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Abstract(s)
Este documento encontra-se dividido em trĂȘs partes distintas. A primeira parte, CapĂtulo I, descreve o trabalho de investigação sobre o HPV. Os segundo e terceiro capĂtulos incidem sobre os relatĂłrios de estĂĄgio efetuados em FarmĂĄcia ComunitĂĄria e FarmĂĄcia Hospitalar respetivamente.
CapĂtulo I: O HPV Ă© um vĂrus muito comum e responsĂĄvel por um elevado nĂșmero de infeçÔes. Estima-se que o HPV afete cerca de 630 milhĂ”es de pessoas, resultando numa prevalĂȘncia mundial entre 9 e 13%. Uma infeção por este vĂrus pode progredir para cancro do colo do Ăștero, entre outros cancros. O HPV 16 e o HPV 18 sĂŁo considerados os tipos mais cancerĂgenos. O principal objetivo desta investigação foi estudar a prevalĂȘncia dos tipos de HPV de alto risco em mulheres seguidas na consulta de Ginecologia do CHCB, bem como avaliar alguns fatores de risco para a infeção pelo HPV. A população foi constituĂda por 2278 mulheres, seguidas entre agosto de 2012 e agosto de 2013. Das 228 mulheres com teste de HPV positivo, 72 (31%) tinham idade inferior a 30 anos e apenas 11 mulheres (5%) tinham mais de 60 anos. A maioria das mulheres com teste de HPV positivo nĂŁo apresentava antecedentes de HPV. Das mulheres infetadas, 73% revelou a presença de pelo menos um tipo de HPV de alto risco, excluindo o HPV 16 e o HPV 18. No entanto a percentagem de infeçÔes com o HPV 16 foi significativamente superior do que as infeçÔes provocados pelo HPV 18. Neste estudo, 32 mulheres (14%) apresentaram algum tipo de neoplasia intraepitelial, sendo que a neoplasia intraepitelial cervical de grau 1 (CIN 1) foi a mais representativa. Dos casos de neoplasia intraepitelial cervical de grau 3 (CIN 3), metade revelou a presença de infeção pelo HPV 16. Quanto aos fatores de risco, verificou-se que a idade e o uso de mĂ©todos contracetivos orais revelaram uma correlação com a infeção pelo HPV.
CapĂtulo II: Este capĂtulo relata o meu estĂĄgio curricular em FarmĂĄcia ComunitĂĄria que decorreu na FarmĂĄcia da SĂ©, na Guarda, entre 4 de fevereiro e 2 de maio de 2014. Durante este estĂĄgio tive oportunidade de conhecer o real papel do farmacĂȘutico comunitĂĄrio e das suas diversas funçÔes diĂĄrias.
CapĂtulo III: Este capĂtulo descreve o meu estĂĄgio curricular em FarmĂĄcia Hospitalar, que decorreu entre 5 de maio e 20 de junho de 2014, nos Serviços FarmacĂȘuticos do Hospital Sousa Martins, na Guarda. Com este capĂtulo pretendo descrever as vĂĄrias atividades desempenhadas no quotidiano do farmacĂȘutico hospitalar.
This document is divided into three distinct parts. The first part, Chapter I, describes the research work on HPV. The second and third chapters focus on the internship reports made in Community Pharmacy and Hospital Pharmacy respectively. Chapter I: HPV is a very common virus and it is responsible for a large number of infections. It is estimated that HPV affects about 630 million people resulting in a worldwide prevalence between 9 and 13%. An infection with this virus can progress to cervical cancer, among other cancers. HPV 16 and HPV 18 are considered to be the most carcinogenic types. The main objective of this research was to study the prevalence of the type of high-risk HPV in women followed at the Gynaecology surgery in CHCB, as well as to assess some risk factors for HPV infection. The population consisted of 2278 women followed between August 2012 and August 2013. Of the 228 women with a positive HPV test, 72 (31%) were younger than 30 years old and only 11 women (5%) were older than 60. Most women with HPV positive test had no previous history of HPV. 73% of the infected women revealed the presence of at least one kind of high-risk HPV excluding HPV 16 and HPV 18. However, the percentage of infection with HPV 16 was significantly higher than those induced by HPV 18 infection. In this study, 32 women (14%) presented some type of intraepithelial neoplasia. The cervical intraepithelial neoplasia grade 1 (CIN 1) was the most representative one. Of cervical intraepithelial neoplasia grade 3 (CIN 3) cases, half revealed the presence of HPV 16 infection. Regarding risk factors, it was concluded that the age and use of oral contraceptive methods revealed to have a correlation with HPV infection. Chapter II: This chapter reports my internship in Community Pharmacy that held in the FarmĂĄcia da SĂ©, in Guarda, between the 4th February and the 2nd May 2014. During this internship I got to know the real role of the community pharmacist and his various daily functions. Chapter III: This chapter describes my internship in Hospital Pharmacy, which took place between the 5th May and the 20th June 2014, in Pharmaceutical Services Sousa Martins Hospital, in Guarda. With this chapter I intend to describe the various activities performed in daily life by a hospital pharmacist.
This document is divided into three distinct parts. The first part, Chapter I, describes the research work on HPV. The second and third chapters focus on the internship reports made in Community Pharmacy and Hospital Pharmacy respectively. Chapter I: HPV is a very common virus and it is responsible for a large number of infections. It is estimated that HPV affects about 630 million people resulting in a worldwide prevalence between 9 and 13%. An infection with this virus can progress to cervical cancer, among other cancers. HPV 16 and HPV 18 are considered to be the most carcinogenic types. The main objective of this research was to study the prevalence of the type of high-risk HPV in women followed at the Gynaecology surgery in CHCB, as well as to assess some risk factors for HPV infection. The population consisted of 2278 women followed between August 2012 and August 2013. Of the 228 women with a positive HPV test, 72 (31%) were younger than 30 years old and only 11 women (5%) were older than 60. Most women with HPV positive test had no previous history of HPV. 73% of the infected women revealed the presence of at least one kind of high-risk HPV excluding HPV 16 and HPV 18. However, the percentage of infection with HPV 16 was significantly higher than those induced by HPV 18 infection. In this study, 32 women (14%) presented some type of intraepithelial neoplasia. The cervical intraepithelial neoplasia grade 1 (CIN 1) was the most representative one. Of cervical intraepithelial neoplasia grade 3 (CIN 3) cases, half revealed the presence of HPV 16 infection. Regarding risk factors, it was concluded that the age and use of oral contraceptive methods revealed to have a correlation with HPV infection. Chapter II: This chapter reports my internship in Community Pharmacy that held in the FarmĂĄcia da SĂ©, in Guarda, between the 4th February and the 2nd May 2014. During this internship I got to know the real role of the community pharmacist and his various daily functions. Chapter III: This chapter describes my internship in Hospital Pharmacy, which took place between the 5th May and the 20th June 2014, in Pharmaceutical Services Sousa Martins Hospital, in Guarda. With this chapter I intend to describe the various activities performed in daily life by a hospital pharmacist.
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Keywords
Cancro do Colo do Ătero FarmĂĄcia ComunitĂĄria FarmĂĄcia Hospitalar Fatores de Risco Hpv