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Authors
Abstract(s)
O presente relatório foi elaborado no âmbito da Unidade Curricular “Estágio” e
representa a conclusão do curso de Mestrado Integrado em Ciências Farmacêuticas.
Este encontra-se dividido em três capítulos.
O primeiro capítulo diz respeito ao trabalho de investigação desenvolvido cujo objetivo
foi proceder à operacionalização para Portugal da versão atual dos Critérios
STOPP/START. A população geriátrica é mais vulnerável aos Problemas Relacionados
com Medicamentos devido a alterações farmacocinéticas e farmacodinâmicas, maior
incidência de doenças crónicas e polimedicação. A crescente consciencialização sobre
as consequências da prescrição inapropriada de medicamentos nos idosos, impulsionou
a criação de ferramentas de revisão da medicação para auxiliar os profissionais de
saúde na gestão e monitorização de medicamentos em doentes idosos. Os Critérios
STOPP/START são uma ferramenta desenvolvida em contexto Europeu que indica
Medicamentos Potencialmente Inapropriados e eventuais omissões de prescrição
relevantes nesta faixa etária. Em 2023, foi publicada a terceira e mais recente versão
destes critérios. Portugal é um dos países mais envelhecidos da União Europeia, pelo
que deve incentivar-se a aplicação desta ferramenta na otimização das prescrições em
contexto de geriatria. Para tal, torna-se essencial a sua adaptação considerando os
fármacos comercializados em Portugal. Em 2022 foi desenvolvida a adaptação para a
língua portuguesa da versão 2 destes critérios. Para desenvolver a operacionalização
proposta da versão 3 dos Critérios STOPP/START, procedeu-se à sua tradução e
adaptação para a língua portuguesa e verificou-se para todas as substâncias ativas
incluídas se possuíam Autorização de Introdução no Mercado (AIM) em Portugal. Na
operacionalização proposta os antiarrítmicos de classe IA e 29 outros fármacos foram
excluídos por não possuírem AIM em Portugal. Adicionalmente, através de uma
comparação entre a versão 2 e a versão 3, foram identificados 76 novos critérios, 7
critérios removidos e 69 critérios que sofreram modificações. Estes resultados mostram
o elevado número de alterações e novos critérios introduzidos na versão 3,
evidenciando uma evolução significativa do conhecimento científico em comparação à
versão anterior. Tal facto reforça a importância de operacionalizar a versão mais
recente dos Critérios STOPP/START de modo a obter uma ferramenta útil para os
profissionais de saúde, atualizada e adaptada à realidade nacional. O segundo capítulo aborda os conhecimentos adquiridos durante o estágio em
Farmácia Hospitalar na Unidade Local de Saúde da Cova da Beira. Este capítulo
descreve as áreas de intervenção do farmacêutico hospitalar e as atividades
desenvolvidas nos serviços farmacêuticos durante o estágio que decorreu no período de
5 de fevereiro a 29 de março de 2024.
O terceiro capítulo diz respeito à experiência de estágio em Farmácia Comunitária que
se realizou na Farmácia Nicolau, em Torres Novas, entre 1 de abril e 21 de junho de
2024. Neste capítulo são descritas as competências adquiridas e atividades realizadas
no decorrer do estágio.
