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Advisor(s)
Abstract(s)
A via glicolítica é das mais importantes para a manutenção do organismo humano, podendo
ainda estar na base do entendimento de um grande número de patologias. Neste trabalho
apresenta-se uma descrição atualizada da via glicolítica e da sua importância para o organismo
humano, relacionando alterações no seu funcionamento com situações clínicas simples. Para a
realização deste trabalho, foram feitas pesquisas bibliográficas em livros de texto de
bioquímica geral e bioquímica médica, bem como, em bases de dados (Pubmed, Web of Science
e SciELO).
A glicólise consiste na divisão de uma molécula de glicose, que contem seis átomos carbonos,
em duas moléculas com três átomos de carbono. O principal objetivo desta divisão é a obtenção
de energia, que é armazenada em forma de ATP. O 6-fosfato de glicose, é um intermediário da
via glicolítica que serve de precursor para a síntese de outras moléculas em outras vias
metabólicas. O funcionamento da via glicolítica apresenta implicações a vários níveis sobre o
organismo. Assim são consideradas neste trabalho: diabetes mellitus, acidente vascular
cerebral, anemias hemolíticas e cancro.
A Bioquímica fornece subsídios importantes à medicina permitindo-lhe encontrar novas formas
de tratamento para diversas doenças. A relação entre a Bioquímica e a Medicina é muito mais
estreita do que parece.
The glycolytic pathway is one of the most important for the maintenance of the human organism and may also be the basis for understanding a large number of pathologies. This work presents an updated description of the glycolytic pathway and its importance for the human organism, relating changes in its functioning with simple clinical situations. For the accomplishment of this work, bibliographical research was done in textbooks of general biochemistry and medical biochemistry, as well as in databases (Pubmed, Web of Science and SciELO). Glycolysis consists in the division of a glucose molecule, which contains six carbon atoms, into two molecules with three carbon atoms. The main purpose of this division is to obtain energy, which is stored in the form of ATP. Glucose 6-phosphate is an intermediate in the glycolytic pathway that serves as a precursor for the synthesis of other molecules in other metabolic pathways. The functioning of the glycolytic pathway has implications at various levels on the organism. The following are considered in this study: diabetes mellitus, stroke, hemolytic anemia and cancer. Biochemistry provides important subsidies to medicine allowing you to find new ways of treating various diseases. The relationship between biochemistry and medicine is much narrower than it seems.
The glycolytic pathway is one of the most important for the maintenance of the human organism and may also be the basis for understanding a large number of pathologies. This work presents an updated description of the glycolytic pathway and its importance for the human organism, relating changes in its functioning with simple clinical situations. For the accomplishment of this work, bibliographical research was done in textbooks of general biochemistry and medical biochemistry, as well as in databases (Pubmed, Web of Science and SciELO). Glycolysis consists in the division of a glucose molecule, which contains six carbon atoms, into two molecules with three carbon atoms. The main purpose of this division is to obtain energy, which is stored in the form of ATP. Glucose 6-phosphate is an intermediate in the glycolytic pathway that serves as a precursor for the synthesis of other molecules in other metabolic pathways. The functioning of the glycolytic pathway has implications at various levels on the organism. The following are considered in this study: diabetes mellitus, stroke, hemolytic anemia and cancer. Biochemistry provides important subsidies to medicine allowing you to find new ways of treating various diseases. The relationship between biochemistry and medicine is much narrower than it seems.
Description
Keywords
Anemias Hemolíticas Avc Cancro Diabetes Mellitus Via Glicolítica