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Anti-microbial coating innovations to prevent infectious diseases (AMiCI): Cost action ca15114

2017-05Journal article Open access
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dc.contributor.authorDunne, Colum
dc.contributor.authorKeinanen-Toivola, Minna
dc.contributor.authorKahru, Anne
dc.contributor.authorTeunissen, Birgit
dc.contributor.authorÖlmez, Hülya
dc.contributor.authorGouveia, Isabel C.
dc.contributor.authorMelo, Luis F.
dc.contributor.authorMurzyn, Kazimierz
dc.contributor.authorModic, Martina
dc.contributor.authorAhonen, Merja
dc.contributor.authorAskew, Pete
dc.contributor.authorPapadopoulos, Theofilos
dc.contributor.authorAdlhart, Christian
dc.contributor.authorCrijns, Francy
dc.date.accessioned2019-11-04T11:48:10Z
dc.date.available2019-11-04T11:48:10Z
dc.date.issued2017-05
dc.description.abstractWorldwide, millions of patients are affected annually by healthcare-associated infection (HCAI), impacting up to 80,000 patients in European Hospitals on any given day. This represents not only public health risk, but also an economic burden. Complementing routine hand hygiene practices, cleaning and disinfection, antimicrobial coatings hold promise based, in essence, on the application of materials and chemicals with persistent bactericidal or -static properties onto surfaces or in textiles used in healthcare environments. The focus of considerable commercial investment and academic research energies, such antimicrobial coating-based approaches are widely believed to have potential in reduction of microbial numbers on surfaces in clinical settings. This belief exists despite definitive evidence as to their efficacy and is based somewhat on positive studies involving, for example, copper, silver or gold ions, titanium or organosilane, albeit under laboratory conditions. The literature describes successful delay and/or prevention of recontamination following conventional cleaning and disinfection by problematic microbes such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococci (VRE), among others. However, there is a scarcity of studies assessing antimicrobial surfaces other than copper in the clinical environment, and a complete lack of published data regarding the successful implementation of these materials on clinically significant outcomes (including HCAI). Through its Cooperation in Science and Technology program (COST), the European Commission has funded a 4-year initiative to establish a network of stakeholders involved in development, regulation and use of novel anti-microbial coatings for prevention of HCAI. The network (AMiCI) comprises participants of more than 60 universities, research institutes and companies across 29 European countries and, to-date, represents the most comprehensive consortium targeting use of these emergent technologies in healthcare settings. More specifically, the network will prioritise coordinated research on the effects (both positive and negative) of antimicrobial coatings in healthcare sectors; know-how regarding availability and mechanisms of action of (nano)-coatings; possible adverse effects of such materials (e.g., potential emergence of microbial resistance or emission of toxic agents into the environment); standardised performance assessments for antimicrobial coatings; identification and dissemination of best practices by hospitals, other clinical facilities, regulators and manufacturers.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1080/21655979.2017.1323593pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/7492
dc.language.isoengpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAcquiredpt_PT
dc.subjectAntimicrobialpt_PT
dc.subjectAntibacterialpt_PT
dc.subjectCoatingspt_PT
dc.subjectCostpt_PT
dc.subjectHealthcarept_PT
dc.subjectHospitalpt_PT
dc.subjectInfectionpt_PT
dc.subjectPreventionpt_PT
dc.subjectRisk-benefit analysispt_PT
dc.titleAnti-microbial coating innovations to prevent infectious diseases (AMiCI): Cost action ca15114pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage685pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage679pt_PT
oaire.citation.titleBioengineeredpt_PT
oaire.citation.volume8pt_PT
person.familyNameDunne
person.familyNameKeinanen-Toivola
person.familyNameKahru
person.familyNameölmez
person.familyNameGouveia
person.familyNameMelo
person.familyNameModic
person.familyNameAhonen
person.familyNamePapadopoulos
person.familyNameAdlhart
person.familyNameCrijns
person.givenNameColum
person.givenNameMinna
person.givenNameAnne
person.givenNamehülya
person.givenNameIsabel Cristina
person.givenNameLuis
person.givenNameMartina
person.givenNameMerja
person.givenNameTheofilos
person.givenNameChristian
person.givenNameFrancy
person.identifier626131
person.identifier1534588
person.identifier.ciencia-id5711-86D0-A54B
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person.identifier.orcid0000-0002-2149-421X
person.identifier.orcid0000-0003-3290-9529
person.identifier.orcid0000-0002-8469-4462
person.identifier.orcid0000-0001-9221-8602
person.identifier.orcid0000-0002-5808-0918
person.identifier.orcid0000-0002-0684-2407
person.identifier.orcid0000-0002-4081-221X
person.identifier.orcid0000-0001-8273-4531
person.identifier.ridC-4927-2008
person.identifier.ridK-1651-2014
person.identifier.ridF-8119-2011
person.identifier.scopus-author-id55259905700
person.identifier.scopus-author-id6603910568
person.identifier.scopus-author-id24328741500
person.identifier.scopus-author-id35508399600
person.identifier.scopus-author-id37109948600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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