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Abstract(s)
A diabetes mellitus (DM) é uma doença crónica que requer cuidados médicos continuados e uma autogestão adequada por parte do individuo, de modo a prevenir e reduzir o risco de complicações a longo termo e sendo a retinopatia diabética (RD) a manifestação ocular mais grave desta doença e uma das principais causas de cegueira do mundo Ocidental, veio o interesse de ser realizado um estudo comparativo com a tomografia de coerência óptica (OCT) em indivíduos com diagnóstico de DM.
O objetivo deste trabalho consistiu em avaliar as alterações estruturais e funcionais na retina causadas pela DM.
A amostra foi constituída por 54 indivíduos com diagnóstico de DM, de ambos os géneros e com idade média de 62,94 ± 7,79 anos. Destes 54, 28 apresentavam um diagnóstico de DM inferior a 10 anos e os restantes 26 com um diagnóstico superior a 10 anos. Para comparação e análise dos resultados, participou no estudo um grupo de controlo de 45 indivíduos sem DM, de ambos os géneros e com idade média de 57,47 ± 5,94 anos. A recolha dos dados foi feita durante os rastreios da RD da região centro no UBIMedical e no Centro Clínico e Experimental em Ciências da Visão.
A análise dos resultados obtidos permitiu concluir que não foram encontradas diferenças estatisticamente significativas na espessura retiniana macular, na espessura da camada das fibras nervosas (RNFL) peripapilar e na sensibilidade ao contraste (SC) entre os indivíduos saudáveis e os indivíduos diabéticos. No entanto, em relação à espessura retiniana macular e à espessura do RNFL peripapilar foram encontradas diferenças entre os géneros e segundo a idade dos indivíduos, sendo que na espessura do RNFL peripapilar houve uma correlação positiva fraca com os valores da HbA1c. Para a SC a idade foi igualmente um fator influenciável. Após a correlação entre a espessuras retiniana e a SC, apenas foi evidente uma correlação positiva fraca entre a espessura retiniana macular e a SC nos indivíduos com diagnóstico de DM.
Diabetes mellitus (DM) is a chronic disease that requires continuous medical care and proper self-administration by the subject, to prevent and reduce the risk of complications in the long term and being diabetic retinopathy (DR) the more severe ocular manifestation of this disease and a leading cause of blindness in the Western world, came the interest to be carried out a comparative study with optical coherence tomography (OCT) in individuals diagnosed with DM. The purpose of this study was to evaluate the structural and functional changes in the retina caused by DM. The sample consisted of 54 individuals diagnosed with DM, of both genders and mean age of 62.94 ± 7.79 years. Of these 54, 28 had a DM diagnosis less than 10 years and the remaining 26 with a superior diagnosis of 10 years. For comparison and analysis of results, participated in the study a control group of 45 subjects without DM, of both genders and mean age of 57.47 ± 5.94 years. The data collection was done during the screening of RD at UBIMedical anda t the Clinical and Experimental Center in Vision Sciences. The analysis of the results concluded that were found statistically significant differences in the macular retinal thickness, the thickness of the layer of nerve fibers (RNFL) peripapillary and contrast sensitivity (CS) between healthy individuals and diabetic subjects. However, with regard to macular retinal thickness and the thickness of the RNFL peripapillary differences were found among the gender and according to the age of the subjects, wherein the thickness of the RNFL peripapillary there was a weak positive correlation with HbA1c. For the SC the age was also one influenced factor. After the correlation between retinal thickness and the SC, only a weak positive correlation was evident between the macular retinal thickness and SC in individuals diagnosed with DM.
Diabetes mellitus (DM) is a chronic disease that requires continuous medical care and proper self-administration by the subject, to prevent and reduce the risk of complications in the long term and being diabetic retinopathy (DR) the more severe ocular manifestation of this disease and a leading cause of blindness in the Western world, came the interest to be carried out a comparative study with optical coherence tomography (OCT) in individuals diagnosed with DM. The purpose of this study was to evaluate the structural and functional changes in the retina caused by DM. The sample consisted of 54 individuals diagnosed with DM, of both genders and mean age of 62.94 ± 7.79 years. Of these 54, 28 had a DM diagnosis less than 10 years and the remaining 26 with a superior diagnosis of 10 years. For comparison and analysis of results, participated in the study a control group of 45 subjects without DM, of both genders and mean age of 57.47 ± 5.94 years. The data collection was done during the screening of RD at UBIMedical anda t the Clinical and Experimental Center in Vision Sciences. The analysis of the results concluded that were found statistically significant differences in the macular retinal thickness, the thickness of the layer of nerve fibers (RNFL) peripapillary and contrast sensitivity (CS) between healthy individuals and diabetic subjects. However, with regard to macular retinal thickness and the thickness of the RNFL peripapillary differences were found among the gender and according to the age of the subjects, wherein the thickness of the RNFL peripapillary there was a weak positive correlation with HbA1c. For the SC the age was also one influenced factor. After the correlation between retinal thickness and the SC, only a weak positive correlation was evident between the macular retinal thickness and SC in individuals diagnosed with DM.
Description
Keywords
Diabetes Mellitus Retinopatia Diabética Sensibilidade Ao Contraste. Tomografia de Coerência Ótica