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Avaliação funcional e conformidade de formulações dermocosméticas para a psoríase, disponíveis no mercado português
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O presente documento foi elaborado no âmbito da Unidade Curricular “Estágio” do
Mestrado Integrado em Ciências Farmacêuticas, e encontra-se estruturado em dois
capítulos principais. O Capítulo I corresponde à componente de investigação, dedicada
ao estudo e análise de formulações dermocosméticas indicadas para psoríase. O Capítulo
II descreve a componente profissionalizante, centrada na experiência em Farmácia
Comunitária.
O capítulo I intitulado “Avaliação funcional e conformidade de formulações
dermocosméticas para psoríase disponíveis no mercado português” é referente à
componentes de investigação. A psoríase é uma doença inflamatória crónica com
impacto significativo na qualidade de vida, cujo tratamento requer uma abordagem
multifatorial. Os dermocosméticos desempenham um papel essencial como terapêutica
de suporte, promovendo a hidratação, a restauração da barreira cutânea e a melhoria da
adesão ao tratamento. Este trabalho teve como objetivo avaliar a conformidade funcional
e a adequação económica das formulações dermocosméticas com indicação para psoríase
disponíveis no mercado português.
Foram identificados 37 produtos de 13 marcas, agrupados em diferentes formas
farmacêuticas, sendo as mais frequentes o creme, a loção e o champô. A análise da
composição demonstrou uma predominância de emolientes e humectantes, com
variações relevantes entre formas farmacêuticas. Os ingredientes-chave mais
prevalentes foram glicerina, ureia, dimeticone e parafina líquida.
A taxa de conformidade global com as recomendações da literatura foi de 76%, com
maior conformidade observada nos bálsamos (92%) e menor nos champôs (57%). A
análise económica revelou uma média de 0,21 ± 0,09 €/mL/g, com custo mensal
estimado de 620 € para um regime padrão de higiene e hidratação.
Os resultados demonstram uma boa adequação funcional da maioria dos produtos,
embora persistam lacunas na presença de ingredientes recomendados (como ceramidas
e queratolíticos) e elevada variabilidade económica. Estes achados reforçam a
necessidade de recomendações nacionais padronizadas e de estudos clínicos que avaliem
o impacto da conformidade na eficácia real e adesão terapêutica. O Capítulo II contempla a experiência e as competências adquiridas durante o estágio
curricular realizado na Farmácia Molelos, em Tondela, no período compreendido entre
3 de fevereiro e 6 de junho, sob a orientação da Dr.ª Carla Soares. É abordado o papel do
farmacêutico na farmácia comunitária, bem como as atividades desenvolvidas ao longo
do estágio.
The present document was prepared within the scope of the curricular unit “Internship” of the Integrated Master’s Degree in Pharmaceutical Sciences and is structured into two main chapters. Chapter I corresponds to the research component, dedicated to the study and analysis of dermocosmetic formulations indicated for psoriasis, while Chapter II describes the professional component, centred on the experience in Community Pharmacy. Chapter I, entitled “Functional evaluation and conformity of dermocosmetic formulations for psoriasis available on the Portuguese market”, refers to the research component. Psoriasis is a chronic inflammatory disease that has a significant impact on quality of life, necessitating a multifactorial therapeutic approach. Dermocosmetics play an essential role as supportive therapy by promoting hydration, restoring the skin barrier, and improving treatment adherence. This study aimed to assess the functional conformity and economic adequacy of dermocosmetic formulations indicated for psoriasis available on the Portuguese market. A total of 37 products from 13 brands were identified, grouped into different pharmaceutical forms, the most frequent being creams, lotions, and shampoos. The compositional analysis showed a predominance of emollients and humectants, with relevant variations across pharmaceutical forms. The most prevalent key ingredients were glycerine, urea, dimethicone, and liquid paraffin. The overall conformity rate with the literature recommendations was 76%, with balms showing the highest conformity (92%) and shampoos the lowest (57%). The economic analysis revealed a mean price of €0.21 ± 0.09 per mL/g, with an estimated monthly cost of €620 for a standard hygiene and hydration regimen. The results demonstrate good functional adequacy for most products, although some gaps remain regarding the inclusion of recommended ingredients (such as ceramides and keratolytics) and considerable economic variability. These findings reinforce the need for standardised national recommendations and clinical studies assessing the impact of formulation conformity on real-world effectiveness and treatment adherence Chapter II describes the experience and skills acquired during the curricular internship carried out at Farmácia Molelos, in Tondela, between February 3 and June 6, under the supervision of Dr Carla Soares. This chapter addresses the role of the pharmacist in community pharmacy, as well as the activities undertaken and experiences gainedp throughout the internship.
The present document was prepared within the scope of the curricular unit “Internship” of the Integrated Master’s Degree in Pharmaceutical Sciences and is structured into two main chapters. Chapter I corresponds to the research component, dedicated to the study and analysis of dermocosmetic formulations indicated for psoriasis, while Chapter II describes the professional component, centred on the experience in Community Pharmacy. Chapter I, entitled “Functional evaluation and conformity of dermocosmetic formulations for psoriasis available on the Portuguese market”, refers to the research component. Psoriasis is a chronic inflammatory disease that has a significant impact on quality of life, necessitating a multifactorial therapeutic approach. Dermocosmetics play an essential role as supportive therapy by promoting hydration, restoring the skin barrier, and improving treatment adherence. This study aimed to assess the functional conformity and economic adequacy of dermocosmetic formulations indicated for psoriasis available on the Portuguese market. A total of 37 products from 13 brands were identified, grouped into different pharmaceutical forms, the most frequent being creams, lotions, and shampoos. The compositional analysis showed a predominance of emollients and humectants, with relevant variations across pharmaceutical forms. The most prevalent key ingredients were glycerine, urea, dimethicone, and liquid paraffin. The overall conformity rate with the literature recommendations was 76%, with balms showing the highest conformity (92%) and shampoos the lowest (57%). The economic analysis revealed a mean price of €0.21 ± 0.09 per mL/g, with an estimated monthly cost of €620 for a standard hygiene and hydration regimen. The results demonstrate good functional adequacy for most products, although some gaps remain regarding the inclusion of recommended ingredients (such as ceramides and keratolytics) and considerable economic variability. These findings reinforce the need for standardised national recommendations and clinical studies assessing the impact of formulation conformity on real-world effectiveness and treatment adherence Chapter II describes the experience and skills acquired during the curricular internship carried out at Farmácia Molelos, in Tondela, between February 3 and June 6, under the supervision of Dr Carla Soares. This chapter addresses the role of the pharmacist in community pharmacy, as well as the activities undertaken and experiences gainedp throughout the internship.
Descrição
Palavras-chave
Dermocosmética Emolientes Farmácia
Comunitária Humectantes Psoríase Queratolíticos