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Abstract(s)
Introdução: A Doença de Dupuytren Ă© uma doença fibroproliferativa de causa ainda desconhecida. Inicialmente traduz-se por um espessamento ao nĂvel da fĂĄscia palmar, contudo poderĂĄ conduzir ao surgimento de contractura em flexĂŁo dos dedos, com consequente compromisso funcional da mĂŁo afectada. Estudos apontam para a influĂȘncia de possĂveis factores de risco em doentes geneticamente susceptĂveis, nomeadamente: hĂĄbitos etĂlicos e tabĂĄgicos, condiçÔes mĂ©dicas como diabetes mellitus e epilepsia ou trabalho manual. Segundo alguns autores, a prevalĂȘncia relatada de Doença de Dupuytren nos doentes alcoĂłlicos, estĂĄ estimada em 28%. Em Portugal, nĂŁo existem estudos publicados que revelem a prevalĂȘncia desta doença na população alcoĂłlica.
Objectivos: Determinar a prevalĂȘncia da Doença de Dupuytren nos doentes alcoĂłlicos, comparar com outros estudos nacionais e internacionais e relacionar a gravidade clĂnica desta doença com o alcoolismo.
Material e mĂ©todos: Foram observados 160 indivĂduos seguidos em consulta de alcoologia do Centro de SaĂșde da CovilhĂŁ. Esta observação decorreu em momento previamente agendado pelo mĂ©dico de alcoologia deste Centro de SaĂșde, entre Dezembro de 2013 e Fevereiro de 2014. A esta amostra foi aplicado um questionĂĄrio, fez-se observação das mĂŁos, que foi realizada apenas por um observador, e recolha de dados do processo clĂnico. Este projecto foi submetido Ă ComissĂŁo de Ătica da Faculdade de CiĂȘncias da SaĂșde.
Resultados: Foram entrevistados 160 indivĂduos, 88,1% eram do gĂ©nero masculino e 11,9% eram do gĂ©nero feminino, a mĂ©dia de idades registada foi de 54,71 anos (DP=8,554). A prevalĂȘncia da Doença de Dupuytren nos doentes alcoĂłlicos da CovilhĂŁ foi de 30,6% [IC 95%:23,46-37,74]. Dos 49 indivĂduos com a doença, 93,9% eram do gĂ©nero masculino e apresentavam uma mĂ©dia de idades de 58,96 anos (DP=10,909). Destes, 73,5% apresentavam trabalho manual ao longo da vida e 95,9% referiram complicaçÔes potencialmente relacionadas com o consumo abusivo de ĂĄlcool. A percentagem de doentes com Doença de Dupuytren que apresentavam histĂłria familiar positiva foi de 20,4%. A doença atingiu maioritariamente a mĂŁo direita e os raios mais afectados foram o 4Âș, seguido do 3Âș. A progressĂŁo da doença nesta amostra evidenciou apenas em casos esporĂĄdicos a presença de contractura mais severa.
DiscussĂŁo/ConclusĂŁo: A prevalĂȘncia da Doença de Dupuytren encontrada neste grupo de doentes foi elevada e semelhante Ă referenciada na literatura para amostras de doentes alcoĂłlicos. Verificou-se que os doentes com esta patologia apresentaram maiores consumos diĂĄrios de bebidas alcoĂłlicas e durante mais anos. TambĂ©m se relacionou a presença de Doença de Dupuytren com trabalho manual ao longo da vida, idade e histĂłria familiar positiva. NĂŁo foi possĂvel estabelecer relação estatisticamente significativa entre esta patologia e hĂĄbitos tabĂĄgicos, diabetes mellitus, epilepsia e artrite reumatoide.