The present report was prepared within the scope of the Curricular Unit “Internship” and represents the conclusion of the Integrated Master's Degree in Pharmaceutical Sciences. It is divided into three chapters. The first chapter concerns the research work carried out whose objective was to operationalize the current version of the STOPP/START Criteria for Portugal. The geriatric population is more vulnerable to Drug-Related Problems due to pharmacokinetic and pharmacodynamic changes, higher incidence of chronic diseases and polypharmacy. The growing awareness about the consequences of inappropriate medication prescribing in the elderly has driven the creation of medication review tools to assist healthcare professionals in managing and monitoring medications in elderly patients. The STOPP/START Criteria is a tool developed in a European context that indicates Potentially Inappropriate Medications and possible prescription omissions relevant to this age group. In 2023, the third and most recent version of these criteria was published. Portugal’s population is one of the oldest in the European Union, which is why the application of this tool to optimize prescriptions in the geriatric context should be encouraged. To this end, its adaptation is essential considering the drugs marketed in Portugal. In 2022, was developed the adaptation of version 2 of these criteria to Portuguese. To develop the proposed operationalization of version 3 of the STOPP/START Criteria, it was translated and adapted into Portuguese and it was verified for all the active substances included whether they had Marketing Authorization (MA) in Portugal. In the proposed operationalization, class IA antiarrhythmics and 29 other drugs were excluded because they did not have a MA in Portugal. Additionally, through a comparison between version 2 and version 3, 76 new criteria were identified, 7 removed criteria and 69 criteria that underwent modifications. These results show the high number of changes and new criteria introduced in version 3, highlighting a significant evolution of scientific knowledge compared to the previous version. This fact reinforces the importance of operationalizing the most recent version of the STOPP/START Criteria in order to obtain a useful tool for health professionals, updated and adapted to the national reality. The second chapter addresses the knowledge acquired during the internship in Hospital Pharmacy at the Unidade Local de Saúde da Cova da Beira. This chapter describes the areas of intervention of the hospital pharmacist and the activities carried out in the pharmaceutical services during the internship that took place from February 5th to March 29th, 2024. The third chapter concerns the internship experience in Community Pharmacy that was carried out at Farmácia Nicolau, in Torres Novas, between April 1st and June 21st, 2024. This chapter describes the skills acquired and activities carried out during the internship.
The present report was prepared within the scope of the Curricular Unit “Internship” and represents the conclusion of the Integrated Master's Degree in Pharmaceutical Sciences. It is divided into three chapters. The first chapter concerns the research work carried out whose objective was to operationalize the current version of the STOPP/START Criteria for Portugal. The geriatric population is more vulnerable to Drug-Related Problems due to pharmacokinetic and pharmacodynamic changes, higher incidence of chronic diseases and polypharmacy. The growing awareness about the consequences of inappropriate medication prescribing in the elderly has driven the creation of medication review tools to assist healthcare professionals in managing and monitoring medications in elderly patients. The STOPP/START Criteria is a tool developed in a European context that indicates Potentially Inappropriate Medications and possible prescription omissions relevant to this age group. In 2023, the third and most recent version of these criteria was published. Portugal’s population is one of the oldest in the European Union, which is why the application of this tool to optimize prescriptions in the geriatric context should be encouraged. To this end, its adaptation is essential considering the drugs marketed in Portugal. In 2022, was developed the adaptation of version 2 of these criteria to Portuguese. To develop the proposed operationalization of version 3 of the STOPP/START Criteria, it was translated and adapted into Portuguese and it was verified for all the active substances included whether they had Marketing Authorization (MA) in Portugal. In the proposed operationalization, class IA antiarrhythmics and 29 other drugs were excluded because they did not have a MA in Portugal. Additionally, through a comparison between version 2 and version 3, 76 new criteria were identified, 7 removed criteria and 69 criteria that underwent modifications. These results show the high number of changes and new criteria introduced in version 3, highlighting a significant evolution of scientific knowledge compared to the previous version. This fact reinforces the importance of operationalizing the most recent version of the STOPP/START Criteria in order to obtain a useful tool for health professionals, updated and adapted to the national reality. The second chapter addresses the knowledge acquired during the internship in Hospital Pharmacy at the Unidade Local de Saúde da Cova da Beira. This chapter describes the areas of intervention of the hospital pharmacist and the activities carried out in the pharmaceutical services during the internship that took place from February 5th to March 29th, 2024. The third chapter concerns the internship experience in Community Pharmacy that was carried out at Farmácia Nicolau, in Torres Novas, between April 1st and June 21st, 2024. This chapter describes the skills acquired and activities carried out during the internship.
Description
Keywords
Polimedicação Critérios Stopp/Start Farmácia Comunitária Farmácia Hospitalar Idoso Medicamentos Potencialmente Inapropriados