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Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications

2010-10-16Journal article Restricted access
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dc.contributor.authorCoimbra, Patrícia
dc.contributor.authorFerreira, Paula
dc.contributor.authorSousa, Hermínio C. de
dc.contributor.authorBatista, Patrícia Sofia Pinhanços
dc.contributor.authorRodrigues, Miguel
dc.contributor.authorCorreia, Ilídio Joaquim Sobreira
dc.contributor.authorGil, Maria
dc.date.accessioned2018-03-19T10:37:36Z
dc.date.available2018-03-19T10:37:36Z
dc.date.issued2010-10-16
dc.description.abstractIn this work, porous scaffolds obtained from the freeze-drying of pectin/chitosan polyelectrolyte complexes were prepared and characterized by FTIR, SEM and weight loss studies. Additionally, the cytotoxicity of the prepared scaffolds was evaluated in vitro, using human osteoblast cells. The results obtained showed that cells adhered to scaffolds and proliferated. The study also confirmed that the degradation by-products of pectin/chitosan scaffold are noncytotoxic.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCoimbra, P., Ferreira, P., Sousa, H.C., Batista, P., Rodrigues, M.A., Correia, I.J. e Gil, M. H. (2011) “Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications”, International Journal of Biological Macromolecules, Vol. 48 (1), pp. 112-118pt_PT
dc.identifier.doi10.1016/j.ijbiomac.2010.10.006pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/4627
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0141813010003065#!pt_PT
dc.subjectPolymeric scaffoldpt_PT
dc.subjectPolyelectrolyte complexespt_PT
dc.subjectCytotoxicitypt_PT
dc.subjectOsteoblastspt_PT
dc.titlePreparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage118pt_PT
oaire.citation.startPage112pt_PT
oaire.citation.volume48pt_PT
person.familyNameAlmeida Coimbra
person.familyNameCristina Nunes Ferreira Calvinho
person.familyNameCipriano de Sousa
person.familyNameJoaquim Sobreira Correia
person.familyNameGil
person.givenNamePatrícia Manuela
person.givenNamePaula
person.givenNameHermínio José
person.givenNameIlídio
person.givenNameMaria Helena
person.identifierA-8783-2008
person.identifierUMbJ1KMAAAAJ
person.identifier.ciencia-id111E-0CE2-0C3E
person.identifier.ciencia-idA119-FFB8-0899
person.identifier.ciencia-idF61E-906D-549E
person.identifier.ciencia-idF610-7373-DC81
person.identifier.ciencia-id0E10-A6F7-901B
person.identifier.orcid0000-0003-3393-4427
person.identifier.orcid0000-0002-2629-7805
person.identifier.orcid0000-0003-1613-9675
person.identifier.orcid0000-0003-0657-7751
person.identifier.scopus-author-id55321888200
person.identifier.scopus-author-id57201225798
person.identifier.scopus-author-id7003557499
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication95a46930-ac14-449d-8ddd-db23927062b0
relation.isAuthorOfPublicationa7e98e57-6817-4cd2-95c5-42ebadda09c5
relation.isAuthorOfPublicationdd6ca8c6-7b2f-4f7d-b2a0-8bd9bfdcc888
relation.isAuthorOfPublicationf2c3e779-34a2-4309-950a-80687664c6ad
relation.isAuthorOfPublication676a8017-743a-4f22-93be-4915428f318d
relation.isAuthorOfPublication.latestForDiscovery676a8017-743a-4f22-93be-4915428f318d

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