which brings more consensus among the scientific community as being the most characteristic of Primary Sj?gren syndrome. The vasculature of the glands can be inferred by the use of color Doppler, which also indirectly reflects the degree of inflammation. Additional studies are needed to incorporate this technique in clinical practice, being very promising in the diagnosis, assessment of the progression of disease activity and clinical and therapeutic monitoring.
Introduction: Primary Sjögren's Syndrome is an autoimmune inflammatory chronic rheumatic disease, which is clinically manifested by xerostomia and xerophthalmia due to lymphocytic infiltration of the exocrine glands, mainly salivary and lacrimal glands. Ultrasound has been increasingly used in the evaluation and follow-up of these patients because it is a noninvasive imaging technique, inexpensive, free of radioation and well accepted by patients. Objetives: Literature review to assess the usefulness of ultrasound of the major salivary glands in the evaluation and follow up of patients with Sj?gren Syndrome Primary. Methodology: The keywords "Sj?gren's Syndrome" "Primary Sj?gren's Syndrome", "ultrasonography of the major salivary glands", "color Doppler sonography," "classification criteria"; "major salivary glands" and "ultrasonography" were used for the research of scientific articles in PubMed and ResearchGate databases. Reading of text books where this topic was discussed. Results and Discussion: Several studies about the use of ultrasound in the assessment of the salivary glands of patients with Primary Sj?gren syndrome were performed and several ultrasound parameters were described as important, namely: echogenicity, homogeneity parenchyma, size / volume, definition of the edges of the salivary glands and vascularization. The homogeneity of the glandular parenchyma is the ultrasound finding which brings more consensus among the scientific community as being the most characteristic of Primary Sj?gren syndrome. The vasculature of the glands can be inferred by the use of color Doppler, which also indirectly reflects the degree of inflammation. Additional studies are needed to incorporate this technique in clinical practice, being very promising in the diagnosis, assessment of the progression of disease activity and clinical and therapeutic monitoring.
Description
Keywords
Critérios de Classificação Ecografia Ecografia das Glândulas Salivares Major Ecografia Doppler Cor Glândulas Salivares Major Síndrome de Sjögren Síndrome de Sjögren Primária