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Development of a screening questionnaire for the study of food allergy in adults

2020Journal article Open access
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dc.contributor.authorLozoya-Ibáñez, Carlos
dc.contributor.authorBelo, João
dc.contributor.authorAfonso, Rosa Marina
dc.contributor.authorPereira, Henrique
dc.contributor.authorRodrigues, Alexandra
dc.contributor.authorBarata, Luís Taborda
dc.date.accessioned2020-10-16T10:09:23Z
dc.date.available2020-10-16T10:09:23Z
dc.date.issued2020
dc.description.abstractBackground & aims: As far as we know, no screening questionnaire has been developed and validated for identification of adverse food reactions in Portuguese-speaking adults, as an initial approach towards the investigation of cases of possible food allergy. Thus, the objective of this study was to develop and validate a screening questionnaire of food allergy in adult Portuguesespeaking patients. Methods: This was a multicentre, cross-sectional study using a simple random sample of 186 adults between 18 and 82 years old from various parts of the centre of Portugal. Intelligibility of the questionnaire was first assessed in 24 patients with confirmed IgE- or non-IgE-mediated food allergy, and in 24 volunteers without food allergies. The 17-item questionnaire was subsequently applied by phone to 78 food allergic patients (66 IgE-mediated and 12 non-IgE mediated) and to 60 non-food allergic volunteers, with subsequent reassessment (re-test). Face and content validity, intelligibility, construct validity, and test-retest reliability (temporal stability) were analysed. Results: Face and content validity allowed item reduction from 30 to 17 items with adequate content validity index >0.78. Construct validity was confirmed in the 66 confirmed IgE-mediated food allergic patients, 12 non-IgE-mediated food allergic patients, and 60 non-allergic patients. Test-Retest Reliability (general temporal stability) of the test had a Spearman correlation coefficient value of 0.845 for the retest. Cohen's Kappa values for the relevant questions were greater than 0.890 for almost all items. No differences were found when sex, age, and volunteers' recruitment origin were analysed. An inverse relationship was found between reliability and retest time interval. Conclusions: Due to the quick and easy implementation, confirmation of face, content and construct validity as well as high temporal reproducibility, this screening questionnaire may be a useful study tool for an initial approach to detection of food allergies in adults.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.waojou.2020.100456pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/10458
dc.language.isoengpt_PT
dc.subjectAdultspt_PT
dc.subjectAdverse food reactionspt_PT
dc.subjectFood allergypt_PT
dc.subjectQuestionnairept_PT
dc.subjectValidationpt_PT
dc.titleDevelopment of a screening questionnaire for the study of food allergy in adultspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue9pt_PT
oaire.citation.startPage100456pt_PT
oaire.citation.titleWorld Allergy Organization Journalpt_PT
oaire.citation.volume13pt_PT
person.familyNamede Morais de Oliveira Belo
person.familyNameAfonso
person.familyNamePereira
person.familyNameTaborda Barata
person.givenNameJoão Luis
person.givenNameRosa Marina
person.givenNameHenrique
person.givenNameLuis
person.identifier1350762
person.identifier104007
person.identifier.ciencia-idDE1B-DF40-D472
person.identifier.ciencia-id321B-A288-E6C6
person.identifier.ciencia-id4011-59E2-6744
person.identifier.ciencia-id1E1F-8A43-055B
person.identifier.orcid0000-0003-4671-4239
person.identifier.orcid0000-0003-2111-6873
person.identifier.orcid0000-0001-9448-682X
person.identifier.orcid0000-0001-6649-8890
person.identifier.ridK-4917-2013
person.identifier.ridAAD-4719-2021
person.identifier.scopus-author-id33867490600
person.identifier.scopus-author-id55680857300
person.identifier.scopus-author-id15128160500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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