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Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive textiles

dc.contributor.authorGomes, Ana
dc.contributor.authorMano, João F.
dc.contributor.authorQueiroz, João
dc.contributor.authorGouveia, Isabel C.
dc.date.accessioned2022-01-17T09:41:39Z
dc.date.available2022-01-17T09:41:39Z
dc.date.issued2013
dc.description.abstractIn recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health-care field.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1002/pat.3176pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/11836
dc.language.isoengpt_PT
dc.relationSkin2Tex Old peptides with new faces: A new strategy to develop non-toxic antimicrobial textiles for healthcare applications.
dc.subjectChitosanpt_PT
dc.subjectTextilespt_PT
dc.subjectAlginatept_PT
dc.subjectCottonpt_PT
dc.titleLayer-by-layer deposition of antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive textilespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleSkin2Tex Old peptides with new faces: A new strategy to develop non-toxic antimicrobial textiles for healthcare applications.
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FEBB-BIO%2F113671%2F2009/PT
oaire.citation.endPage1010pt_PT
oaire.citation.issue11pt_PT
oaire.citation.startPage1005pt_PT
oaire.citation.titlePolymers for Advanced Technologiespt_PT
oaire.citation.volume24pt_PT
oaire.fundingStream5876-PPCDTI
person.familyNameGomes
person.familyNameMano
person.familyNameQueiroz
person.familyNameGouveia
person.givenNameAna Paula
person.givenNameJoão
person.givenNameJoão
person.givenNameIsabel Cristina
person.identifier626131
person.identifier.ciencia-id221C-606F-5072
person.identifier.ciencia-id931E-B66D-E341
person.identifier.ciencia-id5711-86D0-A54B
person.identifier.orcid0000-0002-3332-834X
person.identifier.orcid0000-0002-2342-3765
person.identifier.orcid0000-0002-3096-8325
person.identifier.orcid0000-0003-3290-9529
person.identifier.ridA-4418-2009
person.identifier.ridL-3104-2014
person.identifier.ridK-1651-2014
person.identifier.scopus-author-id26643558900
person.identifier.scopus-author-id7003705645
person.identifier.scopus-author-id24328741500
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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