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Este trabalho teve como objectivo estudar duas espécies de plantas usadas na medicina tradicional angolana: Solanum incanum e Croton gratissimus.
Os frutos maduros de Solanum incanum foram macerados em metanol, o extracto metanólico foi fracionado por partição líquido-líquido em hexano, clorofórmio e acetato de etilo tendo-se obtido, respectivamente, os extractos de hexano, clorofórmio e acetato de etilo.
Do extracto de acetato de etilo da Solanum incanum foi isolado o ácido cafeico.
A parte aérea da Croton gratissimus foi triturada e de seguida macerada em metanol, o extracto metanólico foi fracionado por partição líquido-líquido em hexano, clorofórmio e acetato de etilo tendo-se obtido, respectivamente, os extractos de hexano, clorofórmio e acetato de etilo.
Foi estudado o extracto de clorofórmio da Croton gratissimus tendo-se isolado o 7-β-metóxiopposit-4(15)-en-1-β-ol.
Os compostos isolados foram completamente elucidados por técnicas de espetroscopia de IV, Espetroscopia de Ressonância Magnética Nuclear (RMN) de 1H e 13C e RMN bidimensional 1H – 1H COSY, HSQC, HMBC e NOESY. Os compostos identificados nunca tinham sido isolados nestas espécies.
This work aimed to study two species of plants used in traditional medicine in Angola: Solanum incanum and Croton gratissimus. The ripe fruits of Solanum incanum were macerated in methanol; the methanol extract was fractionated by liquid-liquid partition in hexane, chloroform and ethyl acetate yielding, respectively, hexane, chloroform and ethyl acetate extracts. Caffeic acid was isolated in the ethyl acetate extract of Solanum incanum. Aerial parts of Croton gratissimus were triturated and then macerated in methanol; the methanol extract was fractionated by liquid-liquid partition in hexane, chloroform and ethyl acetate yielding, respectively, hexane, chloroform and ethyl acetate extracts. Chloroform extract of Croton gratissimus was studied having allowing the isolation of 7-βmethoxyopposit-4(15)-en-1-β-ol. All compounds were fully elucidated by IR spectroscopy, Nuclear Magnetic Resonance Spectroscopy (NMR) and 1H and 13C and 2D-NMR: 1H - 1H COSY, HSQC, HMBC and NOESY. The identified compounds have never been isolated in these species.
This work aimed to study two species of plants used in traditional medicine in Angola: Solanum incanum and Croton gratissimus. The ripe fruits of Solanum incanum were macerated in methanol; the methanol extract was fractionated by liquid-liquid partition in hexane, chloroform and ethyl acetate yielding, respectively, hexane, chloroform and ethyl acetate extracts. Caffeic acid was isolated in the ethyl acetate extract of Solanum incanum. Aerial parts of Croton gratissimus were triturated and then macerated in methanol; the methanol extract was fractionated by liquid-liquid partition in hexane, chloroform and ethyl acetate yielding, respectively, hexane, chloroform and ethyl acetate extracts. Chloroform extract of Croton gratissimus was studied having allowing the isolation of 7-βmethoxyopposit-4(15)-en-1-β-ol. All compounds were fully elucidated by IR spectroscopy, Nuclear Magnetic Resonance Spectroscopy (NMR) and 1H and 13C and 2D-NMR: 1H - 1H COSY, HSQC, HMBC and NOESY. The identified compounds have never been isolated in these species.
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Plantas medicinais - Solanum incanum - Composição química Plantas medicinais - Croton gratissimas - Composição química Medicina tradicional - Plantas medicinais
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Universidade da Beira Interior