Introduction: Dupuytren's disease is a fibroproliferative disease with unknown cause. Initially reflected by a thickening of the palmar fascia, it can lead to the arising of a contracture in flexion of the fingers, with consequent functional impairment of the affected hand. Studies point to the influence of possible risk factors in genetically susceptible patients, including: ethyl and smoking habits, medical conditions such as diabetes mellitus and epilepsy or manual labor. According to some authors, the reported prevalence of Dupuytren's disease in alcoholic patients is estimated at 28%. In Portugal, there are no published studies that reveal the prevalence of this disease in the alcoholic population. Objectives: To determine the prevalence of Dupuytren's disease in alcoholic patients, comparing with other national and international studies and list the clinical severity of the disease with alcoholism. Material and Methods: Our sample consisted of 160 individuals followed in the alcohology consultation in the Health Center of CovilhĂŁ. This observation took place in previously scheduled time by the alcohology physian in this Health Center, between December 2013 and February 2014. To this sample, a questionnaire was applied, hands were seen by one observer and data was collected from the clinical process. This project was submitted to the Ethics Committee of the Faculty of Health Sciences. Results: 160 individuals were interviewed, 88.1% were male and 11.9% were female, mean age recorded was 54.71 years (SD = 8,554). The prevalence of Dupuytrenâs disease in alcoholic patients of CovilhĂŁ was 30.6% [95% IC: 23,46-37, 74]. Of the 49 individuals with the disease, 93.9% were male and had a mean age of 58.96 years (SD = 10,909). Of these, 73.5% had manual work and 95.9% reported potentially related complications of alcohol abuse. The percentage of patients with Dupuytrenâs disease who had a positive family history was 20.4%. The disease mostly hit the right hand and the most affected rays were 4th, followed by the 3rd. Disease progression in this sample showed only in sporadic cases the presence of more severe contracture. Conclusions: The prevalence of Dupuytrenâs disease found in this group of patients was high and similar to those referenced in the literature for samples of alcoholic patients. It has been found that patients with this disease had higher daily intake of alcoholic beverages and for more years. Also related to the presence of Dupuytrenâs disease was manual labor, age and family history. It wasnât possible to establish statistically significant relationship between this disease and smoking habits, diabetes mellitus, epilepsy and rheumatoid arthritis.
Introduction: Dupuytren's disease is a fibroproliferative disease with unknown cause. Initially reflected by a thickening of the palmar fascia, it can lead to the arising of a contracture in flexion of the fingers, with consequent functional impairment of the affected hand. Studies point to the influence of possible risk factors in genetically susceptible patients, including: ethyl and smoking habits, medical conditions such as diabetes mellitus and epilepsy or manual labor. According to some authors, the reported prevalence of Dupuytren's disease in alcoholic patients is estimated at 28%. In Portugal, there are no published studies that reveal the prevalence of this disease in the alcoholic population. Objectives: To determine the prevalence of Dupuytren's disease in alcoholic patients, comparing with other national and international studies and list the clinical severity of the disease with alcoholism. Material and Methods: Our sample consisted of 160 individuals followed in the alcohology consultation in the Health Center of CovilhĂŁ. This observation took place in previously scheduled time by the alcohology physian in this Health Center, between December 2013 and February 2014. To this sample, a questionnaire was applied, hands were seen by one observer and data was collected from the clinical process. This project was submitted to the Ethics Committee of the Faculty of Health Sciences. Results: 160 individuals were interviewed, 88.1% were male and 11.9% were female, mean age recorded was 54.71 years (SD = 8,554). The prevalence of Dupuytrenâs disease in alcoholic patients of CovilhĂŁ was 30.6% [95% IC: 23,46-37, 74]. Of the 49 individuals with the disease, 93.9% were male and had a mean age of 58.96 years (SD = 10,909). Of these, 73.5% had manual work and 95.9% reported potentially related complications of alcohol abuse. The percentage of patients with Dupuytrenâs disease who had a positive family history was 20.4%. The disease mostly hit the right hand and the most affected rays were 4th, followed by the 3rd. Disease progression in this sample showed only in sporadic cases the presence of more severe contracture. Conclusions: The prevalence of Dupuytrenâs disease found in this group of patients was high and similar to those referenced in the literature for samples of alcoholic patients. It has been found that patients with this disease had higher daily intake of alcoholic beverages and for more years. Also related to the presence of Dupuytrenâs disease was manual labor, age and family history. It wasnât possible to establish statistically significant relationship between this disease and smoking habits, diabetes mellitus, epilepsy and rheumatoid arthritis.
Description
Keywords
Alcoolismo Causalidade Contractura de Dupuytren Epidemiologia PrevalĂȘncia